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KD 5170

Product Name
KD 5170
CAS No.
940943-37-3
Chemical Name
KD 5170
Synonyms
KD 5170;KD5170; KD-5170;S-(2-(6-(4-(3-(DiMethylaMino)propoxy)phenylsulfonaMido)pyridin-3-yl)-2-oxoethyl) ethanethioate;S-(2-{6-[({4-[3-(dimethylamino)propoxy]phenyl}sulfonyl)amino]-3-p Yridinyl}-2-oxoethyl) Ethanethioate;Ethanethioic acid, S-[2-[6-[[[4-[3-(dimethylamino)propoxy]phenyl]sulfonyl]amino]-3-pyridinyl]-2-oxoethyl] ester
CBNumber
CB42538280
Molecular Formula
C20H25N3O5S2
Formula Weight
451.56
MOL File
940943-37-3.mol
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KD 5170 Property

Boiling point:
637.9±65.0 °C(Predicted)
Density 
1.310±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
≥21.2 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
form 
solid
pka
9.29±0.28(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
13214
Product name
KD 5170
Purity
≥98%
Packaging
1mg
Price
$34
Updated
2024/03/01
Cayman Chemical
Product number
13214
Product name
KD 5170
Purity
≥98%
Packaging
5mg
Price
$128
Updated
2024/03/01
Cayman Chemical
Product number
13214
Product name
KD 5170
Purity
≥98%
Packaging
10mg
Price
$202
Updated
2024/03/01
Cayman Chemical
Product number
13214
Product name
KD 5170
Purity
≥98%
Packaging
25mg
Price
$465
Updated
2024/03/01
Usbiological
Product number
255590
Product name
KD 5170
Packaging
10mg
Price
$466
Updated
2021/12/16
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KD 5170 Chemical Properties,Usage,Production

Description

KD 5170 is a mercaptoketone-based inhibitor of class I and II histone deacetylases (HDACs; IC50s = 20, 2,060, 75, 26, 950, 14, 85, 2,500, 150, and 18 nM for HDAC1-10, respectively). It exhibits broad spectrum antitumor activity in vitro and in vivo. KD 5170 increases the acetylation of histones and activates caspases 3, 8, and 9, leading to apoptosis in primary myeloma cells.

References

[1]. hassig ca, symons kt, guo x, et al. kd5170, a novel mercaptoketone-based histone deacetylase inhibitor that exhibits broad spectrum antitumor activity in vitro and in vivo. mol cancer ther, 2008, 7(5): 1054-1065.
[2]. payne je, bonnefous c, hassig ca, et al. identification of kd5170: a novel mercaptoketone-based histone deacetylase inhibitor. bioorg med chem lett, 2008, 18(23): 6093-6096.
[3]. feng r, ma h, hassig ca, et al. kd5170, a novel mercaptoketone-based histone deacetylase inhibitor, exerts antimyeloma effects by dna damage and mitochondrial signaling. mol cancer ther, 2008, 7(6): 1494-1505.

KD 5170 Preparation Products And Raw materials

Raw materials

Preparation Products

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KD 5170 Suppliers

China 39 India 1 United States 6 USA 1 Global 47
Chengdu HappySyn Pharmaceutical Technology Co., Ltd.
Tel
028-85114309 15881143215
Email
liangli@happysyn.com
Country
China
ProdList
1722
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55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19918
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55
Beijin Yangguang Furui Chemical co.,Ltd.
Tel
010-57495520 13521095525
Email
zhw512@foxmail.com
Country
China
ProdList
490
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
400-400-400-9004166 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52712
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58
Aishilun biotechnology (Shanghai) co., LTD
Tel
021-50676523 18019098996
Email
info@acelybio.com
Country
China
ProdList
3967
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58
Career Henan Chemica Co
Tel
+86-0371-86658258 15093356674;
Fax
0371-86658258
Email
laboratory@coreychem.com
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China
ProdList
30255
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Henan Weituxi Chemical Technology Co., Ltd.
Tel
0371-63284658 18135795563
Fax
QQ:2885349392
Email
2885349392@qq.com
Country
China
ProdList
9993
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58
Absin Bioscience Inc.
Tel
021-38015121 15000105423
Email
chenjw@absin.cn
Country
China
ProdList
24734
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58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
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8141
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58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
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China
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44489
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TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
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China
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24023
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Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
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Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
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China
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8740
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58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
Tel
021-59167510 18117107507
Email
vip@med-life.cn
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China
ProdList
5019
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58
Guangdong Shengke Biochemical Technology Co., Ltd.
Tel
189-25112307 18925113981
Email
3809205144@qq.com
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China
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10002
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58
ATK CHEMICAL COMPANY LIMITED
Tel
+undefined-21-51877795
Fax
+86 21 5161 9052/ 5187 7796
Email
ivan@atkchemical.com
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China
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32686
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Sichuan Biosynce Pharmatech Co., Ltd.
Tel
+8619950309693
Email
diane@biosynce.com
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China
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4874
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58
LEAPCHEM CO., LTD.
Tel
+86-852-30606658
Email
market18@leapchem.com
Country
China
ProdList
43348
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58
Nanjing Doge Biomedical Technology Co., Ltd
Tel
+86-25-58227606 +86-15305155328
Email
sales@dogechemical.com
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China
ProdList
4128
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58
Shanghai Hao Zhun Biological Technology Co., Ltd.
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--
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info@zzsrm.com
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CHINA
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6846
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Beijing Dongge Boye Biotechnology Co., Ltd.
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--
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1861586486@qq.com
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CHINA
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Shanghai Boyi Biotechnology Co., Ltd.
Tel
--
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Email
15800446246@163.com
Country
CHINA
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5417
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Beijing Fubo Biotechnology Co., Ltd.
Tel
--
Fax
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Email
info@f-biology.com
Country
CHINA
ProdList
6039
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58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
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--
Email
shxiyuanbio@163.com
Country
CHINA
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6921
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58
Beijing Dakco is Biotechnology Co., Ltd.
Tel
--
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--
Email
bj_info@dakewe.net
Country
CHINA
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6348
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58
Shanghai Machine Pure Industrial Co., Ltd.
Tel
--
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--
Email
3245176082@qq.com
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CHINA
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6800
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58
Beijing Bolide Biotechnology Co., Ltd.
Tel
--
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1985563437@qq.com
Country
CHINA
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6172
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Shanghai Yijie Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
SHYIJIEBIO@126.COM
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3510
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Beijing Baiao Innovation Technology Co., Ltd.
Tel
--
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6005
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Morning Student Science and Technology (Guangzhou) Co., Ltd.
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--
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chenxue_gz@163.com
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Shanghai Weiwei Biological Technology Co., Ltd.
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--
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Shanghai Minmin Biotechnology Co., Ltd.
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Boao Pike
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Shanghai Wowu Biological Technology Co., Ltd.
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shhebio@126.com
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Absin Bioscience Inc.
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--
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Email
chenjw@absin.cn
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CHINA
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View Lastest Price from KD 5170 manufacturers

Career Henan Chemica Co
Product
KD 5170 940943-37-3
Price
US $1.80/KG
Min. Order
1g
Purity
96%-99%
Supply Ability
1kg/10kg/100kg
Release date
2020-11-11

940943-37-3, KD 5170Related Search:


  • KD 5170
  • S-(2-(6-(4-(3-(DiMethylaMino)propoxy)phenylsulfonaMido)pyridin-3-yl)-2-oxoethyl) ethanethioate
  • KD5170; KD-5170
  • S-(2-{6-[({4-[3-(dimethylamino)propoxy]phenyl}sulfonyl)amino]-3-p Yridinyl}-2-oxoethyl) Ethanethioate
  • Ethanethioic acid, S-[2-[6-[[[4-[3-(dimethylamino)propoxy]phenyl]sulfonyl]amino]-3-pyridinyl]-2-oxoethyl] ester
  • 940943-37-3