CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1)

Product Name: CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1)
CAS No.: 66592-89-0
Chemical Name: CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1)
Synonyms: Kevetrin HCl;KEVETRIN, NSC 525990;Kevetrin (hydrochloride);Thioureidobutyronitrile HCl;Kevetrin hydrochloride, >98%;3-cyanopropyl carbamimidothioate;Kevetrin hydrochloride >=98% (HPLC);Thioureidobutyronitrile hydrochloride;Kevetrin hydrochloride, 10 mM in DMSO;4-Isothioureidobutyronitrile hydrochloride
CBNumber: CB42624925
Molecular Formula: C5H10ClN3S
Formula Weight: 179.67
MOL File: 66592-89-0.mol

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CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1) Property

Melting point:: 125-127 °C
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: DMSO:38.0(Max Conc. mg/mL);211.5(Max Conc. mM)
Water:36.0(Max Conc. mg/mL);200.37(Max Conc. mM)
Ethanol:21.0(Max Conc. mg/mL);116.88(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);55.66(Max Conc. mM)
form: A crystalline solid
color: White to off-white
Water Solubility: H2O: 2mg/mL, clear

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2184
Product name: Kevetrin hydrochloride
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $102
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML2184
Product name: Kevetrin hydrochloride
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $329
Updated: 2024/03/01

Cayman Chemical

Product number: 28288
Product name: Kevetrin (hydrochloride)
Packaging: 5mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 28288
Product name: Kevetrin (hydrochloride)
Packaging: 10mg
Price: $104
Updated: 2024/03/01

Cayman Chemical

Product number: 28288
Product name: Kevetrin (hydrochloride)
Packaging: 25mg
Price: $225
Updated: 2024/03/01

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CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1) Chemical Properties,Usage,Production

Uses

4-Isothioureidobutyronitrile-13C2, 15N3 Hydrochloride acts as a reagent in the synthesis of nitrile derivatives and their pharmaceutical uses and compositions.

Biological Activity

Kevetrin is an activator/stabilizer of wild type p53 tumor suppressor protein in human lung carcinoma and ovarian cancer cells th at induces cell cycle arrest and apoptosis. Additionally Kevetrin down-regulates oncogenic mutant p53 in OVCAR-3 ovarian cancer cells. Kevetrin inhibits tumor growth in xenograft model of ovarian cancer.

CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1) Preparation Products And Raw materials

Raw materials

Preparation Products

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CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1) Suppliers

China 67 India 2 United States 9 Global 78

AdooQ BioScience, LLC

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MedChemExpress

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View Lastest Price from CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1) manufacturers

Career Henan Chemical Co

Product: CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1) 66592-89-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%~99%
Supply Ability: per week:100kg
Release date: 2019-09-05

66592-89-0, CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1)Related Search:

CarbaMiMidothioic acid, 3-cyanopropyl ester, hydrochloride (1:1)

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TP53 wild-type,preferential cytotoxic activity,4-Isothioureidobutyronitrile,Inhibitor,inhibit,blast cells,MOLM-13,thioureidobutyronitrile,Kevetrin,thioureido butyronitrile,Kevetrin hydrochloride,myeloid leukemia,MDM-2/p53,KASUMI-1,mutant primary

Kevetrin hydrochloride, 10 mM in DMSO

66592-89-0