ChemicalBook > CAS DataBase List > Rimegepant

Rimegepant

Product Name
Rimegepant
CAS No.
1289023-67-1
Chemical Name
Rimegepant
Synonyms
BMS-927711;BMS 927711;CS-2806;BHV-3000;BMS 92771;Rimegepan;Remazepam;Rimegepant;BMS927711;BMS 927711;BMS-927711(Rimegepant)
CBNumber
CB42645135
Molecular Formula
C28H28F2N6O3
Formula Weight
534.56
MOL File
1289023-67-1.mol
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Rimegepant Property

Density 
1.45±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
A crystalline solid
pka
12.03±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26338
Product name
Rimegepant
Packaging
1mg
Price
$43
Updated
2023/06/20
Cayman Chemical
Product number
26338
Product name
Rimegepant
Packaging
5mg
Price
$189
Updated
2023/06/20
Cayman Chemical
Product number
26338
Product name
Rimegepant
Packaging
10mg
Price
$334
Updated
2023/06/20
Cayman Chemical
Product number
26338
Product name
Rimegepant
Packaging
25mg
Price
$678
Updated
2023/06/20
TRC
Product number
R517100
Product name
Rimegepant
Packaging
500mg
Price
$15225
Updated
2021/12/16
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Rimegepant Chemical Properties,Usage,Production

Description

Rimegepant (Nurtec ODT)(FDA approved in February 2020) is an ODT available in a single strength of 75 mg for the acute treatment of migraine with or without aura in adults.No more than 75 mg should be taken in a 24-hour period. while there are no contraindications,concomitant administration with CYP3A4 inhibitors should be avoided.The most common adverse reaction is nausea, occurring in few patients (rimegepant PI, 2020). In clinical trials, a single 75-mg dose of rimegepant demonstrated superiority over placebo with regard to freedom from pain (21% in the rimegepant group vs.11% in the placebo group) and freedom from the most bothersome symptom (35% vs. 27%) at 2 hours post dose (Croop et al., 2019). Rimegepant is not approved for migraine prevention, although it is presently in late-stage clinical trials assessing it for that indication(NCT03732638,2020).

Uses

Rimegepant is an oral calcitonin gene-related peptide (CGRP) receptor antagonist used for the treatment of migraine.

Rimegepant Preparation Products And Raw materials

Raw materials

Preparation Products

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Rimegepant Suppliers

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View Lastest Price from Rimegepant manufacturers

shandong perfect biotechnology co.ltd
Product
BMS-927711 1289023-67-1
Price
US $0.00/g
Min. Order
1g
Purity
98% HPLC
Supply Ability
100kg
Release date
2023-08-14
Hebei Yanxi Chemical Co., Ltd.
Product
Rimegepant 1289023-67-1
Price
US $20.00/KG
Min. Order
1KG
Purity
0.99
Supply Ability
20
Release date
2023-09-05
Henan Bao Enluo International TradeCo.,LTD
Product
Rimegepant 1289023-67-1
Price
US $150.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
10000MT
Release date
2023-05-29

1289023-67-1, RimegepantRelated Search:


  • BMS 927711
  • BMS-927711
  • 4-(2,3-Dihydro-2-oxo-1H-imidazo[4,5-b]pyridin-1-yl)-1-piperidinecarboxylic acid (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl ester
  • Rimegepant
  • CS-2806
  • BMS-927711(Rimegepant)
  • BMS 92771
  • RIMEGEPANT;BMS-927711;BMS927711;BMS 92771
  • (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate
  • 1-Piperidinecarboxylic acid, 4-(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]pyridin-1-yl)-, (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl ester
  • BMS927711;BMS 927711
  • BHV-3000
  • Rimegepant (BMS927711)
  • Rimegepan
  • Remazepam
  • 1289023-67-1
  • C28H28F2N6O3
  • API
  • 1289023-67-1