Rimegepant

ChemicalBook > CAS DataBase List > Rimegepant

Product Name: Rimegepant
CAS No.: 1289023-67-1
Chemical Name: Rimegepant
Synonyms: BMS-927711;BMS 927711;CS-2806;BHV-3000;BMS 92771;Rimegepan;Remazepam;Rimegepant;BMS927711;BMS 927711;BMS-927711(Rimegepant)
CBNumber: CB42645135
Molecular Formula: C28H28F2N6O3
Formula Weight: 534.56
MOL File: 1289023-67-1.mol

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Rimegepant Property

Density: 1.45±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: A crystalline solid
pka: 12.03±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 26338
Product name: Rimegepant
Packaging: 1mg
Price: $43
Updated: 2023/06/20

Cayman Chemical

Product number: 26338
Product name: Rimegepant
Packaging: 5mg
Price: $189
Updated: 2023/06/20

Cayman Chemical

Product number: 26338
Product name: Rimegepant
Packaging: 10mg
Price: $334
Updated: 2023/06/20

Cayman Chemical

Product number: 26338
Product name: Rimegepant
Packaging: 25mg
Price: $678
Updated: 2023/06/20

TRC

Product number: R517100
Product name: Rimegepant
Packaging: 500mg
Price: $15225
Updated: 2021/12/16

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Rimegepant Chemical Properties,Usage,Production

Description

Rimegepant (Nurtec ODT)(FDA approved in February 2020) is an ODT available in a single strength of 75 mg for the acute treatment of migraine with or without aura in adults.No more than 75 mg should be taken in a 24-hour period. while there are no contraindications，concomitant administration with CYP3A4 inhibitors should be avoided.The most common adverse reaction is nausea, occurring in few patients (rimegepant PI, 2020). In clinical trials, a single 75-mg dose of rimegepant demonstrated superiority over placebo with regard to freedom from pain (21% in the rimegepant group vs.11% in the placebo group) and freedom from the most bothersome symptom (35% vs. 27%) at 2 hours post dose (Croop et al., 2019). Rimegepant is not approved for migraine prevention, although it is presently in late-stage clinical trials assessing it for that indication(NCT03732638,2020).

Uses

Rimegepant is an oral calcitonin gene-related peptide (CGRP) receptor antagonist used for the treatment of migraine.

Rimegepant Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Rimegepant manufacturers

shandong perfect biotechnology co.ltd

Product: BMS-927711 1289023-67-1
Price: US $0.00/g
Min. Order: 1g
Purity: 98% HPLC
Supply Ability: 100kg
Release date: 2023-08-14

Cangzhou Kangrui Pharma Tech Co. Ltd.,

Product: Rimegepant 1289023-67-1
Price: US $0.00-0.00/g
Min. Order: 10g
Purity: 99%
Supply Ability: 5kgs
Release date: 2024-11-05

Hebei Yanxi Chemical Co., Ltd.

Product: Rimegepant 1289023-67-1
Price: US $20.00/KG
Min. Order: 1KG
Purity: 0.99
Supply Ability: 20
Release date: 2023-09-05

1289023-67-1, RimegepantRelated Search:

BMS 927711

BMS-927711

4-(2,3-Dihydro-2-oxo-1H-imidazo[4,5-b]pyridin-1-yl)-1-piperidinecarboxylic acid (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl ester

Rimegepant

CS-2806

BMS-927711(Rimegepant)

BMS 92771

RIMEGEPANT;BMS-927711;BMS927711;BMS 92771

(5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate

1-Piperidinecarboxylic acid, 4-(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]pyridin-1-yl)-, (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl ester

BMS927711;BMS 927711

BHV-3000

Rimegepant (BMS927711)

Rimegepan

Remazepam

(5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)- 6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbo

1289023-67-1

C28H28F2N6O3

API

1289023-67-1