1H-Isoindole-1,3(2H)-dione, 5-[5-[[3-(4-broMophenyl)-2-iMino-4-oxo-5-thiazolidinylidene]Methyl]-2-furanyl]-

ChemicalBook > CAS DataBase List > 1H-Isoindole-1,3(2H)-dione, 5-[5-[[3-(4-broMophenyl)-2-iMino-4-oxo-5-thiazolidinylidene]Methyl]-2-furanyl]-

1H-Isoindole-1,3(2H)-dione, 5-[5-[[3-(4-broMophenyl)-2-iMino-4-oxo-5-thiazolidinylidene]Methyl]-2-furanyl]-

Product Name: 1H-Isoindole-1,3(2H)-dione, 5-[5-[[3-(4-broMophenyl)-2-iMino-4-oxo-5-thiazolidinylidene]Methyl]-2-furanyl]-
CAS No.: 1420071-30-2
Chemical Name: 1H-Isoindole-1,3(2H)-dione, 5-[5-[[3-(4-broMophenyl)-2-iMino-4-oxo-5-thiazolidinylidene]Methyl]-2-furanyl]-
Synonyms: CS-1259;BioyMifi;(DR5 ACTIVATOR);Bioymifi (~90%);Bioymifi >=98% (HPLC);Bioymifi, 1420071-30-2;Bioymifi, DR5 Activator;Bioymifi,DR5 Activator, >95%;Bioymifi/High quality/Best price;(Z)-5-(5-[(3-[4-Bromophenyl]-2-imino-4-oxothiazolidin-5-ylidene)methyl]furan-2-yl)isoindoline-1,3-dione
CBNumber: CB42667852
Molecular Formula: C22H12BrN3O4S
Formula Weight: 494.32
MOL File: 1420071-30-2.mol

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1H-Isoindole-1,3(2H)-dione, 5-[5-[[3-(4-broMophenyl)-2-iMino-4-oxo-5-thiazolidinylidene]Methyl]-2-furanyl]- Property

Density: 1.75±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: soluble2mg/mL, clear (warmed)
form: powder
pka: 9.62±0.20(Predicted)
color: orange to dark orange red

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1031
Product name: Bioymifi
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $140
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML1031
Product name: Bioymifi
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $430
Updated: 2024/03/01

Cayman Chemical

Product number: 14242
Product name: Bioymifi
Purity: ≥95%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 14242
Product name: Bioymifi
Purity: ≥95%
Packaging: 5mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 14242
Product name: Bioymifi
Purity: ≥95%
Packaging: 10mg
Price: $199
Updated: 2024/03/01

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1H-Isoindole-1,3(2H)-dione, 5-[5-[[3-(4-broMophenyl)-2-iMino-4-oxo-5-thiazolidinylidene]Methyl]-2-furanyl]- Chemical Properties,Usage,Production

Description

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TNF-related apoptosis-inducing ligand (TRAIL or Apo2L), a member of this family, activates apoptosis in a variety of tumor cell lines by signaling through the death receptors, DR4 and DR5. Bioymifi directly activates DR5 (K_d = 1.2 μM; IC₅₀ = 2 μM), inducing DR5 clustering, which leads to the initiation of FADD/caspase-8-dependent apoptosis in various cancer cells.

Uses

Bioymifi is thiazolidinone derivative that induces apoptosis. It is TRAIL receptor DR5 binding agent useful in human cancer cells.

1H-Isoindole-1,3(2H)-dione, 5-[5-[[3-(4-broMophenyl)-2-iMino-4-oxo-5-thiazolidinylidene]Methyl]-2-furanyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1H-Isoindole-1,3(2H)-dione, 5-[5-[[3-(4-broMophenyl)-2-iMino-4-oxo-5-thiazolidinylidene]Methyl]-2-furanyl]- manufacturers

Career Henan Chemical Co

Product: 1H-Isoindole-1,3(2H)-dione, 5-[5-[[3-(4-broMophenyl)-2-iMino-4-oxo-5-thiazolidinylidene]Methyl]-2-furanyl]- 1420071-30-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 20kg
Release date: 2019-09-05

1420071-30-2, 1H-Isoindole-1,3(2H)-dione, 5-[5-[[3-(4-broMophenyl)-2-iMino-4-oxo-5-thiazolidinylidene]Methyl]-2-furanyl]-Related Search:

(Z)-5-(5-((3-(4-bromophenyl)-2-imino-4-oxothiazolidin-5-ylidene)methyl)furan-2-yl)isoindoline-1,3-dione (Bioymifi)

1H-Isoindole-1,3(2H)-dione, 5-[5-[[3-(4-broMophenyl)-2-iMino-4-oxo-5-thiazolidinylidene]Methyl]-2-furanyl]-

BioyMifi

(E)-5-(5-((3-(4-bromophenyl)-2-imino-4-oxothiazolidin-5-ylidene)methyl)furan-2-yl)isoindoline-1,3-dione

Bioymifi 1H-Isoindole-1,3(2H)-dione, 5-[5-[[3-(4-broMophenyl)-2-iMino-4-oxo-5-thiazolidinylidene]Methyl]-2-furanyl]-

Bioymifi, 1420071-30-2

(Z)-5-(5-[(3-[4-Bromophenyl]-2-imino-4-oxothiazolidin-5-ylidene)methyl]furan-2-yl)isoindoline-1,3-dione

5-[5-[[(5Z)-3-(4-Bromophenyl)-2-imino-4-oxo-5-thiazolidinylidene]methyl]-2-furanyl]-1H-isoindole-1,3(2H)-dione

Bioymifi,DR5 Activator, >95%

Bioymifi, DR5 Activator

CS-1259

(DR5 ACTIVATOR)

Bioymifi (~90%)

1H-Isoindole-1,3(2H)-dione, 5-[5-[[(5Z)-3-(4-bromophenyl)-2-imino-4-oxo-5-thiazolidinylidene]methyl]-2-furanyl]-

Bioymifi >=98% (HPLC)

Bioymifi/High quality/Best price

1420071-30-2

C22H12BrN3O4S

Inhibitors