Eicosapentaenoyl Ethanolamide
- Product Name
- Eicosapentaenoyl Ethanolamide
- CAS No.
- 109001-03-8
- Chemical Name
- Eicosapentaenoyl Ethanolamide
- Synonyms
- EPEA;Eicosapentaenoyl Ethanolamide;Eicosapentaenoyl Ethanolamide(solution in ethanol);5(Z),8(Z),11(Z),14(Z),17(Z)-Eicosapentaenoyl Ethanolamide;N-(2-hydroxyethyl)-5(Z),8(Z),11(Z),14(Z),17(Z)-eicosapentaenamide;(5Z,8Z,11Z,14Z,17Z)-N-(2-hydroxyethyl)icosa-5,8,11,14,17-pentaenamide;(5Z,8Z,11Z,14Z,17Z)-N-(2-Hydroxyethyl)-5,8,11,14,17-eicosapentaenamide;5,8,11,14,17-Eicosapentaenamide, N-(2-hydroxyethyl)-, (5Z,8Z,11Z,14Z,17Z)-
- CBNumber
- CB42590909
- Molecular Formula
- C22H35NO2
- Formula Weight
- 345.52
- MOL File
- 109001-03-8.mol
Eicosapentaenoyl Ethanolamide Property
- Boiling point:
- 522.5±50.0 °C(Predicted)
- Density
- 0.951±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
- form
- oil
- pka
- 14.48±0.10(Predicted)
- color
- colorless to yellow
- InChIKey
- OVKKNJPJQKTXIT-JLNKQSITSA-N
- SMILES
- CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCO
Safety
- WGK Germany
- 3
- Storage Class
- 10 - Combustible liquids
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- SML0384
- Product name
- Eicosapentaenoyl ethanolamide
- Purity
- 5mg/mL in absolute ethanol, ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $87.6
- Updated
- 2025/07/31
- Product number
- 10964
- Product name
- Eicosapentaenoyl Ethanolamide
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 10964
- Product name
- Eicosapentaenoyl Ethanolamide
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $115
- Updated
- 2024/03/01
- Product number
- 10964
- Product name
- Eicosapentaenoyl Ethanolamide
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $477
- Updated
- 2024/03/01
- Product number
- 10964
- Product name
- Eicosapentaenoyl Ethanolamide
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $834
- Updated
- 2024/03/01
Eicosapentaenoyl Ethanolamide Chemical Properties,Usage,Production
Uses
Eicosapentaenoyl Ethanolamide inhibits dietary-restriction-induced lifespan extension in wild type and TOR pathway mutant nematodes.
Definition
ChEBI: (5Z,8Z,11Z,14Z,17Z)-icosapentaenoylethanolamine is an N-acylethanolamine 20:5 that is the ethanolamide of (5Z,8Z,11Z,14Z17Z)-eicosapentaenoic acid. It has a role as a PPARgamma agonist. It is an endocannabinoid and a N-acylethanolamine 20:5. It is functionally related to an all-cis-5,8,11,14,17-icosapentaenoic acid.
Biological Activity
Eicosapentaenoyl ethanolamide (EPEA) is a lipid mediator th at has been found to suppress lifespan extension resulting from dietary restriction in C. elegans and also to have antiproliferative and anti-inflammatory actions. In C. elegans, it is believed to act as a metabolic signal th at couples nutrient availability with growth and lifespan. EPEA is a member of the N-acylethanolamines (NAEs), lipid-derived signaling molecules th at include the mammalian endocannabinoid arachidonoyl ethanolamide (AEA). In mammals, NAEs are believed to act primarily through cannabinoid receptors, although they can also interact with a variety of other targets, and EPEA has been shown to act as a CB1 and CB2 receptor agonist. However, C. elegans does not possess clear orthologues of the mammalian cannabinoid receptors which suggests th at there are unidentified NAE receptors in nematodes th at are possibly conserved mediators of NAE signaling.
IC 50
CB1; CB2
Eicosapentaenoyl Ethanolamide Preparation Products And Raw materials
Raw materials
Preparation Products
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