ChemicalBook > CAS DataBase List > Z-360

Z-360

Product Name
Z-360
CAS No.
209219-38-5
Chemical Name
Z-360
Synonyms
CS-2910;Nastorazepide;Nastorazepide (Z-360);Nastorazepide Calcium;Z-360 (Nastorazepide);Nastorazepide, 10 mM in DMSO;Z360; Z-360; Z 360; NASTORAZEPIDE.;Z360,CCK Receptor,Cholecystokinin Receptor,Inhibitor,Z 360,Nastorazepide,inhibit;3-({[(3R)-5-cyclohexyl-1-(3,3-dimethyl-2-oxobutyl)-2-oxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl]carbamoyl}amino)benzoic acid;3-[[[[(3R)-5-Cyclohexyl-1-(3,3-dimethyl-2-oxobutyl)-2,3,4,5-tetrahydro-2-oxo-1H-1,5-benzodiazepin-3-yl]amino]carbonyl]amino]benzoic acid
CBNumber
CB42731173
Molecular Formula
C29H36N4O5
Formula Weight
520.62
MOL File
209219-38-5.mol
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Z-360 Property

Boiling point:
742.8±60.0 °C(Predicted)
Density 
1.29±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:32.0(Max Conc. mg/mL);61.5(Max Conc. mM)
form 
Solid
pka
4.16±0.10(Predicted)
color 
White to off-white
InChIKey
VIJCCFFEBCOOIE-JOCHJYFZSA-N
SMILES
C(O)(=O)C1=CC=CC(NC(N[C@@H]2CN(C3CCCCC3)C3=CC=CC=C3N(CC(=O)C(C)(C)C)C2=O)=O)=C1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene
Product number
CS-5383
Product name
Nastorazepide
Purity
99.89%
Packaging
5mg
Price
$120
Updated
2021/12/16
ChemScene
Product number
CS-5383
Product name
Nastorazepide
Purity
99.89%
Packaging
10mg
Price
$210
Updated
2021/12/16
ChemScene
Product number
CS-5383
Product name
Nastorazepide
Purity
99.89%
Packaging
50mg
Price
$690
Updated
2021/12/16
ChemScene
Product number
CS-5383
Product name
Nastorazepide
Purity
99.89%
Packaging
100mg
Price
$1150
Updated
2021/12/16
CSNpharm
Product number
CSN18099
Product name
Nastorazepide
Packaging
1mg
Price
$66
Updated
2021/12/16
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Z-360 Chemical Properties,Usage,Production

Uses

Nastorazepide (Z-360), selective, orally available, 1,5-benzodiazepine derivative, is a gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antitumor activity[1].

IC 50

CCKBR

References

[1] Kato H, et al. CCK-2/gastrin receptor signaling pathway is significant for gemcitabine-induced gene expression of VEGF in pancreatic carcinoma cells. Life Sci. 2011 Oct 24;89(17-18):603-8. DOI:10.1016/j.lfs.2011.07.019

Z-360 Preparation Products And Raw materials

Raw materials

Preparation Products

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Z-360 Suppliers

Nantong QuanYi Biotechnology Co., Ltd
Tel
0513-66337626 18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
6001
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
Tel
17702719238 18971495150;
Email
sales@sun-shinechem.com
Country
China
ProdList
1150
Advantage
64
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
SINO High Goal Chemical Technology Co., Ltd.
Tel
021-57646680 18306277365
Fax
2469917557
Email
sunkai@chembiobanksh.com
Country
China
ProdList
2039
Advantage
55
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4827
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
86249
Advantage
60
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
9697
Advantage
55
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
7999
Advantage
62

209219-38-5, Z-360Related Search:


  • Nastorazepide
  • Nastorazepide (Z-360)
  • 3-[[[[(3R)-5-Cyclohexyl-1-(3,3-dimethyl-2-oxobutyl)-2,3,4,5-tetrahydro-2-oxo-1H-1,5-benzodiazepin-3-yl]amino]carbonyl]amino]benzoic acid
  • Nastorazepide Calcium
  • CS-2910
  • Z360; Z-360; Z 360; NASTORAZEPIDE.
  • Benzoic acid, 3-[[[[(3R)-5-cyclohexyl-1-(3,3-dimethyl-2-oxobutyl)-2,3,4,5-tetrahydro-2-oxo-1H-1,5-benzodiazepin-3-yl]amino]carbonyl]amino]-
  • Z360,CCK Receptor,Cholecystokinin Receptor,Inhibitor,Z 360,Nastorazepide,inhibit
  • 3-({[(3R)-5-cyclohexyl-1-(3,3-dimethyl-2-oxobutyl)-2-oxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl]carbamoyl}amino)benzoic acid
  • Nastorazepide, 10 mM in DMSO
  • Z-360 (Nastorazepide)
  • 209219-38-5
  • C29H36N4O5