N-METHYL-N,O-BIS(TRIMETHYLSILYL)HYDROXYLAMINE Property

Boiling point:

155.3±23.0 °C(Predicted)

Density 

1.4146 g/cm3

storage temp. 

Refrigerator

solubility 

sol benzene, toluene, CH2Cl2, CHCl3.

form 

clear liquid

pka

5.95±0.70(Predicted)

color 

Colorless to Light yellow to Light orange

Safety

RIDADR 

UN 2920 8/3/PG II

HS Code 

2931.90.9010

HazardClass 

8/3

PackingGroup 

II

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P363Wash contaminated clothing before reuse.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

N-METHYL-N,O-BIS(TRIMETHYLSILYL)HYDROXYLAMINE Chemical Properties,Usage,Production

Physical properties

bp 40–41 °C/10 mmHg; n20 D 1.4146.2

Uses

As bis-trimethylsilylated N-methylhydroxylamine N-Methyl-N,O-bis(trimethylsilyl)- hydroxylamine can convert aldehydes and ketones to N-methyl nitrones with regio- and chemoselectivity; source of methylnitrene by pyrolysis; source of the trimethylsilyl(methyl)aminyl radical by photolysis.

Preparation

It is obtained in 52% yield by reaction of Nmethylhydroxylamine with chlorotrimethylsilane (2.0 equiv) and triethylamine (3.3 equiv) in ether at 25 °C.