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6-HYDROXY BUSPIRONE

Product Name
6-HYDROXY BUSPIRONE
CAS No.
125481-61-0
Chemical Name
6-HYDROXY BUSPIRONE
Synonyms
BMY 28674;BMS 528215;6-HYDROXY BUSPIRONE;6’-Hydroxy Buspirone;Buspirone Impurity 17;6-Hydroxy Buspirone solution;Buspirone 6-Hydroxy Metabolite;6-Hydroxy-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9- dione;8-Azaspiro[4.5]decane-7,9-dione, 6-hydroxy-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-
CBNumber
CB4298069
Molecular Formula
C21H31N5O3
Formula Weight
401.5
MOL File
125481-61-0.mol
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6-HYDROXY BUSPIRONE Property

Melting point:
96-99°C
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
InChI
1S/C21H31N5O3/c27-17-16-21(6-1-2-7-21)18(28)19(29)26(17)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9,18,28H,1-4,6-7,10-16H2
InChIKey
KOZNAHJIJGCFJJ-UHFFFAOYSA-N
SMILES
O=C1C(O)C2(CCCC2)CC(N1CCCCN(CC3)CCN3C4=NC=CC=N4)=O
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Safety

WGK Germany 
WGK 2
Storage Class
3 - Flammable liquids
Hazard Classifications
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 2
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
H830800
Product name
6’-HydroxyBuspirone
Packaging
500μg
Price
$120
Updated
2021/12/16
TRC
Product number
H830800
Product name
6’-HydroxyBuspirone
Packaging
1mg
Price
$175
Updated
2021/12/16
TRC
Product number
H830800
Product name
6’-HydroxyBuspirone
Packaging
5mg
Price
$790
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
MTB0001868
Product name
6-HYDROXY BUSPIRONE
Purity
95.00%
Packaging
10MG
Price
$1871.1
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
MTB0001868
Product name
6-HYDROXY BUSPIRONE
Purity
95.00%
Packaging
1MG
Price
$739.2
Updated
2021/12/16
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6-HYDROXY BUSPIRONE Chemical Properties,Usage,Production

Chemical Properties

Off-White to Pale Yellow Solid

Uses

It is a major active metabolite of Buspirone (B689850).

Definition

ChEBI: 6-hydroxy buspirone is a N-arylpiperazine.

IC 50

Rat 5-HT1A Receptor: 4 μM (EC50); D2 Receptor: 3.1 μM (IC50); D3 Receptor: 4.9 μM (IC50); D4 Receptor: 0.85 μM (IC50); Rat 5-HT1A Receptor: 1 μM (EC50)

6-HYDROXY BUSPIRONE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-HYDROXY BUSPIRONE Suppliers

Canada 3 China 31 India 4 United States 5 Global 43
J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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021-50135380
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shchemsky@sina.com
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China
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Cato Research Chemicals Inc.
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020-81960175
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+1-541-2553641
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Quality Control Solutions Ltd.
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BOC Sciences
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16314854226
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United States
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Shenzhen SUNGENING Bio-Medical Co., Ltd.
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0755-0755-28967200-8062 13631290199
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0755-28967200
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wxf@sungening.com
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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+86-400-002-6226 +86-13028896684;
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sales@rrkchem.com
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sgtlifesciences pvt ltd
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+8617013299288
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dj@sgtlifesciences.com
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Guangzhou Dreampharm Biotechnology Co., Ltd.
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020-36607679 19925672674
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QQ 3008233717
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3008233746@qq.com
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China
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125481-61-0, 6-HYDROXY BUSPIRONERelated Search:

Buspirone hydrochloride 2-(1-Piperazinyl)pyrimidine 3,3-Tetramethyleneglutarimide 5-Hydroxy Buspirone 8,8'-(1,4-Butanediyl)bis-8-azaspiro[4.5]decane-7,9-dione Buspirone EP Impurity E Buspirone EP Impurity B 8-(4-Chlorobutyl)-8-azaspiro[4.5]decane-7,9-dione Buspirone EP Impurity C 2,2'-(1,4-Piperazinediyl)bis-pyrimidine Buspirone EP Impurity M Buspirone N-Oxide Gepirone Buspirone 3-hydroxypiperidin-2-one 6-HYDROXY BUSPIRONE (R)-5-HYDROXY-PIPERIDIN-2-ONE

  • 6-HYDROXY BUSPIRONE
  • 6-Hydroxy-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9- dione
  • BMY 28674
  • BMS 528215
  • Buspirone 6-Hydroxy Metabolite
  • Buspirone Impurity 17
  • 8-Azaspiro[4.5]decane-7,9-dione, 6-hydroxy-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-
  • 6’-Hydroxy Buspirone
  • 6-Hydroxy Buspirone solution
  • 125481-61-0
  • C21H31N5O3
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals