ChemicalBook > CAS DataBase List > CYM 50260
CYM 50260
- Product Name
- CYM 50260
- CAS No.
- 1355026-60-6
- Chemical Name
- CYM 50260
- Synonyms
- CYM 50260;CYM50260, 10 mM in DMSO;2-Chloro-3-[2-(2,4-dichlorophenoxy)ethoxy]-6-(fluoromethyl)pyridine;Pyridine, 2-chloro-3-[2-(2,4-dichlorophenoxy)ethoxy]-6-(fluoromethyl)-;Inhibitor,CYM 50260,Lysophospholipid Receptor,analysis,inhibit,LPL Receptor,S1P4-R,CYM50260,aggregation,SAR,platelet,CYM-50260,HSP27,PDGF-AB,synthetic
- CBNumber
- CB43037218
- Molecular Formula
- C14H11Cl3FNO2
- Formula Weight
- 350.6
- MOL File
- 1355026-60-6.mol
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CYM 50260 Property
- Boiling point:
- 469.4±45.0 °C(Predicted)
- Density
- 1.407±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- <35.06mg/ml in DMSO
- pka
- -3.50±0.10(Predicted)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
Tocris
- Product number
- 4677
- Product name
- CYM50260
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $182
- Updated
- 2021/12/16
Tocris
- Product number
- 4677
- Product name
- CYM50260
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $777
- Updated
- 2021/12/16
Usbiological
- Product number
- 255069
- Product name
- CYM 50260
- Packaging
- 10mg
- Price
- $423
- Updated
- 2021/12/16
TRC
- Product number
- C991990
- Product name
- CYM50260
- Packaging
- 2.5mg
- Price
- $205
- Updated
- 2021/12/16
TRC
- Product number
- C991990
- Product name
- CYM50260
- Packaging
- 1mg
- Price
- $95
- Updated
- 2021/12/16
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CYM 50260 Chemical Properties,Usage,Production
Uses
CYM50260 is a potent and exquisitely selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonist with an EC50 of 45 nM. CYM50260 displays no activity against S1P1-R, S1P2-R, S1P3-R and S1P5-R[1].
storage
Store at -20°C
References
[1] Guerrero M, et al. Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P?-R) agonists. Bioorg Med Chem Lett. 2012 Jan 1;22(1):537-42. DOI:10.1016/j.bmcl.2011.10.096
[2] Onuma T, et al. Sphingosine 1-phosphate (S1P) suppresses the collagen-induced activation of human platelets via S1P4 receptor. Thromb Res. 2017 Aug;156:91-100. DOI:10.1016/j.thromres.2017.06.001
CYM 50260 Preparation Products And Raw materials
Raw materials
Preparation Products
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