Tradipitant

Product Name: Tradipitant
CAS No.: 622370-35-8
Chemical Name: Tradipitant
Synonyms: VLY 686;LY686017;Biafungin;Tradipitant;VLY-686;LY686017;Tradipitant(VLY-686);Tradipitant, 10 mM in DMSO;tradipitant,VLY-686, LY686017;(2-(1-(3,5-Bis(trifluoromethyl)benzyl)-5-(pyridin-4-yl)-1H-1,2,3-triazol-4-yl)pyridin-3-yl)(2-;VLY 686,LY-686017,Neurokinin Receptor,VLY686,LY 686017,Inhibitor,Tradipitant,NK receptor,Tachykinin receptor,inhibit
CBNumber: CB42731153
Molecular Formula: C28H16ClF6N5O
Formula Weight: 587.9
MOL File: 622370-35-8.mol

More

Less

Tradipitant Property

Melting point:: 143 - 145°C
Boiling point:: 640.9±65.0 °C(Predicted)
Density: 1.45±0.1 g/cm3(Predicted)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
form: Solid
pka: 2.92±0.10(Predicted)
color: Pale Beige to Brown
InChIKey: CAVRKWRKTNINFF-UHFFFAOYSA-N
SMILES: C(C1=CC=CN=C1C1=C(C2C=CN=CC=2)N(CC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)N=N1)(C1=CC=CC=C1Cl)=O

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

TRC

Product number: T719025
Product name: Tradipitant
Packaging: 10mg
Price: $305
Updated: 2021/12/16

ChemScene

Product number: CS-8056
Product name: Tradipitant
Purity: 99.63%
Packaging: 5mg
Price: $150
Updated: 2021/12/16

ChemScene

Product number: CS-8056
Product name: Tradipitant
Purity: 99.63%
Packaging: 10mg
Price: $250
Updated: 2021/12/16

Crysdot

Product number: CD11087683
Product name: Tradipitant
Purity: 97%
Packaging: 100mg
Price: $602
Updated: 2021/12/16

More

Less

Tradipitant Chemical Properties,Usage,Production

Uses

Tradipitant, is a neurokinin-1 (NK-1) antagonist.

in vivo

Autoradiography experiments reveal that intravenously administered Tradipitant ([³H]-LY686017) localizes in the guinea pig brain and has a distribution similar to that described for the NK-1 receptor using agonist or antagonist radioligands^[1].

Tradipitant Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Tradipitant Suppliers

China 54 United States 3 Global 57

Taizhou Nanfeng Pharmaceutical Research Institute

Tel: nanfengdrug@163.com; 18616377689
Email: nanfengdrug@163.com
Country: China
ProdList: 20009
Advantage: 58

Xingji Pharmaceutical (Shanghai) Co., Ltd

Tel: 15705593425
Email: support@utgene.com
Country: China
ProdList: 316
Advantage: 58

Bayee Biotech (Anqing) Co., Ltd.

Tel: 0556-5032306 18917961636
Email: wtx@bayeebio.com
Country: China
ProdList: 239
Advantage: 61

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3506
Advantage: 58

Shanghai Haozhixiang Biotechnology Co., Ltd

Tel: 526763801 13301653310
Fax: +86-21-51619052
Email: 526763801@qq.com
Country: China
ProdList: 9273
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

UHN Shanghai Research & Development Co., Ltd.

Tel: 021-58958002 18930822973
Fax: 021-58958618
Email: sales@uhnshanghai.com
Country: China
ProdList: 1984
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

622370-35-8, TradipitantRelated Search:

Biafungin

Tradipitant

tradipitant,VLY-686, LY686017

[2-[1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-(4-pyridinyl)-1H-1,2,3-triazol-4-yl]-3-pyridinyl](2-chlorophenyl)methanone

VLY 686

LY686017

VLY-686;LY686017

Tradipitant(VLY-686)

(2-(1-(3,5-Bis(trifluoromethyl)benzyl)-5-(pyridin-4-yl)-1H-1,2,3-triazol-4-yl)pyridin-3-yl)(2-

Methanone, [2-[1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-(4-pyridinyl)-1H-1,2,3-triazol-4-yl]-3-pyridinyl](2-chlorophenyl)-

VLY 686,LY-686017,Neurokinin Receptor,VLY686,LY 686017,Inhibitor,Tradipitant,NK receptor,Tachykinin receptor,inhibit

(2-(1-(3,5-Bis(trifluoromethyl)benzyl)-5-(pyridin-4-yl)-1H-1,2,3-triazol-4-yl)pyridin-3-yl)(2-chlorophenyl)methanone

Tradipitant, 10 mM in DMSO

(2-(1-(3,5-Bis(trifluoromethyl)benzyl)-5-(pyridin-4-yl)-1H-1,2,3-triazol-4-yl)pyridin-3-yl)(2-chlorophenyl)methanone?, Tradipitant

622370-35-8

C28H16ClF6N5O