25-hydroxy Cholesterol-d6

Product Name: 25-hydroxy Cholesterol-d6
CAS No.: 88247-69-2
Chemical Name: 25-hydroxy Cholesterol-d6
Synonyms: 25-hydroxy Cholesterol-d6;cholest-5-ene-3,25-diol-d6;cholest-5-ene-3β,25-diol-d6;CHOLEST-5-ENE-3,25-DIOL-D6;25-HYDROXYCHOLESTEROL-D6;(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-7,7,7-trideuterio-6-hydroxy-6-(trideuteriomethyl)heptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
CBNumber: CB42589994
Molecular Formula: C27H40D6O2
Formula Weight: 408.689910668
MOL File: 88247-69-2.mol

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25-hydroxy Cholesterol-d6 Property

Melting point:: >155°C (dec.)
storage temp.: -20°C
solubility: Chloroform (Slightly), DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated
form: Solid
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 11099
Product name: 25-hydroxy Cholesterol-d6
Purity: ≥99% deuterated forms (d1-d6)
Packaging: 500μg
Price: $63
Updated: 2024/03/01

Cayman Chemical

Product number: 11099
Product name: 25-hydroxy Cholesterol-d6
Purity: ≥99% deuterated forms (d1-d6)
Packaging: 1mg
Price: $117
Updated: 2024/03/01

Cayman Chemical

Product number: 11099
Product name: 25-hydroxy Cholesterol-d6
Purity: ≥99% deuterated forms (d1-d6)
Packaging: 5mg
Price: $486
Updated: 2024/03/01

Usbiological

Product number: 160140
Product name: 25-Hydroxy Cholesterol-d6
Packaging: 1mg
Price: $460
Updated: 2021/12/16

TRC

Product number: H918032
Product name: 25-HydroxyCholesterol-d6
Packaging: 10mg
Price: $1190
Updated: 2021/12/16

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25-hydroxy Cholesterol-d6 Chemical Properties,Usage,Production

Uses

25-Hydroxy Cholesterol-d6, is the labeled analogue of 25-Hydroxy Cholesterol (H918030), which is an oxygenated derivative of Cholesterol (C432501); an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It also induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc.

General Description

25-hydroxycholesterol (25HC) is synthesized from cholesterol in the presence of oxygen and enzyme cholesterol 25-hydroxylase and the conversion is dependent on nicotinamide adenine dinucleotide phosphate (NADPH) during toll-like receptor activation. 25HC is catabolized to 7α-hydroxylated sterol. 25-hydroxycholesterol-d6 is the deuterated form of 25-hydroxycholesterol.

Biochem/physiol Actions

25-hydroxycholesterol inhibits cholesterol biosynthesis by downregulating the function of 3-hydroxy-3-methylglutaryl-CoA reductase. It is found to be implicated in atherosclerosis. 25-hydroxycholesterol levels are known to be increased in hypercholesterolemic condition.

25-hydroxy Cholesterol-d6 Preparation Products And Raw materials

Raw materials

Preparation Products

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25-hydroxy Cholesterol-d6 Suppliers

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88247-69-2, 25-hydroxy Cholesterol-d6Related Search:

25-hydroxy Cholesterol-d6

cholest-5-ene-3,25-diol-d6

CHOLEST-5-ENE-3,25-DIOL-D6;25-HYDROXYCHOLESTEROL-D6

(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-7,7,7-trideuterio-6-hydroxy-6-(trideuteriomethyl)heptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

cholest-5-ene-3β,25-diol-d6

88247-69-2

C27H40D6O2