ChemicalBook > CAS DataBase List > 1,3-DibroMo-5-isopropoxybenzene

1,3-DibroMo-5-isopropoxybenzene

Product Name
1,3-DibroMo-5-isopropoxybenzene
CAS No.
1112210-82-8
Chemical Name
1,3-DibroMo-5-isopropoxybenzene
Synonyms
3,5-Dibromoisopropoxybenzene;1,3-DibroMo-5-isopropoxybenzene;1,3-dibromo-5-propan-2-yloxybenzene;Benzene, 1,3-dibromo-5-(1-methylethoxy)-
CBNumber
CB42651963
Molecular Formula
C9H10Br2O
Formula Weight
293.98
MOL File
1112210-82-8.mol
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1,3-DibroMo-5-isopropoxybenzene Property

Boiling point:
276.9±20.0 °C(Predicted)
Density 
1.640±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
Appearance
Colorless to light yellow Liquid
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Safety

HS Code 
2909303890
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D425123
Product name
1,3-Dibromo-5-isopropoxybenzene
Packaging
500mg
Price
$110
Updated
2021/12/16
Apolloscientific
Product number
OR471673
Product name
1,3-Dibromo-5-isopropoxybenzene
Purity
97%
Packaging
5g
Price
$411
Updated
2021/12/16
AK Scientific
Product number
Y3660
Product name
3,5-Dibromoisopropoxybenzene
Packaging
250mg
Price
$80
Updated
2021/12/16
Ambeed
Product number
A177265
Product name
1,3-Dibromo-5-isopropoxybenzene
Purity
97%
Packaging
5g
Price
$107
Updated
2021/12/16
Ambeed
Product number
A177265
Product name
1,3-Dibromo-5-isopropoxybenzene
Purity
97%
Packaging
1g
Price
$15
Updated
2021/12/16
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1,3-DibroMo-5-isopropoxybenzene Chemical Properties,Usage,Production

Synthesis

1435-51-4

67-63-0

1112210-82-8

Synthesis of Intermediate Ia: 60% NaH mineral oil dispersion (1.89 g, 47.25 mmol) was slowly added dropwise to anhydrous DMF (20 mL) at 0 °C and protected by inert atmosphere. Isopropanol (3.62 mL, 47.25 mmol) was then added and the mixture was stirred at 0 °C for 15 min. Next, a solution of 1,3-dibromo-5-fluorobenzene (1.98 mL, 15.75 mmol) in anhydrous DMF (20 mL) was added dropwise at the same temperature. The reaction mixture was brought to room temperature and stirred continuously for 16 hours. Upon completion of the reaction, the reaction was quenched by slow addition of saturated NaHCO3 solution and the crude product was extracted twice with ether (Et2O). The organic layers were combined, washed sequentially with saturated NaHCO3 solution three times and saturated NaCl solution once, dried over anhydrous MgSO4 and concentrated to give yellow oil Ia in quantitative yield.1H NMR (300 MHz, CDCl3) δ 7.11 (t, J = 1.4 Hz, 1H), 6.97 (d, J = 1.5 Hz, 2H), 4.61- 4.40 (m, 1H), 1.32 (d, J = 6.0 Hz, 6H).

References

[1] Patent: WO2013/14170, 2013, A1. Location in patent: Page/Page column 62; 63

1,3-DibroMo-5-isopropoxybenzene Preparation Products And Raw materials

Raw materials

Preparation Products

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1,3-DibroMo-5-isopropoxybenzene Suppliers

Adamas Reagent, Ltd.
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1112210-82-8, 1,3-DibroMo-5-isopropoxybenzeneRelated Search:


  • 1,3-DibroMo-5-isopropoxybenzene
  • 3,5-Dibromoisopropoxybenzene
  • 1,3-dibromo-5-propan-2-yloxybenzene
  • Benzene, 1,3-dibromo-5-(1-methylethoxy)-
  • 1112210-82-8