ChemicalBook > CAS DataBase List > Ketone Ester

Ketone Ester

Product Name
Ketone Ester
CAS No.
1208313-97-6
Chemical Name
Ketone Ester
Synonyms
(R)-3-hydroxybutyl (R)-3-hydroxybutyrate;[(3R)-3-hydroxybutyl] (3R)-3-hydroxybutanoate;R-BHB;BD-AcAc 2;Ketone Ester;Ketone Ester (R-BHB);(R)-(R)-3-hydroxybutyl 3-hydroxybutanoate;Ketone ester D-BHB R-BHB Beta-hydroxybutyrate;(3R)-3-Hydroxybutanoic acid (3R)-3-hydroxybutyl ester;Butanoic acid, 3-hydroxy-, (3R)-3-hydroxybutyl ester, (3R)-
CBNumber
CB42628004
Molecular Formula
C8H16O4
Formula Weight
176.21
MOL File
1208313-97-6.mol
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Ketone Ester Property

Boiling point:
269℃
Density 
1.102
Flash point:
101℃
storage temp. 
Store at -20°C
solubility 
Methyl Acetate: 50 mg/ml
pka
14.38±0.20(Predicted)
form 
Liquid
color 
Colorless to light yellow
InChI
InChI=1S/C8H16O4/c1-6(9)3-4-12-8(11)5-7(2)10/h6-7,9-10H,3-5H2,1-2H3/t6-,7-/m1/s1
InChIKey
AOWPVIWVMWUSBD-RNFRBKRXSA-N
SMILES
C(OCC[C@H](O)C)(=O)C[C@H](O)C
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology
Product number
A3526
Product name
KetoneEster
Packaging
100mg
Price
$629
Updated
2021/12/16
Crysdot
Product number
CD31004279
Product name
KetoneEster
Purity
98+%
Packaging
100mg
Price
$279
Updated
2021/12/16
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Ketone Ester Chemical Properties,Usage,Production

Uses

Ketone ester is exogenous ketone bodies that may promote ketosis in humans. Studies on animals have shown that ketone esters can have positive effects on Alzheimer's disease by decreasing amyloid buildup, reducing neurofibrillary tangles and tau, and enhancing learning and memory.

Preparation

Ketone ester can be prepared by reacting (3R)-3-hydroxybutyl methyl ester with tert-butyl dimethylchlorosilane.

benefits

Ketone esters can help with muscle recovery after exercising. They increase the rate of energy store replenishment in the body and support the process of rebuilding muscles. They also decrease the amount of muscle breakdown. The various forms of ketone esters that have been utilized include R,S-1,3-butanediol diacetoacetate (BD-AcAc2, ketone diester), D-β-hydroxybutyrate-(R)-1,3 butanediol (ketone monoester), and Bis-hexanoyl (R)-1,3-butanediol (BH-BD), among others.?

Biological Activity

Ketone ester–enriched diets that induce sustained ketonemia reduce pathological cardiac remodeling and enhance ventricular function in multiple heart failure models across both mice and rats using both prevention and treatment strategies.

Safety

Taking ketone supplements can cause extreme stomach upset in some people. This side effect can limit the number of supplements that a person can take. Taking ketone salts also increases the risk of electrolyte imbalances. Electrolytes are vital for the conduction of electrical signals in the muscles and neurons.

in vivo

Blood glucose decreased by about 50% from 5 to 2.8 mM while insulin decreased from 0.54 to 0.26 ng/ml in rats fed a diet where 30% of the calories from starch were replaced with ketone esters (20). Plasma leptin was also decreased from 3.12 to 1.83 ng/ml in rats, where ketone esters were substituted equi-calorically for starch. The ability of the metabolism of ketone bodies to increase insulin sensitivity has been demonstrated previously in the working perfused rat heart[1].

References

[1] Veech R, High electron mobility triazine for lower driving voltage and higher efficiency organic light emitting devices. Journal of Lipid Research, 2014; 55: 2004-2006.

Ketone Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ketone Ester manufacturers

airuikechemical co., ltd.
Product
Dioctyl terephthalate 1208313-97-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
20 tons
Release date
2024-03-13
airuikechemical co., ltd.
Product
Ketone Ester 1208313-97-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
20 tons
Release date
2024-04-03
Wuhan Haorong Biotechnology Co.,Ltd
Product
Ketone Ester 1208313-97-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500
Release date
2023-07-20

1208313-97-6, Ketone EsterRelated Search:


  • Ketone Ester
  • (3R)-3-Hydroxybutanoic acid (3R)-3-hydroxybutyl ester
  • BD-AcAc 2
  • [(3R)-3-hydroxybutyl] (3R)-3-hydroxybutanoate
  • R-BHB
  • Butanoic acid, 3-hydroxy-, (3R)-3-hydroxybutyl ester, (3R)-
  • (R)-(R)-3-hydroxybutyl 3-hydroxybutanoate
  • (R)-3-hydroxybutyl (R)-3-hydroxybutyrate
  • Ketone Ester (R-BHB)
  • Ketone,endurance,blood glucose,nutritional ketones,BDAcAc 2,diabetes,muscle weakness,Inhibitor,exercise performance,Parkinson’s disease,BD AcAc 2,inhibit,(R,R)-Ketone Ester
  • Ketone ester D-BHB R-BHB Beta-hydroxybutyrate
  • 1208313-97-6
  • 1208313-97-6