quinuclidin-4-ylMethanaMine
- Product Name
- quinuclidin-4-ylMethanaMine
- CAS No.
- 67496-78-0
- Chemical Name
- quinuclidin-4-ylMethanaMine
- Synonyms
- 4-Aminomethylquinuclidine;quinuclidin-4-ylMethanaMine;Quinnclidine-4-ylmethylamine;1-Azabicyclo[2.2.2]octane-4-methanamine;1-AZABICYCLO[2.2.2]OCTAN-4-YLMETHANAMINE;1-(1-Azabicyclo[2.2.2]oct-4-yl)methanamine;(1-Aza-bicyclo[2.2.2]oct-4-yl)-methylamine;C-(1-Aza-bicyclo[2.2.2]oct-4-yl)-MethylaMine;1-Azabicyclo[2.2.2]octane-4-methanamine 4-Aminomethylquinuclidine
- CBNumber
- CB42561361
- Molecular Formula
- C8H16N2
- Formula Weight
- 140.23
- MOL File
- 67496-78-0.mol
quinuclidin-4-ylMethanaMine Property
- Boiling point:
- 186℃
- Density
- 1.04
- Flash point:
- 63℃
- storage temp.
- 2-8°C(protect from light)
- pka
- 10.67±0.10(Predicted)
- Appearance
- Light yellow to yellow Liquid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- Q990138
- Product name
- Quinuclidin-4-ylmethanamine
- Packaging
- 50mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- CM243490
- Product name
- Quinuclidin-4-ylmethanamine
- Purity
- 95%
- Packaging
- 1g
- Price
- $388
- Updated
- 2021/12/16
- Product number
- 67496780
- Product name
- Quinuclidin-4-ylmethanamine
- Packaging
- 1g
- Price
- $406.7
- Updated
- 2021/12/16
- Product number
- CD11074654
- Product name
- Quinuclidin-4-ylmethanamine
- Purity
- 98%
- Packaging
- 1g
- Price
- $411
- Updated
- 2021/12/16
- Product number
- A244320
- Product name
- Quinuclidin-4-ylmethanamine
- Purity
- 98%
- Packaging
- 1g
- Price
- $474
- Updated
- 2021/12/16
quinuclidin-4-ylMethanaMine Chemical Properties,Usage,Production
Synthesis
26458-78-6
67496-78-0
E) Synthesis of quinuclidinium-4-ylmethylamine 4-Cyanoquinuclidine (0.30 g, 2.2 mmol) was dissolved in ether (5 mL) and slowly added to an ether suspension of lithium aluminum hydride (LAH, 0.167 g, 4.41 mmol). The reaction system was cooled at 0 °C and additional ether (15 mL) was added. Subsequently, the reaction mixture was stirred at 23 °C for 3 hours. Upon completion of the reaction, the reaction was quenched with sodium sulfate decahydrate and stirring was continued for 30 minutes. Next, ethyl acetate was added and after 30 minutes, diatomaceous earth was added and the suspension was filtered through diatomaceous earth. The filtrate was concentrated to dryness to give the oily product quinuclidinium-4-ylmethylamine (0.310 g, quantitative yield). The product was used directly in the subsequent reaction without further purification. 1H NMR (400 MHz, CDCl3) δ ppm: 1.31-1.40 (6H, m), 2.43 (2H, s), 2.86-2.94 (6H, m).
References
[1] Patent: WO2008/124757, 2008, A1. Location in patent: Page/Page column 55
[2] Patent: US2013/79319, 2013, A1. Location in patent: Paragraph 0199; 0200
[3] Patent: US5399562, 1995, A
[4] Patent: US6281226, 2001, B1
[5] Patent: US2009/88418, 2009, A1. Location in patent: Page/Page column 20
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View Lastest Price from quinuclidin-4-ylMethanaMine manufacturers
- Product
- 1-(1-Azabicyclo[2.2.2]oct-4-yl)methanamine 67496-78-0
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-17
- Product
- quinuclidin-4-ylMethanaMine 67496-78-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2019-12-31