ChemicalBook > CAS DataBase List > GV-58

GV-58

Product Name
GV-58
CAS No.
1402821-41-3
Chemical Name
GV-58
Synonyms
V-58;GV-58;GV-58 >=97% (HPLC);GV-58, 10 mM in DMSO;Inhibitor,Calcium Channel,GV58,Ca channels,Ca2+ channels,inhibit,GV-58,GV 58;(R)-2-((6-(((5-Methylthiophen-2-yl)methyl)amino)-9-propyl-9H-purin-2-yl)amino)butan-1-ol;(2R)-2-[[6-[[(5-Methylthiophen-2-yl)methyl]amino]-9-propyl-9H-purin-2-yl]amino]butan-1-ol;1-Butanol, 2-[[6-[[(5-methyl-2-thienyl)methyl]amino]-9-propyl-9H-purin-2-yl]amino]-, (2R)-
CBNumber
CB42730550
Molecular Formula
C18H26N6OS
Formula Weight
374.5
MOL File
1402821-41-3.mol
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GV-58 Property

Boiling point:
599.6±60.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 50 mg/mL (133.51 mM);Water : < 0.1 mg/mL (insoluble)
form 
solid
pka
14.56±0.10(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Adipogen Life Sciences
Product number
AG-MR-C0035-M001
Product name
GV-58
Purity
≥97%(NMR)
Packaging
1mg
Price
$50
Updated
2021/12/16
ChemScene
Product number
CS-3617
Product name
GV-58
Purity
99.09%
Packaging
1mg
Price
$96
Updated
2021/12/16
ChemScene
Product number
CS-3617
Product name
GV-58
Purity
99.09%
Packaging
5mg
Price
$360
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0009779
Product name
GV-58
Purity
95.00%
Packaging
5MG
Price
$505.71
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611562
Product name
GV-58
Packaging
100mg
Price
$1654.1
Updated
2021/12/16
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GV-58 Chemical Properties,Usage,Production

Biological Activity

GV-58 is a roscovitine analog th at retains the ability to prolong the open state of calcium channels, but unlike roscovitine, is inactive against Cdk activity. GV-58 is a selective agonist of N-type and P/Q type calcium channels, which are critical to the triggering of neurotransmitter release at the neuromuscular junction. GV-58 has been studied as a possible therapeutic agent in a mouse model of Lambert-Eaton myasthenic syndrome (LEMS). The EC50 values for activation of N-, P/Q- and L- type calcium channels are 6.8, 9.9 and >100 μM, respectively.

storage

+4°C

GV-58 Preparation Products And Raw materials

Raw materials

Preparation Products

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GV-58 Suppliers

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1402821-41-3, GV-58Related Search:

Adenosine N,N-Dimethylformamide

  • GV-58
  • (2R)-2-[[6-[[(5-Methylthiophen-2-yl)methyl]amino]-9-propyl-9H-purin-2-yl]amino]butan-1-ol
  • 1-Butanol, 2-[[6-[[(5-methyl-2-thienyl)methyl]amino]-9-propyl-9H-purin-2-yl]amino]-, (2R)-
  • GV-58 >=97% (HPLC)
  • (R)-2-((6-(((5-Methylthiophen-2-yl)methyl)amino)-9-propyl-9H-purin-2-yl)amino)butan-1-ol
  • Inhibitor,Calcium Channel,GV58,Ca channels,Ca2+ channels,inhibit,GV-58,GV 58
  • V-58
  • GV-58, 10 mM in DMSO
  • 1402821-41-3
  • C18H26N6OS