6-Amino-5-iodonicotinonitrile

Product Name: 6-Amino-5-iodonicotinonitrile
CAS No.: 1187322-51-5
Chemical Name: 6-Amino-5-iodonicotinonitrile
Synonyms: 6-Amino-5-iodonicotinonitrile;6-amino-5-iodo-3-pyridinecarbonitrile;3-Pyridinecarbonitrile, 6-amino-5-iodo-
CBNumber: CB42691758
Molecular Formula: C6H4IN3
Formula Weight: 245.02
MOL File: 1187322-51-5.mol

More

Less

6-Amino-5-iodonicotinonitrile Property

Boiling point:: 343.8±42.0 °C(Predicted)
Density: 2.11±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 1.08±0.49(Predicted)
Appearance: Light yellow to yellow Solid

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: A612705
Product name: 6-Amino-5-iodonicotinonitrile
Packaging: 50mg
Price: $45
Updated: 2021/12/16

TRC

Product number: A612705
Product name: 6-Amino-5-iodonicotinonitrile
Packaging: 100mg
Price: $90
Updated: 2021/12/16

Matrix Scientific

Product number: 085104
Product name: 6-Amino-5-iodonicotinonitrile
Purity: 97%
Packaging: 500mg
Price: $188
Updated: 2021/12/16

Matrix Scientific

Product number: 085104
Product name: 6-Amino-5-iodonicotinonitrile
Purity: 97%
Packaging: 1g
Price: $289
Updated: 2021/12/16

AK Scientific

Product number: 0656AD
Product name: 6-Amino-5-iodonicotinonitrile
Packaging: 5g
Price: $691
Updated: 2021/12/16

More

Less

6-Amino-5-iodonicotinonitrile Chemical Properties,Usage,Production

Synthesis

4214-73-7

1187322-51-5

Synthesis of 6-amino-5-iodonicotinonitrile: 6-amino-3-pyridinecarbonitrile (10.0 g, 0.081 mol), silver trifluoroacetate (25.5 g, 0.115 mol) and 1,2-dichloroethane (160 mL) were added to a flask and heated and refluxed for 5 hours. Iodine (29.5 g, 0.116 mol) was then added and heating and refluxing was continued for 18 hours. Upon completion of the reaction, the mixture was cooled, filtered, and partitioned between water and 1,2-dichloroethane. The organic and aqueous phases were filtered through diatomaceous earth, respectively. The aqueous phase was extracted repeatedly with 1,2-dichloroethane until depleted, the organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was dissolved in ethyl acetate and washed with sodium thiosulfate solution. The solvent was removed under reduced pressure to give 6.6 g of pale yellow crystalline product, which could be used in the next reaction without further purification.HPLC retention time: 2.57 min; LCMS (m/z): 246 [M + H]+.

References

[1] Journal of Medicinal Chemistry, 2013, vol. 56, # 3, p. 1160 - 1170
[2] Patent: US2015/218155, 2015, A1. Location in patent: Paragraph 0300
[3] Patent: WO2009/112139, 2009, A1. Location in patent: Page/Page column 25

6-Amino-5-iodonicotinonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

6-Amino-5-iodonicotinonitrile Suppliers

China 29 India 1 United States 2 Global 32

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9342
Advantage: 55

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 86(512)5235 8471 17715136450
Fax: 86(512)5235 6881
Email: sales@shiyabiopharm.com
Country: China
ProdList: 4169
Advantage: 58

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

Nanjing Chalf-Pharm Technology Co., Ltd.

Tel: 025-57018978 18251899859
Fax: 025-57018008
Email: sales@chalf-pharm.com
Country: China
ProdList: 5674
Advantage: 50

Yancheng KangdiSen Pharmaceutical Co., Ltd.

Tel: 13812573443
Fax: -
Email: tongbenwan22@163.com
Country: China
ProdList: 1980
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

BePharm Ltd

Tel: 400-685-9117
Fax: 021-51816740
Email: market@bepharm.com
Country: China
ProdList: 15081
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Sichuan BaiPeng Biotechnology Co., Ltd.

Tel: 028-65791793 18140026355
Fax: QQ568470422
Email: 568470422@qq.com
Country: China
ProdList: 9997
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15083
Advantage: 58

Yujinpharma(Tianjin) Technology Co.,Ltd.

Tel: 13370351217 kungfu1217@1
Fax: QQ1400885609
Email: kungfu1217@163.com
Country: China
ProdList: 2720
Advantage: 58

Cool Pharm, Ltd

Tel: 021-58581007 18019463053
Fax: 021-50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12878
Advantage: 58

Xinyi Kaiwu Chemical Technology Co., Ltd.

Tel: 0516-0516-88997009 18651776937
Email: 4164357@qq.com
Country: China
ProdList: 3204
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Shanghai UCHEM Inc.

Tel: 18939844854
Fax: QQ3004479448
Email: sales6@myuchem.com
Country: China
ProdList: 4997
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Beijing Stronger Science Co., Ltd.

Tel: 0531-88924771 15614660963
Email: elsa.hang@strongerscience.com
Country: China
ProdList: 10623
Advantage: 58

Shaanxi Yudingzhuo Medical Technology Co., Ltd.

Tel: 18992018580 18165105898
Fax: QQ:1617857088
Email: 13608210612@163.com
Country: China
ProdList: 2984
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 59936
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39665
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Shanghai Lingfei Pharmaceutical Technology Co., Ltd

Tel: 15618928656
Email: 771909552@qq.com
Country: China
ProdList: 1265
Advantage: 58

Tianjin Xinkangyou Biotechnology Co., LTD

Tel: 19922659386
Email: niuli@tjxkys.cn
Country: China
ProdList: 2995
Advantage: 58

Shanghai Chemilab Biotechnology CO.,Ltd

Tel: 18116465878
Email: kmlb@kaimilaibo.com
Country: China
ProdList: 2627
Advantage: 58

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 17715136450
Email: 2439673774@qq.com
Country: China
ProdList: 15647
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Sichuan Biosynce Pharmatech Co., Ltd.

Tel: +8619950309693
Email: diane@biosynce.com
Country: China
ProdList: 4871
Advantage: 58

Lingmei Experimental Instruments (Shanghai) Co., Ltd.

Tel: 15356162092
Country: CHINA
ProdList: 141
Advantage: 58

1187322-51-5, 6-Amino-5-iodonicotinonitrileRelated Search:

6-AMino-5-iodo-nicotinic acid ETHYL 2-AMINO-3-BROMO-5-PYRIDINECARBOXYLATE 6-AMINO-5-BROMONICOTINIC ACID 6-Amino-5-chloronicotinic acid 2-AMino-5-iodo-nicotinic acid Methyl ester

6-amino-5-iodo-3-pyridinecarbonitrile

6-Amino-5-iodonicotinonitrile

3-Pyridinecarbonitrile, 6-amino-5-iodo-

1187322-51-5