ChemicalBook > CAS DataBase List > 3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine

3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine

Product Name
3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine
CAS No.
253168-94-4
Chemical Name
3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine
Synonyms
1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine;1-(3-Ethoxy-4-Methoxyphenyl)-2-MethylsulfonylethylaMine;Apr-im B;Apremilast int;RSYY（Avanafil)-36;Apremilast Impurity W;Apremilast Impurity 42;ApreMilast interMediate;Apremilast EP Impurity H;Apremilast Intermediate I
CBNumber
CB42682646
Molecular Formula
C12H19NO4S
Formula Weight
273.35
MOL File
253168-94-4.mol
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3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine Property

Melting point:
120 °C
Boiling point:
469.6±45.0 °C(Predicted)
Density 
1.195±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly, Heated), Methanol (Slightly)
pka
6.84±0.10(Predicted)
form 
Solid
color 
White to Off-White
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Safety

HS Code 
2922.50.4000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
E1381
Product name
1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine
Packaging
1G
Price
$41
Updated
2024/03/01
TCI Chemical
Product number
E1381
Product name
1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine
Packaging
5G
Price
$123
Updated
2024/03/01
TRC
Product number
E891705
Product name
1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonylethylamine(~10%inorganics)
Packaging
5g
Price
$215
Updated
2021/12/16
TRC
Product number
E891705
Product name
1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonylethylamine(~10%inorganics)
Packaging
10g
Price
$365
Updated
2021/12/16
TRC
Product number
E891705
Product name
1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonylethylamine(~10%inorganics)
Packaging
250mg
Price
$55
Updated
2021/12/16
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3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine Chemical Properties,Usage,Production

Uses

1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonylethylamine is used in the enantioselective synthesis of Apremilast (A729700) aminosulfone using catalytic asymetric hydrogenation. Apremilast EP Impurity H

3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine Suppliers

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View Lastest Price from 3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine manufacturers

Shanghai Affida new material science and technology center
Product
1-(3-ETHOXY-4-METHOXYPHENYL)-2-(METHYLSULFONYL)ETHAN-1-AMINE 253168-94-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99
Supply Ability
10 tons
Release date
2024-03-19
Hangzhou ICH Biofarm Co., Ltd
Product
1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl) ethanamine 253168-94-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
≥1kg
Release date
2023-07-18
Career Henan Chemical Co
Product
3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine 253168-94-4
Price
US $100.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2018-07-31

253168-94-4, 3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMineRelated Search:

ApreMilast-d5 1-(3,4-Dimethoxyphenyl)-2-(methylsulfonyl)ethan-1-amine (S)-N-(2-(1-(3,4-dihydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Apremilast Impurity FA Apremilast (R)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide HHUBRUYPYDODRB-UHFFFAOYSA-N (S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide 3-acetamidophthalic acid Apremilast 3-Ethoxy-4-methoxybenzaldehyde oxime Hexamethyldisilazane Valine 1,4-Benzoquinone (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanaMine 1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl) ethanone (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine N-acetyl-L-leucine salt Posaconazole

  • Apremilast Impurity 42
  • 3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine
  • 1-(3-Ethoxy-4-methoxyphenyl)-2- (methylsulofonyl)ethan-1-amine
  • Apremilast int
  • 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine
  • 1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine
  • 1.1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine
  • 2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulfonyl)eth-2-ylamine
  • 1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine Apremilast
  • 3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethaMine
  • 3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine
  • 1-(3-Ethoxy-4-Methoxyphenyl)-2-MethylsulfonylethylaMine
  • 1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanaMine
  • BenzeneMethanaMine, 3-ethoxy-4-Methoxy-a-[(Methylsulfonyl)Methyl]-
  • ApreMilast interMediate
  • Benzenemethanamine, 3-ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]-
  • Apremilast Intermediate I
  • 3-Ethoxy-4-methoxy-alpha-[(methylsulfonyl)methyl]-benzenemethanamine 1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethylamine
  • Apremilast EP Impurity H
  • 3-ethoxy-4-methoxy-a-[(methylsulfonyl)methyl]-Benzenemethanamine
  • 1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonylethylamine (~10% inorganics)
  • Apremilast Impurity W
  • Apremilast EP Impurity H (Apremilast Des Acetamidophthalic acid Impurity)
  • Apr-im B
  • 3- ethoxy -4- methoxy -alpha-[ (methylsulfonyl) methyl]-benzylamine
  • RSYY（Avanafil)-36
  • 3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine
  • 1-(3-ethoxy-4-methoxyphenyl)-2-(methyl sulfonyl) ethanamine (EP-imp-H)
  • 3-ethoxy-4-methoxy-ALPHA - [(methylsulfonyl) methyl] - phenylmethylamine
  • 1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (Apremilast Impurity)
  • Amino Sulfone Impurity of Apremilast
  • 253168-94-4
  • 253168-94-5
  • apremilast intermediates