Cy5-alkyne
- Product Name
- Cy5-alkyne
- CAS No.
- 1223357-57-0
- Chemical Name
- Cy5-alkyne
- Synonyms
- Cy5-alkyne;Clickable Cy5-alkyne;lipo CY5 (Me) YNE.Cl;3,3-Dimethyl-1-(6-oxo-6-(prop-2-yn-1-ylamino)hexyl)-2-(5-(1,3,3-trimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-3H-indol-1-ium chloride
- CBNumber
- CB42985725
- Molecular Formula
- C35H42ClN3O
- Formula Weight
- 556.19
- MOL File
- 1223357-57-0.mol
Cy5-alkyne Property
- storage temp.
- -20°C
- solubility
- Soluble in DMSO, DMF, DCM
- form
- powder
- color
- Brown to black
- Appearance
- Dark blue solid
- ex/em
- 640/664 nm (PBS buffer)
- ε(extinction coefficient)
- 250000 L⋅mol−1⋅cm−1
- Φ(quantum yield)
- 0.2
- InChIKey
- VOWXUNAERRNFLE-UHFFFAOYSA-N
- SMILES
- C([N+]1=C(C(C)(C)C2=CC=CC=C12)C=CC=CC=C1C(C2=CC=CC=C2N1C)(C)C)CCCCC(=O)NCC#C.[Cl-]
N-Bromosuccinimide Price
- Product number
- 777358
- Product name
- Cy5-alkyne
- Purity
- 95% (HPLC)
- Packaging
- 1mg
- Price
- $169
- Updated
- 2025/07/31
- Product number
- 777358
- Product name
- Cy5-alkyne
- Purity
- 95% (HPLC)
- Packaging
- 5mg
- Price
- $470
- Updated
- 2025/07/31
- Product number
- BP-22528
- Product name
- Cy5alkyne
- Purity
- 96%
- Packaging
- 1mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- BP-22528
- Product name
- Cy5alkyne
- Purity
- 96%
- Packaging
- 5mg
- Price
- $200
- Updated
- 2021/12/16
Cy5-alkyne Chemical Properties,Usage,Production
Description
Cy5 alkyne is a cynaine linker containing an alkyne group, which enables Click Chemistry to attach deeply colored and photostable Cyanine5 fluorophore to various azide-bearing molecules. Cyanine5 is a popular fluorophore that has been widely used for various applications including intact organism imaging.
Chemical Properties
Appearance: Dark blue solid
ex/em: 640/664 nm (PBS buffer)
Extinction coefficient (ε): 250000 L??mol??1??cm??1
Quantum yield (Φ): 0.2
Uses
Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye used to label azide proteins and can be used to analyse post-translational modifications of proteins, glycosylation etc. Cyanine5 alkyne can also be used as a mitochondrial OXPHOS inhibitor to inhibit the growth of cancer stem cells (CSC)[1][2]. Cyanine5 alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
References
[1] Amanda R Burnham-Marusich, et al. Size-matched alkyne-conjugated cyanine fluorophores to identify differences in protein glycosylation. Electrophoresis. 2014 Sep;35(18):2621-5. DOI:10.1002/elps.201400241
[2] Camillo Sargiacomo, et al. MitoTracker Deep Red (MTDR) Is a Metabolic Inhibitor for Targeting Mitochondria and Eradicating Cancer Stem Cells (CSCs), With Anti-Tumor and Anti-Metastatic Activity In Vivo. Front Oncol. 2021 Jul 30;11:678343. DOI:10.3389/fonc.2021.678343
Abs/Em Maxima
646/662 nm
Fluoresene quantum yield
0.2
Extinction Coefficient
250000
CF260
0.03
CF280
0.04
Microscopy Laser Line
633 or 635 nm
Flow Cytometry Laser Line
633 or 635 nm
Spectrally Similar Dyes
Alexa Fluor® 647, CF™ 647 Dye, DyLight™649
Cy5-alkyne Preparation Products And Raw materials
Raw materials
Preparation Products
Cy5-alkyne Suppliers
- Tel
- 021-68781987 13818305065
- sales@energybiopharma.com
- Country
- China
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- 652
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- 58
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- 010-62651721 18610486005
- Fax
- 01062651521-808
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- Country
- China
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- 495
- Advantage
- 60
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
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- Country
- China
- ProdList
- 39966
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- 60
- Tel
- 1-516-6625404
- Fax
- 1-516-927-0118
- support@alfa-chemistry.com
- Country
- United States
- ProdList
- 9171
- Advantage
- 60
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
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- Country
- China
- ProdList
- 71826
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- 60
- Tel
- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
- Country
- China
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- 4952
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- 58
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- 0371-55051623 18137891487
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- QQ：2853979817
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- China
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- 9992
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- 010-82387566 18001021521;
- Fax
- 82387566-801
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- Country
- China
- ProdList
- 10083
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- 58
- Tel
- 021-50895067 18616507272
- Fax
- 021-50895067
- tensus@163.com
- Country
- China
- ProdList
- 8073
- Advantage
- 58
- Tel
- 13892832556
- 2440688701@qq.com
- Country
- China
- ProdList
- 1994
- Advantage
- 58
View Lastest Price from Cy5-alkyne manufacturers
- Product
- Cyanine5 alkyne 1223357-57-0
- Price
- US $0.00/mg
- Min. Order
- 1mg
- Purity
- >99.00%
- Supply Ability
- 1mg
- Release date
- 2024-03-21