3-broMopiperidine-2,6-dione
- Product Name
- 3-broMopiperidine-2,6-dione
- CAS No.
- 62595-74-8
- Chemical Name
- 3-broMopiperidine-2,6-dione
- Synonyms
- 3-broMopiperidine-2,6-dione;3-Bromo-2,6-piperidinedione;3-BR0M0PIPERIDINE-2, 6-DIONE;2,6-Piperidinedione, 3-bromo-;3-Bromopiperidine-2,6-dione 95%
- CBNumber
- CB42670755
- Molecular Formula
- C5H6BrNO2
- Formula Weight
- 192.01
- MOL File
- 62595-74-8.mol
3-broMopiperidine-2,6-dione Property
- Melting point:
- 107 °C(Solv: chloroform (67-66-3))
- Boiling point:
- 336.4±35.0 °C(Predicted)
- Density
- 1.748±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 10.08±0.40(Predicted)
- InChI
- InChI=1S/C5H6BrNO2/c6-3-1-2-4(8)7-5(3)9/h3H,1-2H2,(H,7,8,9)
- InChIKey
- RYSICGXZRVMXDP-UHFFFAOYSA-N
- SMILES
- N1C(=O)CCC(Br)C1=O
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
N-Bromosuccinimide Price
- Product number
- B6791
- Product name
- 3-Bromopiperidine-2,6-dione
- Purity
- min. 98.0 %
- Packaging
- 5G
- Price
- $90
- Updated
- 2025/07/31
- Product number
- B6791
- Product name
- 3-Bromopiperidine-2,6-dione
- Purity
- min. 98.0 %
- Packaging
- 25G
- Price
- $270
- Updated
- 2025/07/31
- Product number
- B695435
- Product name
- 3-Bromopiperidin-2,6-dione
- Packaging
- 100mg
- Price
- $360
- Updated
- 2021/12/16
- Product number
- 4H48-9-99
- Product name
- 3-Bromopiperidine-2,6-dione
- Packaging
- 250mg
- Price
- $795
- Updated
- 2021/12/16
- Product number
- 5527BB
- Product name
- 3-Bromopiperidine-2,6-dione
- Packaging
- 25g
- Price
- $1229
- Updated
- 2021/12/16
3-broMopiperidine-2,6-dione Chemical Properties,Usage,Production
Uses
3-Bromopiperidin-2,6-dione was in reaction with sodium saccharin to synthesize glutarimides derivatives to observe their activities against Ehrlich ascites carcinoma in Swiss albino mice.A thalidomide analog (I) was prepd. from 2,??3-??dihydro-??3-??thioxo-??1H-??isoindol-??1-??one and 3-??Bromo-??2,??6-??Piperidinedione.
Synthesis
A solution of piperidine-2,6-dione (2.00 g) and liquid bromine (2.82 g, 0.90 mL, 17.7 mmol) in chloroform (15 mL) was slowly added to a 48-mL pressure-resistant glass reaction vessel fitted with a Teflon screw cap. The reaction mixture was heated to 110 degrees F. and the reaction mixture was kept at this reaction temperature and stirred for 45 minutes, the progress of the reaction was monitored by gas chromatography, and at the end of the reaction the reaction mixture was concentrated directly under vacuum to remove the solvated reactant. The crude glutarimide was dissolved in acetone (5 mL) and then sodium azide (3.44 g, 53.1 mmol) was added to this mixture, the reaction mixture then turned blue-violet and the reaction mixture was stirred at room temperature for 24 hours. At the end of the reaction, the reaction mixture was directly separated and purified by silica gel column chromatography, eluting with n-hexane/ethyl acetate (1/1) to give 3-bromopiperidine-2,6-dione.
3-broMopiperidine-2,6-dione Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-broMopiperidine-2,6-dione manufacturers
- Product
- 3-Bromo-2,6-piperidinedione 62595-74-8
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1000
- Release date
- 2024-06-20
- Product
- 3-broMopiperidine-2,6-dione 62595-74-8
- Price
- US $6.68/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2020-01-08