ChemicalBook > CAS DataBase List > USP7-IN-1
USP7-IN-1
- Product Name
- USP7-IN-1
- CAS No.
- 1381291-36-6
- Chemical Name
- USP7-IN-1
- Synonyms
- USP7i-1;USP7-IN-1;USP7 inhibitor 1;Inhibitor,inhibit,USP-7-IN-1,USP7IN1,USP7 IN 1,DUBs,Deubiquitinase;7-Chloro-3-((4-hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl)methyl)quinazolin-4(3H)-one;4(3H)-Quinazolinone, 7-chloro-3-[[4-hydroxy-1-(1-oxo-3-phenylpropyl)-4-piperidinyl]methyl]-
- CBNumber
- CB42729378
- Molecular Formula
- C23H24ClN3O3
- Formula Weight
- 425.91
- MOL File
- 1381291-36-6.mol
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USP7-IN-1 Property
- Boiling point:
- 666.2±65.0 °C(Predicted)
- Density
- 1.32±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: ≥ 40 mg/mL (93.92 mM)
- form
- Solid
- pka
- 13.52±0.20(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-3515
- Product name
- USP7-IN-1
- Purity
- 98.92%
- Packaging
- 5mg
- Price
- $420
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-3515
- Product name
- USP7-IN-1
- Purity
- 98.92%
- Packaging
- 10mg
- Price
- $600
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-3515
- Product name
- USP7-IN-1
- Purity
- 98.92%
- Packaging
- 50mg
- Price
- $1800
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-3515
- Product name
- USP7-IN-1
- Purity
- 98.92%
- Packaging
- 100mg
- Price
- $2520
- Updated
- 2021/12/16
Crysdot
- Product number
- CD31003679
- Product name
- USP7-IN-1
- Purity
- 98+%
- Packaging
- 5mg
- Price
- $243
- Updated
- 2021/12/16
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USP7-IN-1 Chemical Properties,Usage,Production
Description
USP7-IN-1 is a selective and reversible inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 77 μM, and can be used for the research of cancer. IC50: 77 μM (USP7)[1]
USP7-IN-1 (Example 2) is a selective and reversible inhibitor of USP7, with an IC50 of 77 μM, and shows no inhibition of USP8, USP5, Uch-L1, Uch-L3 or caspase 3. USP7-IN-1 inhibits the proliferation of HCT116 cells, with a GI50 of 67 μM[1].
References
[1]. SELECTIVE AND REVERSIBLE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7. WO 2013030218 A1
USP7-IN-1 Preparation Products And Raw materials
Raw materials
Preparation Products
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USP7-IN-1 Suppliers
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