N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide

Product Name: N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide
CAS No.: 283167-06-6
Chemical Name: N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide
Synonyms: FK962;FK962 ，S0535;FK962, 10 mM in DMSO;N-(1-acetylpiperidin-4-yl)-4-fluorobenzamide;N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide;Benzamide, N-(1-acetyl-4-piperidinyl)-4-fluoro-;Alzheimer,somatostatin,FK-962,FK 962,inhibit,FK962,Inhibitor,cognitive
CBNumber: CB42657132
Molecular Formula: C14H17FN2O2
Formula Weight: 264.3
MOL File: 283167-06-6.mol

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N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide Property

storage temp.: Sealed in dry,Room Temperature
solubility: Soluble in DMSO
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Ambeed

Product number: A979999
Product name: N-(1-Acetylpiperidin-4-yl)-4-fluorobenzamide
Purity: 97%
Packaging: 5mg
Price: $36
Updated: 2021/12/16

Ambeed

Product number: A979999
Product name: N-(1-Acetylpiperidin-4-yl)-4-fluorobenzamide
Purity: 97%
Packaging: 10mg
Price: $50
Updated: 2021/12/16

Ambeed

Product number: A979999
Product name: N-(1-Acetylpiperidin-4-yl)-4-fluorobenzamide
Purity: 97%
Packaging: 25mg
Price: $65
Updated: 2021/12/16

Ambeed

Product number: A979999
Product name: N-(1-Acetylpiperidin-4-yl)-4-fluorobenzamide
Purity: 97%
Packaging: 50mg
Price: $85
Updated: 2021/12/16

Ambeed

Product number: A979999
Product name: N-(1-Acetylpiperidin-4-yl)-4-fluorobenzamide
Purity: 97%
Packaging: 100mg
Price: $147
Updated: 2021/12/16

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N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide Chemical Properties,Usage,Production

Uses

FK962 is an enhancer of somatostatin release, exerts cognitive-enhancing actions. Anti-dementia properties[1].

in vivo

FK962 (0.1, 0.3 or 1.0 mg/kg; i.p.) and Donepezil (a single dose of 1 mg/kg) act synergistically to improve cognition in rats: as an add-on therapy for Alzheimer's disease^[2].

Animal Model:	Male Lister Hooded rats, weighing approximately 270-300^[2]
Dosage:	0.1, 0.3 or 1.0 mg/kg; Donepezil was given as a single dose of 1 mg/kg
Administration:	Administered i.p.
Result:	Resulted in minimal cognition enhancement when given separately. Combination showed a significantly greater effect on cognition.

References

[1] Tokita K, et al. FK962, a novel enhancer of somatostatin release, exerts cognitive-enhancing actions in rats. Eur J Pharmacol. 2005 Dec 19;527(1-3):111-20. DOI:10.1016/j.ejphar.2005.10.022
[2] McCarthy AD, et al. FK962 and donepezil act synergistically to improve cognition in rats: potential as an add-on therapy for Alzheimer's disease. Pharmacol Biochem Behav. 2011 Mar;98(1):76-80. DOI:10.1016/j.pbb.2010.11.019

N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide Suppliers

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283167-06-6, N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMideRelated Search:

CELLULOSE ACETATE Sulfanilamide N-ACETYLLACTOSAMINE

N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide

FK962

N-(1-acetylpiperidin-4-yl)-4-fluorobenzamide

Benzamide, N-(1-acetyl-4-piperidinyl)-4-fluoro-

Alzheimer,somatostatin,FK-962,FK 962,inhibit,FK962,Inhibitor,cognitive

FK962, 10 mM in DMSO

FK962 ，S0535

283167-06-6