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GM 6001

Product Name
GM 6001
Chemical Name
GM 6001
Synonyms
GM 6001;GALARDIN;ILOMASTAT;N-[(2R)-2-(HYDROXAMIDOCARBONYLMETHYL)-4-METHYLPENTANOYL]-L-TRYPTOPHAN METHYLAMIDE
CBNumber
CB4285515
Molecular Formula
C20H28N4O4
Formula Weight
388.46
MOL File
Mol file
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GM 6001 Property

Melting point:
>193°C (dec.)
storage temp. 
-20°C
solubility 
Soluble in DMSO
form 
Solid
color 
Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Alfa Aesar
Product number
J64386
Product name
GM 6001
Purity
Negative Control
Packaging
5mg
Price
$272
Updated
2021/12/16
Alfa Aesar
Product number
J64386
Product name
GM 6001
Purity
Negative Control
Packaging
1mg
Price
$78.6
Updated
2021/12/16
Tocris
Product number
2983
Product name
GM 6001
Purity
≥95%(HPLC)
Packaging
10
Price
$320
Updated
2021/12/16
AHH
Product number
API-1944
Product name
ILOMASTAT
Purity
ILOMASTAT
Packaging
1g
Price
$1900
Updated
2021/12/16
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GM 6001 Chemical Properties,Usage,Production

Uses

Treatment of corneal ulcers, inflammatory conditions, and cancers (matrix metalloproteinase inhibitor).

Uses

ilomastat helps prevent the formation of matrix metalloproteinases. Matrix metalloproteinases are a category of enzymes that contribute to the degradation of the extracellular matrix and its proteins, including collagen. Ilomastat helps prevent the formation of this family of enzymes, which protects the skin’s extracellular matrix. It also inhibits certain strains of bacteria and serves as a chelating agent.

Uses

GM 6001 is a useful negative control for GM 6001. It is a cell permeable fibroblast collagenase inhibitor and antagonizes matrix metalloproteases (MMP) potentially involved in angiogenesis.

Biological Activity

Cell permeable: yes', 'Primary Target
MMP-1', 'Product does not compete with ATP.', 'Reversible: no', 'Target Ki: 400 pM for MMP-1; 500 pM for MMP-2; 27 nM for MMP-3; 100 pM for MMP-8; and 200 pM for MMP-9

GM 6001 Preparation Products And Raw materials

Raw materials

Preparation Products

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GM 6001 Suppliers

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  • GM 6001
  • GALARDIN
  • ILOMASTAT
  • N-[(2R)-2-(HYDROXAMIDOCARBONYLMETHYL)-4-METHYLPENTANOYL]-L-TRYPTOPHAN METHYLAMIDE