DMCM hydrochloride

Product Name: DMCM hydrochloride
CAS No.: 1215833-62-7
Chemical Name: DMCM hydrochloride
Synonyms: DMCM HCl;DMCM hydrochloride, 10 mM in DMSO
CBNumber: CB43037243
Molecular Formula: C17H19ClN2O4
Formula Weight: 350.8
MOL File: 1215833-62-7.mol

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DMCM hydrochloride Property

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Soluble in DMSO
form: Solid
color: Light green to green

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H290May be corrosive to metals

H314Causes severe skin burns and eye damage

Precautionary statements

P234Keep only in original container.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P363Wash contaminated clothing before reuse.

P390Absorb spillage to prevent material damage.

P405Store locked up.

P406Store in corrosive resistant/… container with a resistant inner liner.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: D494123
Product name: DMCMHydrochloride
Packaging: 2.5mg
Price: $220
Updated: 2021/12/16

TRC

Product number: D494123
Product name: DMCMHydrochloride
Packaging: 5mg
Price: $330
Updated: 2021/12/16

ChemScene

Product number: CS-5704
Product name: DMCM(hydrochloride)
Purity: 98.14%
Packaging: 5mg
Price: $120
Updated: 2021/12/16

ApexBio Technology

Product number: B7268
Product name: DMCMhydrochloride
Packaging: 5mg
Price: $158
Updated: 2021/12/16

ChemScene

Product number: CS-5704
Product name: DMCM(hydrochloride)
Purity: 98.14%
Packaging: 10mg
Price: $180
Updated: 2021/12/16

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DMCM hydrochloride Chemical Properties,Usage,Production

Uses

DMCM hydrochloride is a nonselective full inverse agonist of benzodiazepine. DMCM shows bnding afinity at human recombinant GABAA αxβ3γ2 receptor subtypes with Kis of 10 nM, 13 nM, 7.5 nM, 2.2 nM for α1, α2, α3, and α5 receptors, respectively[1].

in vivo

DMCM has potent convulsant, proconvulsant and anxiogenic properties in vivo. DMCM (20-60 mg/kg; i.p.) produces modest anxiolytic-like effects in γ2I77 mice^[2].

Animal Model:	Male γ2I77 mice^[2]
Dosage:	20 mg/kg and 60 mg/kg
Administration:	Injected i.p.
Result:	Produced modest anxiolytic-like effects.

storage

Desiccate at RT

References

[1] Chambers MS, et al. An orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of GABAA alpha5 receptors with cognition enhancing properties. J Med Chem. 2004 Nov 18;47(24):5829-32. DOI:10.1021/jm040863t
[2] Lepp E, et al. Agonistic effects of the beta-carboline DMCM revealed in GABA(A) receptor gamma 2 subunit F77I point-mutated mice. Neuropharmacology. 2005 Mar;48(4):469-78. DOI:10.1016/j.neuropharm.2004.11.007

DMCM hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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DMCM hydrochloride Suppliers

China 28 United Kingdom 1 United States 7 USA 1 Global 37

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
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EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
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Advantage: 60

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
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Shenzhen Regent Biochemical Technology Co., Ltd.

Tel: 0755-85201366 18938635012
Fax: 0755-85201366
Email: sales@regentsciences.com
Country: China
ProdList: 9468
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32469
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
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HANGZHOU CLAP TECHNOLOGY CO.,LTD

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Fax: 86-571-88216895
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Country: CHINA
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Jinan ponder chemical co. LTD

Tel: 0531-0000
Email: thinklifescience@163.com
Country: China
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
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1215833-62-7, DMCM hydrochlorideRelated Search:

METHYL-6,7-DIMETHOXY-4-ETHYL-BETA-CARBOLINE-3-CARBOXYLATE 2-AMINO-3-(4-CHLOROBENZOYL)-5,6,7,8-TETRAHYDROBENZOTHIOPHENE

DMCM HCl

DMCM hydrochloride, 10 mM in DMSO

1215833-62-7