FERUTININ
- Product Name
- FERUTININ
- CAS No.
- 41743-44-6
- Chemical Name
- FERUTININ
- Synonyms
- TEFESTROL;FERUTININ;Ferutinin >=98% (HPLC);Ferutinin (high purity);Ferutinin, ERalpha agonist;Ferutinol p-hydroxybenzoate;Jaeschkeanadiol p-hydroxybenzoate;Benzoic acid, 4-hydroxy-, (3R,3aS,4S,8aR)-1,2,3,3a,4,5,8,8a-octahydro-3-hydroxy-6,8a-dimethyl-3-(1-methylethyl)-4-azulenyl ester
- CBNumber
- CB4301709
- Molecular Formula
- C22H30O4
- Formula Weight
- 358.47
- MOL File
- 41743-44-6.mol
FERUTININ Property
- Boiling point:
- 489.0±45.0 °C(Predicted)
- Density
- 1.16±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: Soluble
- form
- White to off-white solid
- pka
- 8.12±0.15(Predicted)
- color
- White to off-white
- LogP
- 5.720 (est)
N-Bromosuccinimide Price
- Product number
- SML1609
- Product name
- Ferutinin
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $134
- Updated
- 2024/03/01
- Product number
- 16554
- Product name
- Ferutinin
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $39
- Updated
- 2024/03/01
- Product number
- 16554
- Product name
- Ferutinin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $115
- Updated
- 2024/03/01
- Product number
- 16554
- Product name
- Ferutinin
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $189
- Updated
- 2024/03/01
- Product number
- Z9835
- Product name
- Ferutinin
- Packaging
- 10mg
- Price
- $309
- Updated
- 2021/12/16
FERUTININ Chemical Properties,Usage,Production
Uses
Ferutinin acts as an agonist for estrogen receptor (ER) α. It also increases calcium permeability of lipid bilayer membranes, mitochondria, thymocytes, sarcoplasmic reticulum, and liposomes.
Biological Activity
Ferutinin can suppress tumor development without causing systemic toxicity in various tumor cells and animal cancer models. It possesses estrogenic properties and a protective role against uterine carcinoma. Ferutinin exhibits anti-cancer action in estrogen-dependent breast cancer cells.', 'Ferutinin is a strong agonist for estrogen receptor (ER)α and agonist/antagonist for Erβ with IC50 values of 33.1 nM for ERα and 180.5 nM for Erβ. It has been shown to have both ionophoretic and apoptotic properties. It increases calcium permeability in the lipid bilayer and has been shown to improve bone regeneration in a r at study. It caused significant regression in tumor size in a mouse colon cancer model.
FERUTININ Preparation Products And Raw materials
Raw materials
Preparation Products
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