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CPI 360

Product Name
CPI 360
CAS No.
1802175-06-9
Chemical Name
CPI 360
Synonyms
CPI360;CPI-360;CPI 360;CPI-360 (R);CPI360;CPI 360;1H-Indole-3-carboxamide, N-[(1,2-dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-
CBNumber
CB42729358
Molecular Formula
C25H31N3O4
Formula Weight
437.53
MOL File
1802175-06-9.mol
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CPI 360 Property

Boiling point:
712.2±60.0 °C(Predicted)
Density 
1.26±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 10 mg/mL; DMSO: 25 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH7.2) (1:7): 0.12 mg/mL
form 
A crystalline solid
pka
11.01±0.10(Predicted)
InChIKey
PFPSFENQCNMITC-MRXNPFEDSA-N
SMILES
N1([C@@H](C2CCOCC2)C)C2=C(C=CC=C2)C(C(NCC2=C(OC)C=C(C)NC2=O)=O)=C1C
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19125
Product name
CPI-360
Purity
≥98%
Packaging
500μg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
19125
Product name
CPI-360
Purity
≥98%
Packaging
1mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
19125
Product name
CPI-360
Purity
≥98%
Packaging
5mg
Price
$231
Updated
2024/03/01
Cayman Chemical
Product number
19125
Product name
CPI-360
Purity
≥98%
Packaging
10mg
Price
$424
Updated
2024/03/01
AK Scientific
Product number
6715DW
Product name
CID73442743
Packaging
10mg
Price
$569
Updated
2021/12/16
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CPI 360 Chemical Properties,Usage,Production

Description

CPI-360 is a selective EZH2 inhibitor with IC50 values of 0.5 and 2.5 nM for wild-type EZH2 and Y641N mutant EZH2, respectively. It decreases cellular levels of H3K27me3 and H3K27me2 (EC50s = 56 and 65 nM, respectively), triggering cell cycle arrest and ultimately resulting in apoptosis in a large panel of non-Hodgkin’s lymphoma (NHL) cell lines. Twice daily, subcutaneous administration of 200 mg/kg of CPI-360 reduced tumor growth of KARPAS-422 xenografts in mice.

CPI 360 Preparation Products And Raw materials

Raw materials

Preparation Products

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CPI 360 Suppliers

China 72 United States 9 Global 81
Zhengzhou convergence chemical co., LTD
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0371-0371-55153829 18003835034
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Hubei Chuchang Chemical Co., Ltd
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18; 15623560702
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Joy.Ren@aliyun.com
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Haoyuan Chemexpress Co., Ltd.
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021-58950125
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(86) 21-58955996
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AdooQ Bioscience CHINA
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025-58849295 18951903616;
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021-52996696，15000506266 15000506266
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Energy Chemical
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View Lastest Price from CPI 360 manufacturers

Hubei Chuchang Biotech Co., Ltd.
Product
CPI-360 1802175-06-9
Price
US $0.00-0.00/mg
Min. Order
1mg
Purity
98
Supply Ability
100G
Release date
2024-04-17
Career Henan Chemical Co
Product
CPI-360 1802175-06-9
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2020-01-01

1802175-06-9, CPI 360Related Search:


  • CPI 360
  • CPI360
  • CPI-360
  • CPI360;CPI 360
  • CPI-360 (R)
  • 1H-Indole-3-carboxamide, N-[(1,2-dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-
  • 1802175-06-9