HO-3867

Product Name: HO-3867
CAS No.: 1172133-28-6
Chemical Name: HO-3867
Synonyms: HO-3867;CS-2205;HO-3868;CID 46871899;HO-3867 ，S7501;HO-3867 USP/EP/BP;HO-3867 (HO 3867;HO-3867, 10 mM in DMSO;inhibit,Inhibitor,Apoptosis,STAT,HO 3867,HO-3867;(3E,5E)-3,5-Bis(4-fluorobenzylidene)-1-[(1-hydroxy-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl]-4-piperidinone
CBNumber: CB42710695
Molecular Formula: C28H30F2N2O2
Formula Weight: 464.55
MOL File: 1172133-28-6.mol

More

Less

HO-3867 Property

storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: insoluble in EtOH; insoluble in H2O; ≥18.15 mg/mL in DMSO
form: solid
color: Light yellow to yellow

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 21581
Product name: HO-3867
Purity: ≥98%
Packaging: 1mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 21581
Product name: HO-3867
Purity: ≥98%
Packaging: 5mg
Price: $231
Updated: 2024/03/01

Cayman Chemical

Product number: 21581
Product name: HO-3867
Purity: ≥98%
Packaging: 10mg
Price: $437
Updated: 2024/03/01

ChemScene

Product number: CS-5778
Product name: HO-3867
Purity: 99.68%
Packaging: 5mg
Price: $130
Updated: 2021/12/16

ApexBio Technology

Product number: B4970
Product name: HO-3867
Packaging: 5mg
Price: $140
Updated: 2021/12/16

More

Less

HO-3867 Chemical Properties,Usage,Production

Uses

HO-3867 is a selective and potent STAT3 inhibitor and shows good antitumor activity.

IC 50

STAT3

References

[1] Rath KS et al. HO-3867, a safe STAT3 inhibitor, is selectively cytotoxic to ovarian cancer. Cancer Res. 2014 Apr 15;74(8):2316-27. DOI:10.1158/0008-5472.CAN-13-2433
[2] Hu Y, et al. A novel STAT3 inhibitor HO-3867 induces cell apoptosis by reactive oxygen species-dependent endoplasmic reticulum stress in human pancreatic cancer cells. Anticancer Drugs. 2017 Apr;28(4):392-400. DOI:10.1097/CAD.0000000000000470
[3] Tierney BJ et al. HO-3867, a STAT3 inhibitor induces apoptosis by inactivation of STAT3 activity in BRCA1-mutated ovarian cancer cells. Cancer Biol Ther. 2012 Jul;13(9):766-75 DOI:10.4161/cbt.20559

HO-3867 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

HO-3867 Suppliers

China 74 United States 11 Global 85

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4720
Advantage: 55

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4769
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 18101056239
Email: 3193328036@qq.com
Country: China
ProdList: 29760
Advantage: 68

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

1172133-28-6, HO-3867Related Search:

SH-4-54 Fludarabine 1,9-Pyrazoloanthrone Dasatinib PD 98059 Olaparib

HO-3867 (HO 3867

CS-2205

(3E,5E)-3,5-Bis(4-fluorobenzylidene)-1-[(1-hydroxy-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl]-4-piperidinone

HO-3867

1-[(2,5-dihydro-1-hydroxy-2,2,5,5-tetramethyl-1H-pyrrol-3-yl)methyl]-3,5-bis[(4-fluorophenyl)methylene]-(3E,5E)-4-piperidinone

(3E,5E)-1-[(2,5-Dihydro-1-hydroxy-2,2,5,5-tetramethyl-1H-pyrrol-3-yl)methyl]-3,5-bis[(4-fluorophenyl)methylene]-4-piperidinone

4-Piperidinone, 1-[(2,5-dihydro-1-hydroxy-2,2,5,5-tetramethyl-1H-pyrrol-3-yl)methyl]-3,5-bis[(4-fluorophenyl)methylene]-, (3E,5E)-

HO-3867 USP/EP/BP

HO-3868

inhibit,Inhibitor,Apoptosis,STAT,HO 3867,HO-3867

CID 46871899

HO-3867, 10 mM in DMSO

HO-3867 ，S7501

1172133-28-6

C28H30F2N2O2

Inhibitors