4,5-DIBROMOVERATROLE
- Product Name
- 4,5-DIBROMOVERATROLE
- CAS No.
- 37895-73-1
- Chemical Name
- 4,5-DIBROMOVERATROLE
- Synonyms
- Einecs 253-705-2;4,5-DIBROMOVERATROL;4,5-DIBROMOVERATROLE;4,5-Dibromoveratrole, 98+%;Piverium bromide impurity 5;4,5-DIBROMOVERATROLEC8H8Br2O2;1,2-DIBROMO-4,5-DIMETHOXYBENZENE;4,5-Dibromo-1,2-dimethoxybenzene;Benzene, 1,2-dibromo-4,5-dimethoxy-
- CBNumber
- CB4303495
- Molecular Formula
- C8H8Br2O2
- Formula Weight
- 295.96
- MOL File
- 37895-73-1.mol
4,5-DIBROMOVERATROLE Property
- Melting point:
- 90-92°C
- Boiling point:
- 286.6±35.0 °C(Predicted)
- Density
- 1.742±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- color
- White to Orange to Green
- Water Solubility
- Insoluble in water.
- BRN
- 1953148
- InChI
- InChI=1S/C8H8Br2O2/c1-11-7-3-5(9)6(10)4-8(7)12-2/h3-4H,1-2H3
- InChIKey
- ZYCLQXMMFJREPJ-UHFFFAOYSA-N
- SMILES
- C1(Br)=CC(OC)=C(OC)C=C1Br
Safety
- Safety Statements
- 22-24/25
- HS Code
- 2909303840
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H373May cause damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P391Collect spillage. Hazardous to the aquatic environment
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- S813826
- Product name
- 1,2-DIBROMO-4,5-DIMETHOXYBENZENE
- Purity
- AldrichCPR
- Packaging
- 50MG
- Price
- $113
- Updated
- 2025/07/31
- Product number
- D5019
- Product name
- 1,2-Dibromo-4,5-dimethoxybenzene
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $50
- Updated
- 2025/07/31
- Product number
- D5019
- Product name
- 1,2-Dibromo-4,5-dimethoxybenzene
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $154
- Updated
- 2025/07/31
- Product number
- D426505
- Product name
- 4,5-Dibromoveratrole
- Packaging
- 1g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 019483
- Product name
- 1,2-Dibromo-4,5-dimethoxybenzene
- Packaging
- 5g
- Price
- $18
- Updated
- 2021/12/16
4,5-DIBROMOVERATROLE Chemical Properties,Usage,Production
Uses
4,5-Dibromoveratrole is used as chemical intermediates.
Synthesis
91-16-7
37895-73-1
General procedure for the synthesis of 1,2-dibromo-4,5-dimethoxybenzene from o-anisidine: 16.16 g (117 mmol) of 1,2-dimethoxybenzene was dissolved in 120 mL of carbon tetrachloride at 0 °C with stirring. 13.2 mL (257.4 mmol, 41.13 g) of bromine (2.2 eq.) dissolved in 25 mL of carbon tetrachloride was slowly added dropwise for a controlled time of 30 min while maintaining the reaction temperature in the range of 0-5 °C (by inserting bubbles into the reaction solution to expel the hydrogen bromide generated and neutralizing with Na2CO3). After dropwise addition, the reaction mixture was continued to be stirred at 0°C for 2 hours. Upon completion of the reaction, the mixture was poured into an ice-water mixture, and the organic phase was separated and washed sequentially with 10% aqueous NaHSO3 and 10% aqueous NaOH. The organic phase was concentrated by evaporation and dried to give 33.42 g of white solid product as 1,2-dibromo-4,5-dimethoxybenzene in 97% yield. The melting point of the product was unspecified.1H NMR (CDCl3): δ=7.06 (s, 2H); 3.86 (s, 6H).13C NMR (CDCl3): δ=148.8; 115.9; 114.7; 56.2.
References
[1] Tetrahedron Letters, 2004, vol. 45, # 37, p. 6851 - 6853
[2] CrystEngComm, 2011, vol. 13, # 20, p. 6050 - 6056
[3] Chemistry - An Asian Journal, 2012, vol. 7, # 10, p. 2240 - 2252
[4] Patent: US8859763, 2014, B1. Location in patent: Page/Page column 5
[5] Chemistry - A European Journal, 2016, vol. 22, # 24, p. 8113 - 8123
4,5-DIBROMOVERATROLE Preparation Products And Raw materials
Raw materials
Preparation Products
4,5-DIBROMOVERATROLE Suppliers
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View Lastest Price from 4,5-DIBROMOVERATROLE manufacturers
- Product
- 4,5-DIBROMOVERATROLE 37895-73-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-11