(5-BROMO-PYRIMIDIN-2-YL)-(2-METHOXY-ETHYL)-AMINE
- Product Name
- (5-BROMO-PYRIMIDIN-2-YL)-(2-METHOXY-ETHYL)-AMINE
- CAS No.
- 886365-79-3
- Chemical Name
- (5-BROMO-PYRIMIDIN-2-YL)-(2-METHOXY-ETHYL)-AMINE
- Synonyms
- 5-Bromo-(2-methoxyethylamino)pyrimidine;5-Bromo-2-(2-methoxyethylamino)pyrimidine;5-BROMO-N-(2-METHOXYETHYL)PYRIMIDIN-2-AMINE;5-bromo-N-(2-methoxyethyl)-2-Pyrimidinamine;2-Pyrimidinamine, 5-bromo-N-(2-methoxyethyl)-;(5-BROMO-PYRIMIDIN-2-YL)-(2-METHOXY-ETHYL)-AMINE;(5-BROMO-PYRIMIDIN-2-YL)-(2-METHOXY-ETHYL)-AMINE ISO 9001:2015 REACH
- CBNumber
- CB4256210
- Molecular Formula
- C7H10BrN3O
- Formula Weight
- 232.08
- MOL File
- 886365-79-3.mol
(5-BROMO-PYRIMIDIN-2-YL)-(2-METHOXY-ETHYL)-AMINE Property
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B696693
- Product name
- 5-Bromo-(2-methoxyethylamino)pyrimidine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 072042
- Product name
- 5-Bromo-2-(2-methoxyethylamino)pyrimidine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $231
- Updated
- 2021/12/16
- Product number
- W9133
- Product name
- 5-Bromo-2-(2-methoxyethylamino)pyrimidine
- Packaging
- 5g
- Price
- $284
- Updated
- 2021/12/16
- Product number
- W9133
- Product name
- 5-Bromo-2-(2-methoxyethylamino)pyrimidine
- Packaging
- 10g
- Price
- $457
- Updated
- 2021/12/16
- Product number
- 072042
- Product name
- 5-Bromo-2-(2-methoxyethylamino)pyrimidine
- Purity
- 95+%
- Packaging
- 5g
- Price
- $700
- Updated
- 2021/12/16
(5-BROMO-PYRIMIDIN-2-YL)-(2-METHOXY-ETHYL)-AMINE Chemical Properties,Usage,Production
Synthesis
32779-36-5
109-85-3
886365-79-3
To a solution of 5-bromo-2-chloropyrimidine (4 g, 20.68 mmol) in acetonitrile (40 mL) was sequentially added 2-methoxyethylamine (5.5 mL, 63 mmol) and potassium carbonate (14 g, 100 mmol). The reaction mixture was heated and stirred at 100 °C for 6 hours. After completion of the reaction, the solvent was removed by concentration under reduced pressure. The residue was diluted with distilled water (30 mL) and subsequently extracted with dichloromethane (50 mL x 3). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with the eluent of petroleum ether/ethyl acetate (v/v=9/1) to afford the colorless oily target compound 5-bromo-N-(2-methoxyethyl)pyrimidin-2-amine (4.43 g, 92.3% yield). m/z MS (ESI, cation): 233.2 [M+H]+.
References
[1] Patent: WO2016/615, 2016, A1. Location in patent: Paragraph 00725
(5-BROMO-PYRIMIDIN-2-YL)-(2-METHOXY-ETHYL)-AMINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (5-BROMO-PYRIMIDIN-2-YL)-(2-METHOXY-ETHYL)-AMINE manufacturers
- Product
- (5-BROMO-PYRIMIDIN-2-YL)-(2-METHOXY-ETHYL)-AMINE 886365-79-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-01