Pyridoclax

Product Name: Pyridoclax
CAS No.: 1651890-44-6
Chemical Name: Pyridoclax
Synonyms: MR 29072;Pyridoclax;MR-29072;MR 29072;Pyridoclax(MR29072);Pyridoclax (Synonyms: MR-29072);5,6'-Di(pyridin-5-yl)-5'-methyl-3-((E)-2-phenylethenyl)-2,3'-bipyridine;3'-Methyl-3''-[(1E)-2-phenylethenyl]-3,2':5',2'':5'',3'''-quaterpyridine;3,2':5',2'':5'',3'''-Quaterpyridine, 3'-methyl-3''-[(1E)-2-phenylethenyl]-
CBNumber: CB42735535
Molecular Formula: C29H22N4
Formula Weight: 426.51
MOL File: 1651890-44-6.mol

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Pyridoclax Property

Boiling point:: 663.6±55.0 °C(Predicted)
Density: 1.192±0.06 g/cm3(Predicted)
pka: 3.65±0.12(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology

Product number: B4901
Product name: Pyridoclax
Packaging: 5mg
Price: $551
Updated: 2021/12/16

ApexBio Technology

Product number: B4901
Product name: Pyridoclax
Packaging: 10mg
Price: $788
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb612001
Product name: Pyridoclax (MR29072)
Purity: >98%
Packaging: 100mg
Price: $793.9
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb612001
Product name: Pyridoclax (MR29072)
Purity: >98%
Packaging: 250mg
Price: $1504.5
Updated: 2021/12/16

ApexBio Technology

Product number: B4901
Product name: Pyridoclax
Packaging: 2mg
Price: $368
Updated: 2021/12/16

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Pyridoclax Chemical Properties,Usage,Production

Uses

Pyridoclax is a potential Mcl-1 inhibitor.

IC 50

Mcl-1

References

[1] Gloaguen C, et al. First evidence that oligopyridines, α-helix foldamers, inhibit Mcl-1 and sensitize ovarian carcinoma cells to Bcl-xL-targeting strategies. J Med Chem. 2015 Feb 26;58(4):1644-68. DOI:10.1021/jm500672y
[2] Groo AC, et al. Comparison of 2 strategies to enhance Pyridoclax solubility: Nanoemulsion delivery system versus salt synthesis. Eur J Pharm Sci. 2017 Jan 15;97:218-226. DOI:10.1016/j.ejps.2016.11.025

Pyridoclax Preparation Products And Raw materials

Raw materials

Preparation Products

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Pyridoclax Suppliers

China 45 United States 4 Global 49

Shanghai Boyle Chemical Co., Ltd.

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Zhongshan Geometric Biological Technology Co., Ltd.

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Medi-tech Bioscientific Co., Ltd.

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Musechem

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Fan De(Beijing) Biotechnology Co., Ltd.

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1651890-44-6, PyridoclaxRelated Search:

Pyridoclax (Synonyms: MR-29072)

MR-29072;MR 29072

Pyridoclax

5,6'-Di(pyridin-5-yl)-5'-methyl-3-((E)-2-phenylethenyl)-2,3'-bipyridine

MR 29072

Pyridoclax(MR29072)

3'-Methyl-3''-[(1E)-2-phenylethenyl]-3,2':5',2'':5'',3'''-quaterpyridine

3,2':5',2'':5'',3'''-Quaterpyridine, 3'-methyl-3''-[(1E)-2-phenylethenyl]-

1651890-44-6