CAY10618

Product Name: CAY10618
CAS No.: 1202580-59-3
Chemical Name: CAY10618
Synonyms: GPP 78;CAY10618;GPP78,GPP-78;CAY10618 Exclusive;N-(2-phenylphenyl)-8-(4-pyridin-3-yltriazol-1-yl)octanamide;1H-1,2,3-Triazole-1-octanaMide, N-[1,1'-biphenyl]-2-yl-4-(3-pyridinyl)-
CBNumber: CB42590444
Molecular Formula: C27H29N5O
Formula Weight: 439.55
MOL File: 1202580-59-3.mol

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CAY10618 Property

Density: 1.15±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 10 mg/ml
pka: 14.80±0.70(Predicted)
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 13670
Product name: GPP 78
Purity: ≥95%
Packaging: 500μg
Price: $20
Updated: 2024/03/01

Cayman Chemical

Product number: 13670
Product name: GPP 78
Purity: ≥95%
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 13670
Product name: GPP 78
Purity: ≥95%
Packaging: 5mg
Price: $146
Updated: 2024/03/01

Cayman Chemical

Product number: 13670
Product name: GPP 78
Purity: ≥95%
Packaging: 10mg
Price: $257
Updated: 2024/03/01

AK Scientific

Product number: 4481DF
Product name: N-(2-Phenylphenyl)-8-[4-(3-pyridinyl)-1-triazolyl]octanamide
Packaging: 5mg
Price: $262
Updated: 2021/12/16

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CAY10618 Chemical Properties,Usage,Production

Description

Nicotinamide phosphoribosyltransferase (Nampt) converts nicotinamide into nicotinamide mononucleotide (NMN), which is subsequently converted to NAD⁺ by NMN adenyltransferase. Cancer cells commonly have an unusually high rate of NAD⁺ turnover, suggesting that inhibition of Nampt might selectively target cancer cells. GPP 78 is a potent inhibitor of Nampt (IC₅₀ = 3 nM). It induces cell death in the neuroblastoma cell line SH-SY5Y with an IC₅₀ value of 3.8 nM through a process that appears to involve autophagy.

Definition

ChEBI: N-(2-phenylphenyl)-8-[4-(3-pyridinyl)-1-triazolyl]octanamide is a member of biphenyls.

CAY10618 Preparation Products And Raw materials

Raw materials

Preparation Products

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CAY10618 Suppliers

China 23 United States 4 Global 27

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 028-81700200 18108052721
Email: 2850505130@qq.com
Country: China
ProdList: 5176
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29774
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11974
Advantage: 58

1202580-59-3, CAY10618Related Search:

CAY10618

1H-1,2,3-Triazole-1-octanaMide, N-[1,1'-biphenyl]-2-yl-4-(3-pyridinyl)-

GPP 78

CAY10618 Exclusive

N-(2-phenylphenyl)-8-(4-pyridin-3-yltriazol-1-yl)octanamide

GPP78,GPP-78

1202580-59-3