GerMicidin A
- Product Name
- GerMicidin A
- CAS No.
- 150973-78-7
- Chemical Name
- GerMicidin A
- Synonyms
- GerMicidin A;2H-Pyran-2-one, 3-ethyl-4-hydroxy-6-(1-methylethyl)-
- CBNumber
- CB42703734
- Molecular Formula
- C10H14O3
- Formula Weight
- 182.22
- MOL File
- 150973-78-7.mol
GerMicidin A Property
- Boiling point:
- 283.6±40.0 °C(Predicted)
- Density
- 1.130±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- solid
- pka
- 5.36±0.50(Predicted)
N-Bromosuccinimide Price
- Product number
- 20591
- Product name
- Germicidin B
- Purity
- ≥95%
- Packaging
- 500 μg
- Price
- $175
- Updated
- 2024/03/01
- Product number
- 19971
- Product name
- Germicidin A
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $220
- Updated
- 2024/03/01
- Product number
- 19971
- Product name
- Germicidin A
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $984
- Updated
- 2024/03/01
- Product number
- 20591
- Product name
- Germicidin B
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $205
- Updated
- 2022/04/27
- Product number
- 20591
- Product name
- Germicidin B
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $946
- Updated
- 2022/04/27
GerMicidin A Chemical Properties,Usage,Production
Description
Germicidin A is a pyranone originally derived from S. viridochromogenes that acts as a reversible, autoregulative inhibitor of spore germination and hyphal elongation in the genus Streptomyces at concentrations as low as 200 pM. During germination, spores of Streptomyces excrete germicidin A along with other germicidin homologs, which inhibit germination of its own arthrospores. At higher concentrations, germicidin A can inhibit the porcine Na+/K+-activated ATPase (ID50 = 100 μM) and prevent the germination of the cress L. sativum.
Uses
Germicidin A is a pyranone isolated from Streptomyces sp. in 1993. Germicidin A is an extremely potent autoregulator of the sporulation of the producing strain, and spores of closely related species. Inhibition is detected at 0.1 ng/ml and is orders of magnitude more potent than a diverse range of antibiotics.
Uses
Germicidin A is an extremely potent autoregulator.
References
[1] petersen f, zhner h, metzger j w, et al. germicidin, an autoregulative germination inhibitor of streptomyces viridochromogenes nrrl b-1551[j]. the journal of antibiotics, 1993, 46(7): 1126-1138.
[2] aoki y, matsumoto d, kawaide h, et al. physiological role of germicidins in spore germination and hyphal elongation in streptomyces coelicolor a3 (2)[j]. the journal of antibiotics, 2011, 64(9): 607-611.
GerMicidin A Preparation Products And Raw materials
Raw materials
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