5-nitro-2-(trifluoroMethyl)benzoic acid
- Product Name
- 5-nitro-2-(trifluoroMethyl)benzoic acid
- CAS No.
- 847547-06-2
- Chemical Name
- 5-nitro-2-(trifluoroMethyl)benzoic acid
- Synonyms
- 5-nitro-2-(trifluoroMethyl)benzoic acid;Benzoic acid, 5-nitro-2-(trifluoromethyl)-
- CBNumber
- CB42620684
- Molecular Formula
- C8H4F3NO4
- Formula Weight
- 235.12
- MOL File
- 847547-06-2.mol
5-nitro-2-(trifluoroMethyl)benzoic acid Property
- Boiling point:
- 333.8±42.0 °C(Predicted)
- Density
- 1.596±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 2.61±0.22(Predicted)
- Appearance
- White to light yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P322Specific measures (see …on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 119870
- Product name
- 5-Nitro-2-(trifluoromethyl)benzoic acid
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 119870
- Product name
- 5-Nitro-2-(trifluoromethyl)benzoic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $325
- Updated
- 2021/12/16
- Product number
- HCH0367518
- Product name
- 5-NITRO-2-(TRIFLUOROMETHYL)BENZOIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.86
- Updated
- 2021/12/16
- Product number
- 119870
- Product name
- 5-Nitro-2-(trifluoromethyl)benzoic acid
- Purity
- 95+%
- Packaging
- 5g
- Price
- $965
- Updated
- 2021/12/16
- Product number
- Z5179
- Product name
- 5-Nitro-2-(trifluoromethyl)benzoicacid
- Packaging
- 25g
- Price
- $1371
- Updated
- 2021/12/16
5-nitro-2-(trifluoroMethyl)benzoic acid Chemical Properties,Usage,Production
Synthesis
1960-52-7
847547-06-2
Step 1: Synthesis of 5-nitro-2-(trifluoromethyl)benzoic acid 1. 2-Methyl-4-nitro-1-(trifluoromethyl)benzene (1 g, 4.87 mmol) was dissolved in acetonitrile (30 ml). 2. To the above solution, periodate (H5IO6, 5.56 g, 24.37 mmol) and chromium trioxide (CrO3, 0.126 ml, 3.40 mmol) were added sequentially. 3. the reaction mixture was stirred at room temperature for 2 hrs. 4. Chromium trioxide (0.0722 ml, 1.950 mmol) was added additionally and stirring was continued at room temperature overnight. 5. After completion of the reaction, isopropanol (150 ml) was added to the mixture, at which point the suspension turned green. 6. The precipitate was collected by filtration and the filtrate was concentrated to dryness under reduced pressure. 7. The solid residue was ground with ethyl acetate (40 ml) and filtered to give 5-nitro-2-(trifluoromethyl)benzoic acid (1.1 g, 4.68 mmol, 96% yield).
References
[1] Patent: US2014/155391, 2014, A1. Location in patent: Paragraph 0666; 0667
[2] Patent: WO2014/72220, 2014, A1. Location in patent: Page/Page column 49; 50
[3] Patent: US2005/59668, 2005, A1. Location in patent: Page/Page column 17
5-nitro-2-(trifluoroMethyl)benzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
5-nitro-2-(trifluoroMethyl)benzoic acid Suppliers
- Tel
- 13524892556
- Fax
- (86) 21 51969655， QQ： 263541193
- sales-cn@potentpharm.com
- Country
- China
- ProdList
- 1011
- Advantage
- 55
- Tel
- 400-400-164-7117 18317119277
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 40000
- Advantage
- 60
- Tel
- 021-61478794
- Fax
- 021-61478794
- sales@hcshhai.com
- Country
- China
- ProdList
- 9793
- Advantage
- 50
- Tel
- 13912302692 13912302692;
- Fax
- 0519-88064678
- sales@anxuanchem.com
- Country
- China
- ProdList
- 4825
- Advantage
- 58
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 400-711-5280 86-571-81025280
- Fax
- 86-571-85806285
- sales@molcore.com
- Country
- China
- ProdList
- 9967
- Advantage
- 58
- Tel
- 025-66061636 19370895928
- Fax
- (3)02557626880
- qqyang@aikonchem.com
- Country
- China
- ProdList
- 15813
- Advantage
- 58
- Tel
- +86-400-0216110 +86-15958047586
- Fax
- 0086-21-33275002
- sales@allfluoro.com
- Country
- China
- ProdList
- 11385
- Advantage
- 58
- Tel
- +86-0551-65418684 +8618949823763
- Fax
- 0086-551-65418684
- sales@tnjchem.com
- Country
- China
- ProdList
- 25356
- Advantage
- 58
- Tel
- +86-0086-577-64498589 +86-15355981851
- Fax
- 0086-577-56994596
- sales@win-winchemical.com
- Country
- China
- ProdList
- 14304
- Advantage
- 58