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para-Hydroxy Atorvastatin CalciuM Salt

Product Name
para-Hydroxy Atorvastatin CalciuM Salt
CAS No.
265989-44-4
Chemical Name
para-Hydroxy Atorvastatin CalciuM Salt
Synonyms
Amlodipine Impurity 88;4-Hydroxy Atorvastatin;Atorvastatin Impurity J;Atorvastatin Impurity 52;Atorvastatin Impurity 154;Para-Hydroxy Atorvastatin Calcium;4-Hydroxy Atorvastatin HeMicalciuM Salt;calcium,(3S,5S)-7-[2-(4-fluorophenyl)-4-[(4-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate;Atorvastatin impurity 35/para-Hydroxy Atorvastatin Calcium Salt/(3R,5R)-7-[2-(4-fluorophenyl)-4-[(4-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate Calcium Salt;4-Hydroxy-Atorvastatin calcium saltQ: What is 4-Hydroxy-Atorvastatin calcium salt Q: What is the CAS Number of 4-Hydroxy-Atorvastatin calcium salt Q: What is the storage condition of 4-Hydroxy-Atorvastatin calcium salt Q: What are the applications of 4-Hydroxy-Atorvastatin calcium salt
CBNumber
CB42707055
Molecular Formula
C66H70CaF2N4O12
Formula Weight
1189.3564064
MOL File
265989-44-4.mol
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para-Hydroxy Atorvastatin CalciuM Salt Property

storage temp. 
Store at -20°C
solubility 
DMF: 25 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 15 mg/ml; Ethanol: 0.5 mg/ml
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22575
Product name
4-hydroxy Atorvastatin (calcium salt)
Purity
≥90%
Packaging
500μg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
22575
Product name
4-hydroxy Atorvastatin (calcium salt)
Purity
≥90%
Packaging
1mg
Price
$152
Updated
2024/03/01
Cayman Chemical
Product number
22575
Product name
4-hydroxy Atorvastatin (calcium salt)
Purity
≥90%
Packaging
5mg
Price
$515
Updated
2024/03/01
Medical Isotopes, Inc.
Product number
4857
Product name
p-Hydroxyatorvastatincalciumsalt
Purity
98%
Packaging
1mg
Price
$590
Updated
2021/12/16
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para-Hydroxy Atorvastatin CalciuM Salt Chemical Properties,Usage,Production

Description

4-hydroxy Atorvastatin is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.1,2,3,4 Atorvastatin is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 to form 4-hydroxy atorvastatin.1

References

1. Hong, J.H., Youm, J.K., Kwon, M.J., et al. K6PC-5, a direct activator of sphingosine kinase 1, promotes epidermal differentiation through intracellular Ca2+ signaling J. Invest. Dermatol. 128,2166-2178(2008).
2. Dart, A., Jerums, G., Nicholson, G., et al. A multicenter, double-blind, one-year study comparing safety and efficacy of atorvastatin versus simvastatin in patients with hypercholesterolemia Am. J. Cardiol. 80(1),39-44(1997).
3. Group, T.D.A.L.I.S. The effect of aggressive versus standard lipid lowering by atorvastatin on diabetic dyslipidemia. The DALI study: A double-blind, randomized, placebo-controlled trial in patients with type 2 diabetes and diabetic dyslipidemia Diabetes Care 24(8),1335-1341(2001).
4. van Dam, M., Zwart, M., de Beer, F., et al. Long term efficacy and safety of atorvastatin in the treatment of severe type III and combined dyslipidaemia Heart 88(3),234-238(2002).

para-Hydroxy Atorvastatin CalciuM Salt Preparation Products And Raw materials

Raw materials

Preparation Products

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para-Hydroxy Atorvastatin CalciuM Salt Suppliers

China 43 India 2 United States 4 Global 49
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View Lastest Price from para-Hydroxy Atorvastatin CalciuM Salt manufacturers

Hangzhou Huarong Pharm Co., Ltd.
Product
Para-Hydroxy Atorvastatin Calcium Salt 265989-44-4
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
99%
Supply Ability
10KG
Release date
2021-09-17

265989-44-4, para-Hydroxy Atorvastatin CalciuM SaltRelated Search:

P-HYDROXY ATORVASTATIN LACTONE Atorvastatin Impurity 31 Difluoro Atorvastatin Acetonide tert-Butyl Ester 2,3-Dehydroxy Atorvastatin Sodium Salt Atorvastatin IMpurity G Ortho-Hydroxy atorvastatin calcium salt 4-Hydroxy Atorvastatin Lactone-d5 para-Hydroxy Atorvastatin-d5 CalciuM Salt Dihydroxy Diketo Atorvastatin IMpurity 5-Oxo Atorvastatin tert-Butyl Ester Atorvastatin Impurity 46 Atorvastatin Impurity 38 Atorvastatin 3-Oxo Atorvastatin tert-Butyl Ester Atorvastatin Impurity 15 2-[1,2-Bis-(4-fluoro-phenyl)-2-oxo-ethyl]-4-methyl-3-oxo-pentanoic acid phenylamide Atorvastatin Dehydro Lactone Atorvastatin Impurity 20

  • Atorvastatin impurity 35/para-Hydroxy Atorvastatin Calcium Salt/(3R,5R)-7-[2-(4-fluorophenyl)-4-[(4-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate Calcium Salt
  • Atorvastatin Impurity 52
  • 4-Hydroxy Atorvastatin HeMicalciuM Salt
  • 4-Hydroxy Atorvastatin
  • Atorvastatin Impurity J
  • Para-Hydroxy Atorvastatin Calcium
  • Atorvastatin Impurity 154
  • calcium,(3S,5S)-7-[2-(4-fluorophenyl)-4-[(4-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate
  • 4-Hydroxy-Atorvastatin calcium saltQ: What is 4-Hydroxy-Atorvastatin calcium salt Q: What is the CAS Number of 4-Hydroxy-Atorvastatin calcium salt Q: What is the storage condition of 4-Hydroxy-Atorvastatin calcium salt Q: What are the applications of 4-Hydroxy-Atorvastatin calcium salt
  • Amlodipine Impurity 88
  • 265989-44-4