(+)-Cloprostenol isopropyl ester

Product Name: (+)-Cloprostenol isopropyl ester
CAS No.: 157283-66-4
Chemical Name: (+)-Cloprostenol isopropyl ester
Synonyms: CPG 6112-95;ISOPROPYL CLOPROSTENAT;Isopropyl Cloprostenate;Molnupiravir Impurity 40;Cloprostenol isopropy ester;D-cloprostenol isopropyl ester;(+)-Cloprostenol isopropyl ester;Cloprostenol ecognine isopropyl ester;(+)-Cloprostenol isopropyl ester, ethanol solution;(+)-16-m-chlorophenoxy tetranor Prostaglandin F2α isopropyl ester
CBNumber: CB42589772
Molecular Formula: C25H35ClO6
Formula Weight: 466.99
MOL File: 157283-66-4.mol

More

Less

(+)-Cloprostenol isopropyl ester Property

Boiling point:: 600.0±55.0 °C(Predicted)
Density: 1.227±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form: Oil
pka: 13.41±0.20(Predicted)
color: Colourless
InChIKey: OCNSAYQJDKJOLH-AHTXBMBWSA-N
SMILES: C(OC(C)C)(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1/C=C/[C@@H](O)COC1=CC=CC(Cl)=C1

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 10010016
Product name: (+)-Cloprostenol isopropyl ester
Purity: ≥98%
Packaging: 1mg
Price: $72
Updated: 2024/03/01

Cayman Chemical

Product number: 10010016
Product name: (+)-Cloprostenol isopropyl ester
Purity: ≥98%
Packaging: 5mg
Price: $319
Updated: 2024/03/01

Cayman Chemical

Product number: 10010016
Product name: (+)-Cloprostenol isopropyl ester
Purity: ≥98%
Packaging: 10mg
Price: $565
Updated: 2024/03/01

TRC

Product number: I824300
Product name: IsopropylCloprostenate
Packaging: 100mg
Price: $200
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC07866
Product name: Cloprostenol isopropyl ester
Packaging: 5mg
Price: $69
Updated: 2021/12/16

More

Less

(+)-Cloprostenol isopropyl ester Chemical Properties,Usage,Production

Description

(+)-Cloprostenol is a synthetic analog of prostaglandin F_2α (PGF_2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. It is 200 times more potent than PGF_2α in terminating pregnancy when given subcutaneously at a daily dose of 0.125 μg/kg in rats and hamsters, without the side effects associated with PGF_2α. (+)-Cloprostenol was also shown to be a potent inhibitor of rat adipose precursor differentiation in primary cultures with an IC₅₀ value of 3 x 10-12 M. (+)-Cloprostenol isopropyl ester is a more lipid soluble form of cloprostenol.

Uses

(+)-Cloprostenol isopropyl ester is an isopropyl ester derivative of Cloprostenol (C587300); an aryl-oxymethyl analog of prostaglandin F2α.

in vivo

Cloprostenol isopropyl ester (25 μg/kg; i.p.; daily, for 4 weeks; male mice) induces changes in the evolution of the spermatogenesis and spermiogenesis^[1].
Cloprostenol isopropyl ester (1 μg, 30 μL; injected into the eye; for 2, 4 and 6 h) causes pupil constriction in the cat. Cloprostenol isopropyl ester has an efficacious ocular hypotensive in the lasered monkey^[2].

Animal Model:	Male mice (50–80 days)^[1]
Dosage:	25 μg/kg
Administration:	Intraperitoneal injection; daily, for 4 weeks
Result:	Stimulated the androgen synthesis in a time-dependent manner.

IC 50

FP

References

[1] GINETTE SERRERO Nancy M L. Prostaglandin F2αReceptor (FP Receptor) Agonists Are Potent Adipose Differentiation Inhibitors for Primary Culture of Adipocyte Precursors in Defined Medium[J]. Biochemical and biophysical research communications, 1997, 233 1: Pages 200-202. DOI: 10.1006/bbrc.1997.6433

(+)-Cloprostenol isopropyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(+)-Cloprostenol isopropyl ester Suppliers

China 78 India 1 United Kingdom 1 United States 6 USA 1 Global 87

Taizhou Crene Biotechnology Co. Ltd.

Tel: +86-0576-88813233 +86-13396860566
Email: sales@pharm-intermediates.com
Country: China
ProdList: 1991
Advantage: 58

Hubei Changrun Biomedical Technology Co., Ltd.

Tel: 027-63496417 13007129042
Fax: 13476107660
Email: 3294393103@qq.com
Country: China
ProdList: 295
Advantage: 58

Huigen Biotech (Shanghai) Co., Ltd.

Tel: 13761582449; 13761582449
Email: qingqing_claire@126.com
Country: China
ProdList: 189
Advantage: 58

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14912
Advantage: 59

Taizhou Crene Biotechnology Co., Ltd.

Tel: 0576-88813233 88205808
Fax: 0576-88229589
Email: sales@taizhoukerui.com
Country: China
ProdList: 137
Advantage: 57

Taizhou KEDE Chemical Co., Ltd

Tel: 0576-84613060 13093829633
Fax: 0576-84613060
Email: sales@kedechemical.com
Country: China
ProdList: 299
Advantage: 60

Wuhan Senwayer Century Chemical Co.,Ltd

Tel: 027-86652399 13627115097;
Fax: 86-27-59707018
Email: sales@senwayer.com
Country: China
ProdList: 266
Advantage: 55

Shanghai Synchem Pharma Co., ltd

Tel: 21-619849051-1 18521059765
Email: synchempharma@aliyun.com
Country: China
ProdList: 6468
Advantage: 55

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

More

Less

View Lastest Price from (+)-Cloprostenol isopropyl ester manufacturers

Sinoway Industrial co., ltd.

Product: Isopropyl Cloprostenate 157283-66-4
Price: US $0.00/Kg/Bag
Min. Order: 2Kg/Bag
Purity: 99% up, High Density
Supply Ability: 20 tons
Release date: 2021-08-03

Henan Fengda Chemical Co., Ltd

Product: (+)-Cloprostenol isopropyl ester 157283-66-4
Price: US $8.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-29

Career Henan Chemical Co

Product: (+)-Cloprostenol isopropyl ester 157283-66-4
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: 100kg
Release date: 2018-12-22

157283-66-4, (+)-Cloprostenol isopropyl esterRelated Search:

5-Heptenoic acid,7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-, 1-methylethyl ester, (5Z)-

D-cloprostenol isopropyl ester

ISOPROPYL CLOPROSTENAT

Isopropyl Cloprostenate

(+)-Cloprostenol isopropyl ester

CPG 6112-95

5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, 1-methylethyl ester, (5Z)-

(+)-16-m-chlorophenoxy tetranor Prostaglandin F2α isopropyl ester

(+)-Cloprostenol isopropyl ester, ethanol solution

Cloprostenol isopropy ester

Cloprostenol ecognine isopropyl ester

Molnupiravir Impurity 40

Isopropyl (Z)-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoate

157283-66-4

C25H35ClO6