isopropyl cyclopropanesulfonate
- Product Name
- isopropyl cyclopropanesulfonate
- CAS No.
- 146475-51-6
- Chemical Name
- isopropyl cyclopropanesulfonate
- Synonyms
- 2-propyl cyclopropanesulfonate;isopropyl cyclopropanesulfonate;1-Methylethyl cyclopropanesulfonate;Cyclopropanesulfonic acid, 1-methylethyl ester
- CBNumber
- CB42596118
- Molecular Formula
- C6H12O3S
- Formula Weight
- 164.22
- MOL File
- 146475-51-6.mol
isopropyl cyclopropanesulfonate Property
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
Safety
- HS Code
- 2904100090
N-Bromosuccinimide Price
- Product number
- I779110
- Product name
- IsopropylCyclopropanesulfonate
- Packaging
- 500mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- 1896AQ
- Product name
- Isopropylcyclopropanesulfonate
- Packaging
- 1g
- Price
- $178.4
- Updated
- 2021/12/16
- Product number
- OR950828
- Product name
- Isopropylcyclopropanesulfonate
- Purity
- 95%
- Packaging
- 1g
- Price
- $261
- Updated
- 2021/12/16
- Product number
- OR950828
- Product name
- Isopropylcyclopropanesulfonate
- Purity
- 95%
- Packaging
- 5g
- Price
- $769
- Updated
- 2021/12/16
- Product number
- CM203687
- Product name
- isopropylcyclopropanesulfonate
- Purity
- 95+%
- Packaging
- 10g
- Price
- $337
- Updated
- 2021/12/16
isopropyl cyclopropanesulfonate Chemical Properties,Usage,Production
Synthesis
139631-62-2
67-63-0
146475-51-6
Isopropanol (11 L) was slowly added to pyridine (1850 g; 1890 mL) at 20 °C with continuous stirring for 1 hour. Subsequently, the reaction system was cooled to -10 °C to 2 °C and cyclopropanesulfonyl chloride (1100 g) was added dropwise. After the dropwise addition, the reaction was kept at this temperature with continued stirring for 70 hours. Consumption of cyclopropanesulfonyl chloride was confirmed to be 85% by NMR analysis. The reaction mixture was further cooled to 0 °C and an aqueous solution (600 mL) of sodium hydroxide (312 g) was added dropwise. Upon completion of the reaction, the mixture was concentrated to dryness at 45 °C. The concentrate was diluted with ethyl acetate (2750 mL) and methyl tert-butyl ether (1375 mL), stirred for 10 minutes and filtered. To the filtrate was added heptane (1375 mL), filtered again and the filtrate was concentrated to dryness to give 1080 g of isopropyl cyclopropyl sulfonate as a red liquid in 84% yield. The structure of the product was confirmed by 1H NMR (CDCl3, 400 MHz): δ 4.86 (m, 1H), 2.83 (m, 1H), 1.33 (d, 6H), 0.98-1.10 (m, 4H).
References
[1] Patent: US2012/316149, 2012, A1. Location in patent: Page/Page column 13; 14
[2] Patent: WO2012/168884, 2012, A1. Location in patent: Page/Page column 33
[3] Patent: WO2010/145197, 2010, A1. Location in patent: Page/Page column 67-68
[4] Patent: EP3312172, 2018, A1. Location in patent: Paragraph 0399; 0400
isopropyl cyclopropanesulfonate Preparation Products And Raw materials
Raw materials
Preparation Products
isopropyl cyclopropanesulfonate Suppliers
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9310
- Advantage
- 66
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 0551-66399836 18955197623
- sales@enlipharma.com
- Country
- China
- ProdList
- 1876
- Advantage
- 55
- Tel
- 025-58362220 0086-15250997978
- Fax
- 025-58362220
- sale@njxizebio.com
- Country
- China
- ProdList
- 4855
- Advantage
- 55
- Tel
- 13770809694
- Fax
- +86 25 56203983
- googlexu_0114@sina.com
- Country
- China
- ProdList
- 990
- Advantage
- 58
- Tel
- 021-50498136 13564881053
- Fax
- 021-50498136
- products@tbbmed.com
- Country
- China
- ProdList
- 184
- Advantage
- 55
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 13356901049
- Fax
- QQ：1025383091
- 3119594100@qq.com
- Country
- China
- ProdList
- 7964
- Advantage
- 55
- Tel
- 025-66061636 18013972705
- Fax
- (3)02557626880
- qqyang@aikonchem.com
- Country
- China
- ProdList
- 15814
- Advantage
- 58
- Tel
- 0371-55055611 18137792234
- Fax
- QQ：3002694073
- 3002694073@qq.com
- Country
- China
- ProdList
- 9987
- Advantage
- 58