H-Glu(OMe)-OtBu
- Product Name
- H-Glu(OMe)-OtBu
- CAS No.
- 79640-72-5
- Chemical Name
- H-Glu(OMe)-OtBu
- Synonyms
- 1-(tert-Butyl) 5-methyl L-glutamate;(S)-1-tert-Butyl 5-methyl 2-aminopentanedioate;1-O-tert-butyl5-O-methyl(2S)-2-aminopentanedioate;L-Glutamic acid, 1-(1,1-dimethylethyl) 5-methyl ester
- CBNumber
- CB42645377
- Molecular Formula
- C10H19NO4
- Formula Weight
- 217.26
- MOL File
- 79640-72-5.mol
H-Glu(OMe)-OtBu Property
- Boiling point:
- 268.8±25.0 °C(Predicted)
- Density
- 1.061±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 6.85±0.35(Predicted)
N-Bromosuccinimide Price
- Product number
- T135840
- Product name
- (S)-1-tert-Butyl5-Methyl2-Aminopentanedioate
- Packaging
- 500mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- T135840
- Product name
- (S)-1-tert-Butyl5-Methyl2-Aminopentanedioate
- Packaging
- 1g
- Price
- $330
- Updated
- 2021/12/16
- Product number
- FB142529
- Product name
- (S)-1-tert-Butyl 5-methyl 2-aminopentanedioate
- Packaging
- 500mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- FB142529
- Product name
- (S)-1-tert-Butyl 5-methyl 2-aminopentanedioate
- Packaging
- 1g
- Price
- $98
- Updated
- 2021/12/16
- Product number
- FB142529
- Product name
- (S)-1-tert-Butyl 5-methyl 2-aminopentanedioate
- Packaging
- 2g
- Price
- $171
- Updated
- 2021/12/16
H-Glu(OMe)-OtBu Chemical Properties,Usage,Production
Synthesis
540-88-5
3077-51-8
79640-72-5
GENERAL METHOD: Under vigorous stirring conditions, 82 mL of tert-butyl acetate was slowly added to 2.45 mL of 58% HClO4 solution containing 12.2 mmol of methyl ester 6 or 7 hydrochloride. The reaction mixture was stirred continuously at room temperature for 72 hours. Upon completion of the reaction, the mixture was slowly poured into a mixture of 270 mL of 10% Na2CO3 solution with 40 mL of Et2O that had been pre-cooled to 5°C. After separation of the organic phase, the aqueous phase was extracted with Et2O (2 x 70 mL) to recover the reaction product. All organic phases were combined and washed sequentially with 10% Na2CO3 solution (2 × 100 mL), dried over anhydrous Na2SO4 and subsequently concentrated under reduced pressure. The crude product was purified by fast column chromatography with the eluent CH2Cl2-MeOH (98:2, v/v).
References
[1] Russian Journal of Organic Chemistry, 2017, vol. 53, # 5, p. 769 - 776
[2] Zh. Org. Khim., 2017, vol. 53, # 5, p. 756 - 762,7
[3] Journal of Medicinal Chemistry, 1997, vol. 40, # 10, p. 1495 - 1510
H-Glu(OMe)-OtBu Preparation Products And Raw materials
Raw materials
Preparation Products
H-Glu(OMe)-OtBu Suppliers
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
- Tel
- 022-66211079 13212288319
- Fax
- qq1405432731
- sales@chempharmatech.com
- Country
- China
- ProdList
- 923
- Advantage
- 55
- Tel
- 400-711-5280 86-571-81025280
- Fax
- 86-571-85806285
- sales@molcore.com
- Country
- China
- ProdList
- 9967
- Advantage
- 58
- Tel
- 025-58859352 18068836627
- Fax
- 02557626880
- sales01@aikonchem.com
- Country
- China
- ProdList
- 16027
- Advantage
- 58
- Tel
- 0531-61320525 15866703830
- figo.gao@foxmail.com
- Country
- China
- ProdList
- 6163
- Advantage
- 58
- Tel
- +86-0571-81612335 +8613336028439
- sales@nextpeptide.com
- Country
- China
- ProdList
- 19908
- Advantage
- 58
- Tel
- +86-29-89586680 +86-15129568250
- 1026@dideu.com
- Country
- China
- ProdList
- 19282
- Advantage
- 58
- Tel
- +8617735180244
- mike_yan@xuanranglobal.com
- Country
- CHINA
- ProdList
- 4017
- Advantage
- 58
- Tel
- 021-61263389 13524856427
- Fax
- WeChat630417570
- Joetang@glschina.com
- Country
- China
- ProdList
- 9942
- Advantage
- 58
- Tel
- 86-13657291602
- Fax
- 027-59338440
- linda@hubeijusheng.com
- Country
- CHINA
- ProdList
- 22963
- Advantage
- 58