ChemicalBook > CAS DataBase List > Radiprodil

Radiprodil

Product Name: Radiprodil
CAS No.: 496054-87-6
Chemical Name: Radiprodil
Synonyms: RGH 896;Radiprodil;Radiprodil (RGH-896);RGH 896;RGH 896;RGH896;Radiprodil, 10 mM in DMSO;Radiprodil,RGH896,Ionotropic glutamate receptors,RGH 896,iGluR,inhibit,Inhibitor;2-[4-(4-Fluorobenzyl)piperidin-1-yl]-2-oxo-N-(2-oxo-2,3-dihydrobenzoxazol-6-yl)acetamide;2-(4-(4-Fluorobenzyl)piperidin-1-yl)-2-oxo-N-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)acetamide;2-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]-2-oxo-N-(2-oxo-3H-1,3-benzoxazol-6-yl)acetamide;1-Piperidineacetamide, N-(2,3-dihydro-2-oxo-6-benzoxazolyl)-4-[(4-fluorophenyl)methyl]-α-oxo-
CBNumber: CB42628347
Molecular Formula: C21H20FN3O4
Formula Weight: 397.41
MOL File: 496054-87-6.mol

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Radiprodil Property

Melting point:: 223-225 °C
Density: 1.394±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF: 2mg/mL; DMSO: 10mg/mL; DMSO:PBS (pH 7.2) (1:3): 0.25mg/mL
form: A solid
pka: 8.62±0.70(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29712
Product name: Radiprodil
Packaging: 5mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 29712
Product name: Radiprodil
Packaging: 50mg
Price: $801
Updated: 2024/03/01

Cayman Chemical

Product number: 29712
Product name: Radiprodil
Packaging: 10mg
Price: $206
Updated: 2024/03/01

Cayman Chemical

Product number: 29712
Product name: Radiprodil
Packaging: 25mg
Price: $481
Updated: 2024/03/01

TRC

Product number: R071820
Product name: Radiprodil
Packaging: 1mg
Price: $140
Updated: 2021/12/16

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Radiprodil Chemical Properties,Usage,Production

Uses

Radiprodil is used in the preparation of oximides as novel NR2B selective NMDA receptor anatagonists.

in vivo

Radiprodil could block NMDA currents in Mg²⁺ insensitive variants, with potencies similar to those obtained without Mg²⁺^[3].
Radiprodil's potency is higher at pH 7.0 than at pH 7.6, suggesting that radiprodil may retain its ability to block glutamate-induced NMDA currents even under acidic conditions that manifest under long term seizures^[3].

Radiprodil Preparation Products And Raw materials

Raw materials

Preparation Products

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496054-87-6, RadiprodilRelated Search:

Radiprodil

RGH 896

2-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]-2-oxo-N-(2-oxo-3H-1,3-benzoxazol-6-yl)acetamide

RGH 896;RGH 896;RGH896

2-[4-(4-Fluorobenzyl)piperidin-1-yl]-2-oxo-N-(2-oxo-2,3-dihydrobenzoxazol-6-yl)acetamide

1-Piperidineacetamide, N-(2,3-dihydro-2-oxo-6-benzoxazolyl)-4-[(4-fluorophenyl)methyl]-α-oxo-

Radiprodil (RGH-896)

Radiprodil,RGH896,Ionotropic glutamate receptors,RGH 896,iGluR,inhibit,Inhibitor

2-(4-(4-Fluorobenzyl)piperidin-1-yl)-2-oxo-N-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)acetamide

Radiprodil, 10 mM in DMSO

496054-87-6