2-chloro-4-fluorobenzo[d]oxazole
- Product Name
- 2-chloro-4-fluorobenzo[d]oxazole
- CAS No.
- 1163123-39-4
- Chemical Name
- 2-chloro-4-fluorobenzo[d]oxazole
- Synonyms
- 2-Chloro-4-fluorobenzoxazole;Benzoxazole, 2-chloro-4-fluoro-;2-chloro-4-fluorobenzo[d]oxazole;2-Chloro-4-fluoro-1,3-benzoxazole
- CBNumber
- CB42574668
- Molecular Formula
- C7H3ClFNO
- Formula Weight
- 171.56
- MOL File
- 1163123-39-4.mol
2-chloro-4-fluorobenzo[d]oxazole Property
- Boiling point:
- 206.9±13.0 °C(Predicted)
- Density
- 1.482±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- pka
- -1.89±0.30(Predicted)
- Appearance
- Light yellow to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C989673
- Product name
- 2-Chloro-4-fluorobenzo[d]oxazole
- Packaging
- 5mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- C989673
- Product name
- 2-Chloro-4-fluorobenzo[d]oxazole
- Packaging
- 10mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- 2428CY
- Product name
- 2-Chloro-4-fluorobenzo[d]oxazole
- Packaging
- 5g
- Price
- $863
- Updated
- 2021/12/16
- Product number
- CD11343236
- Product name
- 2-Chloro-4-fluorobenzo[d]oxazole
- Purity
- 95+%
- Packaging
- 1g
- Price
- $160
- Updated
- 2021/12/16
- Product number
- AA000C33
- Product name
- 2-Chloro-4-fluorobenzo[d]oxazole
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $175
- Updated
- 2021/12/16
2-chloro-4-fluorobenzo[d]oxazole Chemical Properties,Usage,Production
Synthesis
1163123-40-7
1163123-39-4
Step 2: Synthesis of 2-chloro-6-fluorobenzo[d]oxazole To a solution of 560 mg (3.31 mmol) of 4-fluorobenzo[d]oxazole-2-thione in 3.6 mL (49.65 mmol) of thionyl chloride, 60.3 μL of N,N-dimethylformamide was added slowly and dropwise at room temperature. The reaction mixture was stirred at room temperature for 2.5 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The crude product was purified by fast column chromatography on silica gel, using a gradient elution of n-heptane and ethyl acetate to afford 434 mg (76.4% yield) of 2-chloro-6-fluorobenzo[d]oxazole as a white solid. Mass spectrum (m/z): 171 ([M+H]+).
References
[1] Patent: US2009/163485, 2009, A1. Location in patent: Page/Page column 13
2-chloro-4-fluorobenzo[d]oxazole Preparation Products And Raw materials
Raw materials
Preparation Products
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