Z-360
- Product Name
- Z-360
- CAS No.
- 209219-38-5
- Chemical Name
- Z-360
- Synonyms
- CS-2910;Nastorazepide;Nastorazepide (Z-360);Nastorazepide Calcium;Z-360 (Nastorazepide);Nastorazepide, 10 mM in DMSO;Z360; Z-360; Z 360; NASTORAZEPIDE.;Z360,CCK Receptor,Cholecystokinin Receptor,Inhibitor,Z 360,Nastorazepide,inhibit;3-({[(3R)-5-cyclohexyl-1-(3,3-dimethyl-2-oxobutyl)-2-oxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl]carbamoyl}amino)benzoic acid;3-[[[[(3R)-5-Cyclohexyl-1-(3,3-dimethyl-2-oxobutyl)-2,3,4,5-tetrahydro-2-oxo-1H-1,5-benzodiazepin-3-yl]amino]carbonyl]amino]benzoic acid
- CBNumber
- CB42731173
- Molecular Formula
- C29H36N4O5
- Formula Weight
- 520.62
- MOL File
- 209219-38-5.mol
Z-360 Property
- Boiling point:
- 742.8±60.0 °C(Predicted)
- Density
- 1.29±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO:32.0(Max Conc. mg/mL);61.5(Max Conc. mM)
- form
- Solid
- pka
- 4.16±0.10(Predicted)
- color
- White to off-white
- InChIKey
- VIJCCFFEBCOOIE-JOCHJYFZSA-N
- SMILES
- C(O)(=O)C1=CC=CC(NC(N[C@@H]2CN(C3CCCCC3)C3=CC=CC=C3N(CC(=O)C(C)(C)C)C2=O)=O)=C1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-5383
- Product name
- Nastorazepide
- Purity
- 99.89%
- Packaging
- 5mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- CS-5383
- Product name
- Nastorazepide
- Purity
- 99.89%
- Packaging
- 10mg
- Price
- $210
- Updated
- 2021/12/16
- Product number
- CS-5383
- Product name
- Nastorazepide
- Purity
- 99.89%
- Packaging
- 50mg
- Price
- $690
- Updated
- 2021/12/16
- Product number
- CS-5383
- Product name
- Nastorazepide
- Purity
- 99.89%
- Packaging
- 100mg
- Price
- $1150
- Updated
- 2021/12/16
- Product number
- CSN18099
- Product name
- Nastorazepide
- Packaging
- 1mg
- Price
- $66
- Updated
- 2021/12/16
Z-360 Chemical Properties,Usage,Production
Uses
Nastorazepide (Z-360), selective, orally available, 1,5-benzodiazepine derivative, is a gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antitumor activity[1].
IC 50
CCKBR
References
[1] Kato H, et al. CCK-2/gastrin receptor signaling pathway is significant for gemcitabine-induced gene expression of VEGF in pancreatic carcinoma cells. Life Sci. 2011 Oct 24;89(17-18):603-8. DOI:10.1016/j.lfs.2011.07.019
Z-360 Preparation Products And Raw materials
Raw materials
Preparation Products
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