(1R,2S)-2-fluorocyclopropanecarboxylic acid

Product Name: (1R,2S)-2-fluorocyclopropanecarboxylic acid
CAS No.: 167073-08-7
Chemical Name: (1R,2S)-2-fluorocyclopropanecarboxylic acid
Synonyms: (1R,2S)-2-fluorocyclopropane-1-carboxylic acid;Sitafloxacin Impurity 26;(1R,2S)-2-fluorocyclopropanecarboxylic acid;(1R,2S)-trans-2-Fluorocyclopropanecarboxylic acid 97%;Cyclopropanecarboxylic acid, 2-fluoro-, (1R-trans)- (9CI)
CBNumber: CB42610540
Molecular Formula: C4H5FO2
Formula Weight: 104.08
MOL File: 167073-08-7.mol

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(1R,2S)-2-fluorocyclopropanecarboxylic acid Property

Boiling point:: 202.3±33.0 °C(Predicted)
Density: 1.35±0.1 g/cm3(Predicted)
pka: 4.00±0.11(Predicted)
InChI: InChI=1S/C4H5FO2/c5-3-1-2(3)4(6)7/h2-3H,1H2,(H,6,7)/t2-,3-/m0/s1
InChIKey: HZQKMZGKYVDMCT-HRFVKAFMSA-N
SMILES: [C@H]1(C(O)=O)C[C@@H]1F

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Safety

HS Code: 2916200090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P243Take precautionary measures against static discharge.

P273Avoid release to the environment.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Apolloscientific

Product number: PC400539
Product name: (1R,2S)-2-Fluorocyclopropanecarboxylicacid
Purity: 97%
Packaging: 100mg
Price: $319
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2221-3-27
Product name: (1R,2S)-trans-2-Fluorocyclopropanecarboxylic acid
Purity: 97%
Packaging: 100mg
Price: $352
Updated: 2021/12/16

ChemScene

Product number: CS-0053630
Product name: (1R,2S)-2-Fluorocyclopropane-1-carboxylicacid
Packaging: 250mg
Price: $398
Updated: 2021/12/16

Activate Scientific

Product number: AS80256-1R2S
Product name: (1R,2S)-2-Fluorocyclopropane-1-carboxylic acid
Purity: 95% ee
Packaging: 250mg
Price: $529
Updated: 2021/12/16

Apolloscientific

Product number: PC400539
Product name: (1R,2S)-2-Fluorocyclopropanecarboxylicacid
Purity: 97%
Packaging: 250mg
Price: $551
Updated: 2021/12/16

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(1R,2S)-2-fluorocyclopropanecarboxylic acid Chemical Properties,Usage,Production

Synthesis

Dissolve benzyl alcohol and allyl bromide in the solvent, add sodium hydride, and perform a condensation reaction to obtain allyl benzyl ether. The obtained allyl benzyl ether, dichlorofluoromethane, and sodium hydroxide solution are raw materials for carbene reaction to obtain 2-chloro-2-fluorocyclopropylmethyl benzyl ether. Subsequently, the obtained 2-chloro-2-fluorocyclopropylmethylbenzyl ether is hydrogenated and reduced to obtain 2-chloro-2-fluorocyclopropanemethanol. Sodium hypochlorite is added as an oxidizing agent to perform an oxidation reaction to obtain 2-chloro-2-fluorocyclopropanecarboxylic acid. Finally, diethylamine is added to perform a hydrogenation reduction reaction to obtain (1R,2S)-2-fluorocyclopropanecarboxylic acid.

(1R,2S)-2-fluorocyclopropanecarboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(1R,2S)-2-fluorocyclopropanecarboxylic acid Suppliers

China 56 United Kingdom 1 United States 3 Global 60

Suzhou Chukai PharmaTech

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View Lastest Price from (1R,2S)-2-fluorocyclopropanecarboxylic acid manufacturers

Career Henan Chemica Co

Product: (1R,2S)-2-fluorocyclopropanecarboxylic acid 167073-08-7
Price: US $17.00/g
Min. Order: 25g
Purity: 95%
Supply Ability: 1KG
Release date: 2020-10-27

Henan Aochuang Chemical Co.,Ltd.

Product: (1R,2S)-2-fluorocyclopropanecarboxylic acid 167073-08-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-26

167073-08-7, (1R,2S)-2-fluorocyclopropanecarboxylic acidRelated Search:

3-Chloro-2,4,5-trifluorobenzoic acid 3-AMINO-2,4,5-TRIFLUOROBENZOIC ACID 3-Quinolinecarboxylic acid, 6,7- difluoro-1-(2-fluorocyclopropyl)-1,4- dihydro-4-oxo-, cis-(+)- (9CI) Sitafloxacin DU 6858 Cyclopropanamine,2-fluoro-,(1S,2R)-,4-methylbenzenesulfonate(9CI) ETHYL 3-(3-CHLORO-2,4,5-TRIFLUOROPHENYL)-3-OXOPROPANOATE Ethyl 2,4,5-trifluorobenzoylacetate Diphenyl phosphate trans-2-Fluoro-cyclopropanecarboxylic acid DU 6856 Carbamic acid, (2-fluorocyclopropyl)-, 1,1-dimethylethyl ester, cis- (9CI) (1R,2R)-2-fluorocyclopropanecarboxylic acid

(1R,2S)-2-fluorocyclopropanecarboxylic acid

Cyclopropanecarboxylic acid, 2-fluoro-, (1R-trans)- (9CI)

(1R,2S)-2-fluorocyclopropane-1-carboxylic acid

(1R,2S)-trans-2-Fluorocyclopropanecarboxylic acid 97%

Sitafloxacin Impurity 26

167073-08-7