ChemicalBook > CAS DataBase List > 8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid

8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid

Product Name
8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid
CAS No.
1026201-45-5
Chemical Name
8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid
Synonyms
8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid;8-BroMoH-iMidazo[1,2-a]pyridine-2-carboxylic acid;Imidazo[1,2-a]pyridine-2-carboxylic acid, 8-bromo-;8-Bromo-1,8a-dihydro-imidazo[1,2-a]pyridine-2-carboxylic acid
CBNumber
CB42534181
Molecular Formula
C8H5BrN2O2
Formula Weight
241
MOL File
1026201-45-5.mol
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8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid Property

storage temp. 
2-8°C
Appearance
White to yellow Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B702588
Product name
8-Bromoimidazo[1,2-a]pyridine-2-carboxylicAcid
Packaging
100mg
Price
$65
Updated
2021/12/16
TRC
Product number
B702588
Product name
8-Bromoimidazo[1,2-a]pyridine-2-carboxylicAcid
Packaging
500mg
Price
$220
Updated
2021/12/16
ChemScene
Product number
CS-W000732
Product name
8-Bromoimidazo[1,2-a]pyridine-2-carboxylicacid
Purity
>97.0%
Packaging
250mg
Price
$28
Updated
2021/12/16
ChemScene
Product number
CS-W000732
Product name
8-Bromoimidazo[1,2-a]pyridine-2-carboxylicacid
Purity
>97.0%
Packaging
1g
Price
$74
Updated
2021/12/16
ChemScene
Product number
CS-W000732
Product name
8-Bromoimidazo[1,2-a]pyridine-2-carboxylicacid
Purity
>97.0%
Packaging
5g
Price
$259
Updated
2021/12/16
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8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid Chemical Properties,Usage,Production

Synthesis

1038393-19-9

1026201-45-5

General procedure for the synthesis of 8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid from ethyl 8-bromoimidazo[1,2-a]pyridine-2-carboxylate: Intermediate 37 (2.02 g, 7.4 mmol) was dissolved in a solvent mixture of dioxane and water (16 mL dioxane/4 mL water) and the mixture was cooled in an ice bath. Subsequently, lithium hydroxide (LiOH, 355 mg, 14.8 mmol) was added and the resulting mixture was stirred and reacted at room temperature for 20 hours. After completion of the reaction, the volatile solvent was removed by distillation under reduced pressure. The mixture was cooled again in an ice bath and slowly acidified with aqueous 1 N hydrochloric acid (HCl) to pH 4. The precipitated solid was collected by filtration, washed with cold water (10 mL), and finally dried under vacuum to give Intermediate 39 (1.5 g, 88% yield).

References

[1] Patent: WO2010/70008, 2010, A1. Location in patent: Page/Page column 58
[2] Patent: WO2008/57209, 2008, A1. Location in patent: Page/Page column 51-52

8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid manufacturers

Career Henan Chemical Co
Product
8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid 1026201-45-5
Price
US $7.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
JD724
Release date
2019-09-02

1026201-45-5, 8-bromoimidazo[1,2-a]pyridine-2-carboxylic acidRelated Search:

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  • 8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid
  • Imidazo[1,2-a]pyridine-2-carboxylic acid, 8-bromo-
  • 8-BroMoH-iMidazo[1,2-a]pyridine-2-carboxylic acid
  • 8-Bromo-1,8a-dihydro-imidazo[1,2-a]pyridine-2-carboxylic acid
  • 1026201-45-5