ChemicalBook > CAS DataBase List > FORMYL PEPTIDE RECEPTOR-LIKE 1 AGONIST, WKYMVM
FORMYL PEPTIDE RECEPTOR-LIKE 1 AGONIST, WKYMVM
- Product Name
- FORMYL PEPTIDE RECEPTOR-LIKE 1 AGONIST, WKYMVM
- CAS No.
- 187986-17-0
- Chemical Name
- FORMYL PEPTIDE RECEPTOR-LIKE 1 AGONIST, WKYMVM
- Synonyms
- WKYMVM;FPRL1 AGONIST, WKYMVM;WKYMVMaMide, W-Peptide;Trp-Lys-Tyr-Met-Val-D-Met;M.W. 856.11 C41H61N9O7S2;WKYMVMAMIDE TRIFLUOROACETATE;WKYMVdM trifluoroacetate salt;TRP-LYS-TYR-MET-VAL-D-MET-NH2;H-Trp-Lys-Tyr-Met-Val-D-Met-NH2;FORMYL PEPTIDE RECEPTOR-LIKE 1 AGONIST, WKYMVM
- CBNumber
- CB4297163
- Molecular Formula
- C41H61N9O7S2
- Formula Weight
- 856.11
- MOL File
- 187986-17-0.mol
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FORMYL PEPTIDE RECEPTOR-LIKE 1 AGONIST, WKYMVM Property
- Boiling point:
- 1269.6±65.0 °C(Predicted)
- Density
- 1.268±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- H2O: >2mg/mL
- form
- powder
- pka
- 9.82±0.15(Predicted)
- color
- white to off-white
- Water Solubility
- Soluble to 2 mg/ml in water
- Sequence
- Trp-Lys-Tyr-Met-Val-{d-Met}-NH2
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- W3020
- Product name
- WKYMVdM trifluoroacetate salt
- Purity
- ≥98% (HPLC), powder
- Packaging
- 1 mg
- Price
- $249
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 344216
- Product name
- Formyl Peptide Receptor-Like 1 Agonist, WKYMVm
- Purity
- The Formyl Peptide Receptor-Like 1 Agonist, WKYMVm controls the biological activity of Formyl Peptide Receptor-Like 1. This small molecule/inhibitor is primarily used for Activators/Inducers applicat
- Packaging
- 5 mg
- Price
- $345
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- W3020
- Product name
- WKYMVdM trifluoroacetate salt
- Purity
- ≥98% (HPLC), powder
- Packaging
- 1mg
- Price
- $242
- Updated
- 2024/03/01
Tocris
- Product number
- 1800
- Product name
- WKYMVm
- Packaging
- 1
- Price
- $162
- Updated
- 2021/12/16
TRC
- Product number
- W980020
- Product name
- WKYMVm
- Packaging
- 1mg
- Price
- $50
- Updated
- 2021/12/16
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FORMYL PEPTIDE RECEPTOR-LIKE 1 AGONIST, WKYMVM Chemical Properties,Usage,Production
Uses
WKYMVm is a lipoxin A4 receptor and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2.
in vivo
WKYMVm (4 mg/kg; Intraperitoneal injection; 3 times; 24 h interval) has a protective effect in rat spinal cord injury model[3].
WKYMVm (2.5 mg/kg; Intraperitoneal injection; 4 days) can alleviate hyperoxy-induced lung injury in neonatal mice[4].
WKYMVm (8 mg/kg; Subcutaneous injection; Once every two days; 2-5 weeks) improves obesity in high-fat fed mouse models[5].
| Animal Model: | Adult female Sprague-Dawley rats (200-220 g) with spinal cord injury[3] |
| Dosage: | 4 mg/kg |
| Administration: | Intraperitoneal injection (i.p.); 3 times with 24 hours intervals |
| Result: | Reduce structural disorders and neuronal loss. Reduced the phosphorylation of ERK1/2 and NF-κB p65 but not p38. |
| Animal Model: | Normoxia or hyperoxic treated newborn mouse pups of C57/BL6[4] |
| Dosage: | 2.5 mg/kg |
| Administration: | Intraperitoneal injection (i.p.); daily from postnatal day (P) 5 to P8. |
| Result: | Significantly attenuated hyperoxia-induced lung inflammation, as evidenced by increased inflammatory cytokines, neutrophils, and alveolar macrophages, and resultant lung injuries, which included impaired alveolarization and angiogenesis, an increased number of apoptotic cells, and reduced levels of growth factors in vivo, such as vascular endothelial growth factor and hepatocyte growth factor. |
| Animal Model: | High fat diet treated male wild-type C57BL/6N mice aged 8 weeks old (21?±?2?g)[5] |
| Dosage: | 8?mg/kg |
| Administration: | Subcutaneous injection (i.h.); once every 2?days; 2 or 5 weeks |
| Result: | Significantly attenuated body weight gain, food intake and increased insulin sensitivity. Markedly ameliorated HFD-induced hepatic steatosis and adipose tissue hypertrophy. Improved lipid metabolism in adipose tissue. Improved leptin signalling in the hypothalamus. |
storage
Store at -20°C
FORMYL PEPTIDE RECEPTOR-LIKE 1 AGONIST, WKYMVM Preparation Products And Raw materials
Raw materials
Preparation Products
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FORMYL PEPTIDE RECEPTOR-LIKE 1 AGONIST, WKYMVM Suppliers
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View Lastest Price from FORMYL PEPTIDE RECEPTOR-LIKE 1 AGONIST, WKYMVM manufacturers
Career Henan Chemical Co
- Product
- WKYMVM 187986-17-0
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-02-13
187986-17-0, FORMYL PEPTIDE RECEPTOR-LIKE 1 AGONIST, WKYMVMRelated Search:
FORMYL PEPTIDE RECEPTOR-LIKE 1 AGONIST, WKYMVM,FPRL1 AGONIST, WKYMVM,WKYMVM-NH2
FORMYL PEPTIDE RECEPTOR-LIKE 1 AGONIST, WKYMVM
WKYMVM-NH2
H-VAL-MET-OH