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CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1)

Product Name
CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1)
CAS No.
66592-89-0
Chemical Name
CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1)
Synonyms
Kevetrin HCl;KEVETRIN, NSC 525990;Kevetrin (hydrochloride);Thioureidobutyronitrile HCl;Kevetrin hydrochloride, >98%;3-cyanopropyl carbamimidothioate;Kevetrin hydrochloride >=98% (HPLC);Thioureidobutyronitrile hydrochloride;Kevetrin hydrochloride, 10 mM in DMSO;4-Isothioureidobutyronitrile hydrochloride
CBNumber
CB42624925
Molecular Formula
C5H10ClN3S
Formula Weight
179.67
MOL File
66592-89-0.mol
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CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1) Property

Melting point:
125-127 °C
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO:38.0(Max Conc. mg/mL);211.5(Max Conc. mM)
Water:36.0(Max Conc. mg/mL);200.37(Max Conc. mM)
Ethanol:21.0(Max Conc. mg/mL);116.88(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);55.66(Max Conc. mM)
form 
A crystalline solid
color 
White to off-white
Water Solubility 
H2O: 2mg/mL, clear
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2184
Product name
Kevetrin hydrochloride
Purity
≥98% (HPLC)
Packaging
5mg
Price
$102
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2184
Product name
Kevetrin hydrochloride
Purity
≥98% (HPLC)
Packaging
25mg
Price
$329
Updated
2024/03/01
Cayman Chemical
Product number
28288
Product name
Kevetrin (hydrochloride)
Packaging
5mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
28288
Product name
Kevetrin (hydrochloride)
Packaging
10mg
Price
$104
Updated
2024/03/01
Cayman Chemical
Product number
28288
Product name
Kevetrin (hydrochloride)
Packaging
25mg
Price
$225
Updated
2024/03/01
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CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1) Chemical Properties,Usage,Production

Uses

4-Isothioureidobutyronitrile-13C2, 15N3 Hydrochloride acts as a reagent in the synthesis of nitrile derivatives and their pharmaceutical uses and compositions.

Biological Activity

Kevetrin is an activator/stabilizer of wild type p53 tumor suppressor protein in human lung carcinoma and ovarian cancer cells th at induces cell cycle arrest and apoptosis. Additionally Kevetrin down-regulates oncogenic mutant p53 in OVCAR-3 ovarian cancer cells. Kevetrin inhibits tumor growth in xenograft model of ovarian cancer.

CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1) Preparation Products And Raw materials

Raw materials

Preparation Products

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CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1) Suppliers

Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4727
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58
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
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61
Shanghai Witofly Chemical Co.,Ltd
Tel
Email
sales@witofly.com
Country
China
ProdList
2864
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AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2782
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58
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
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China
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Shanghai JiYi Biotechnology Co. Ltd.
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13621943973
Fax
-
Email
sales@shjiyipharmatech.com
Country
China
ProdList
1166
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Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4573
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55
SPIRO PHARMA
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Fax
-
Email
eric_feng1954@126.com
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China
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Pharmacodia (Beijing) Co.,Ltd
Tel
+86-400-851-9921
Fax
+86-10-82826195
Email
sales@pharmacodia.com
Country
China
ProdList
2317
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55
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862,442785678,326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
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58
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View Lastest Price from CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1) manufacturers

Career Henan Chemical Co
Product
CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1) 66592-89-0
Price
US $1.00/KG
Min. Order
1KG
Purity
95%~99%
Supply Ability
per week:100kg
Release date
2019-09-05

66592-89-0, CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1)Related Search:


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  • KEVETRIN, NSC 525990
  • 3-cyanopropyl carbamimidothioate,hydrochloride
  • Thioureidobutyronitrile hydrochloride
  • 3-Cyanopropyl carbamimidothioate hydrochloride (1:1)
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  • TP53 wild-type,preferential cytotoxic activity,4-Isothioureidobutyronitrile,Inhibitor,inhibit,blast cells,MOLM-13,thioureidobutyronitrile,Kevetrin,thioureido butyronitrile,Kevetrin hydrochloride,myeloid leukemia,MDM-2/p53,KASUMI-1,mutant primary
  • Kevetrin hydrochloride, 10 mM in DMSO
  • 66592-89-0