ChemicalBook > CAS DataBase List > N4-Benzoyl-7'-OH-N-trityl Morpholino cytosine

N4-Benzoyl-7'-OH-N-trityl Morpholino cytosine

Product Name: N4-Benzoyl-7'-OH-N-trityl Morpholino cytosine
CAS No.: 125515-31-3
Chemical Name: N4-Benzoyl-7'-OH-N-trityl Morpholino cytosine
Synonyms: PMO-C Precusor;Morpholino-C(Bz);N4-Benzoyl-7'-OH-N-trityl Morpholino cytosine;N4-Benzoyl-7'-OH-N-trityl Morpholino cytosine;N-benzoyl-7-hydroxy-N-trityl morpholinocytidine;N4-Benzoyl-7'-hydroxymorpholino cytidine monomer;N4-Benzoyl-7'-hydroxy-N-trityl-morpholino cytosine monomer;N-(1-(6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-2-oxo-1, 2-dihydropyrimidin-4-yl)benzamide;N-{1-[(2R,6)-6-(hydroxymethyl)-4tritylmorpholin-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl}benzamide;N-[1-[(2R,6S)-6-(Hydroxymethyl)-4-tritylmorpholin-2-yl]-2-oxo-1,2-dihydropyrimidine-4-yl]benzamide
CBNumber: CB42630869
Molecular Formula: C35H32N4O4
Formula Weight: 572.65
MOL File: 125515-31-3.mol

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N4-Benzoyl-7'-OH-N-trityl Morpholino cytosine Property

Density: 1.24±0.1 g/cm3(Predicted)
pka: 8.65±0.20(Predicted)
InChIKey: DMFVVKPXZHMPKX-XDFJSJKPSA-N
SMILES: C(NC1C=CN([C@@H]2O[C@H](CO)CN(C(C3=CC=CC=C3)(C3=CC=CC=C3)C3=CC=CC=C3)C2)C(=O)N=1)(=O)C1=CC=CC=C1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: NB138534
Product name: N4-Benzoyl-7'-hydroxy-N-trityl-morpholino cytosine monomer
Packaging: 1g
Price: $800
Updated: 2021/12/16

AK Scientific

Product number: 8788CW
Product name: N-[1-(6-Hydroxymethyl-4-trityl-morpholin-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-benzamide
Packaging: 1g
Price: $1130
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NB138534
Product name: N4-Benzoyl-7'-hydroxy-N-trityl-morpholino cytosine monomer
Packaging: 2g
Price: $1300
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NB138534
Product name: N4-Benzoyl-7'-hydroxy-N-trityl-morpholino cytosine monomer
Packaging: 5G
Price: $2500
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NB138534
Product name: N4-Benzoyl-7'-hydroxy-N-trityl-morpholino cytosine monomer
Packaging: 10g
Price: $3950
Updated: 2021/12/16

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N4-Benzoyl-7'-OH-N-trityl Morpholino cytosine Chemical Properties,Usage,Production

Uses

N4-Benzoyl-7’-OH-N-trityl morpholino cytosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

N4-Benzoyl-7'-OH-N-trityl Morpholino cytosine Preparation Products And Raw materials

Raw materials

Preparation Products

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125515-31-3, N4-Benzoyl-7'-OH-N-trityl Morpholino cytosineRelated Search:

N4-Benzoyl-7'-OH-N-trityl Morpholino cytosine

N-[1-[(2R,6S)-6-(Hydroxymethyl)-4-tritylmorpholin-2-yl]-2-oxo-1,2-dihydropyrimidine-4-yl]benzamide

N4-Benzoyl-7'-hydroxymorpholino cytidine monomer

N4-Benzoyl-7'-hydroxy-N-trityl-morpholino cytosine monomer

N-{1-[(2R,6)-6-(hydroxymethyl)-4tritylmorpholin-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl}benzamide

N-(1-(6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-2-oxo-1, 2-dihydropyrimidin-4-yl)benzamide

PMO-C Precusor

Benzamide, N-[1,2-dihydro-1-[(2R,6S)-6-(hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-2-oxo-4-pyrimidinyl]-

Morpholino-C(Bz)

N-benzoyl-7-hydroxy-N-trityl morpholinocytidine

N4-Benzoyl-7'-OH-N-trityl Morpholino cytosine

N-(1-[(2R,6S)-6-(hydroxymethyl)-4-(triphenylmethyl)morpholin-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide

Benzamide, N-[1,2-dihydro-1-[6-(hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-2-oxo-4-pyrimidinyl]-, (2R-cis)- (9CI)

125515-31-3