3-nitro-N-acrylphenylamine

Product Name: 3-nitro-N-acrylphenylamine
CAS No.: 17090-15-2
Chemical Name: 3-nitro-N-acrylphenylamine
Synonyms: Alflutinib Impurity 12;3-nitro-N-acrylphenylamine;N-(3-nitrophenyl)prop-2-enamide;2-Propenamide, N-(3-nitrophenyl)-;3-nitro-N-acrylphenylamine ISO 9001：2015 REACH
CBNumber: CB43037829
Molecular Formula: C9H8N2O3
Formula Weight: 192.17
MOL File: 17090-15-2.mol

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3-nitro-N-acrylphenylamine Property

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
Appearance: Off-white to yellow Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: N900790
Product name: N-(3-Nitrophenyl)Acrylamide
Packaging: 500mg
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: 3639AL
Product name: N-(3-Nitrophenyl)acrylamide
Packaging: 250mg
Price: $84
Updated: 2021/12/16

AK Scientific

Product number: 3639AL
Product name: N-(3-Nitrophenyl)acrylamide
Packaging: 5g
Price: $199
Updated: 2021/12/16

AK Scientific

Product number: 3639AL
Product name: N-(3-Nitrophenyl)acrylamide
Packaging: 10g
Price: $281
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM1026353
Product name: N-(3-NITROPHENYL)PROP-2-ENAMIDE
Purity: 95.00%
Packaging: 5MG
Price: $503.91
Updated: 2021/12/16

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3-nitro-N-acrylphenylamine Chemical Properties,Usage,Production

Synthesis

814-68-6

99-09-2

17090-15-2

1. 3-Nitroaniline (6.90 g, 50 mmol) was weighed in a 250 mL round bottom flask, dichloromethane (100 mL) was added as solvent and stirring was initiated. 2. The reaction system was cooled to -78 °C and diisopropylethylamine (12.92 g, 100 mmol) was subsequently added to the reaction system. 3. Acryloyl chloride (6.80 g, 75 mmol) was slowly added dropwise to the reaction system under stirring conditions. 4. 4. After the dropwise addition, the reaction mixture was gradually warmed up to room temperature and the reaction was continued with stirring for 2 hours. 5. After completion of the reaction, the solvent was removed by concentration under reduced pressure to give the crude product. 6. The crude product was purified using column chromatography with the eluent being petroleum ether/ethyl acetate (4:1, v/v). 7. The target component was collected and the solvent was removed under reduced pressure to afford N-(3-nitrophenyl)acrylamide (9.6 g, 80% yield) as a yellow solid.

References

[1] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 21, p. 5505 - 5512
[2] European Journal of Medicinal Chemistry, 2017, vol. 126, p. 444 - 455
[3] Bioorganic and Medicinal Chemistry, 2018, vol. 26, # 14, p. 4179 - 4186
[4] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 2, p. 765 - 772
[5] European Journal of Medicinal Chemistry, 2018, vol. 143, p. 1847 - 1857

3-nitro-N-acrylphenylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-nitro-N-acrylphenylamine Suppliers

China 31 India 1 United States 3 Global 35

Adamas Reagent, Ltd.

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17090-15-2, 3-nitro-N-acrylphenylamineRelated Search:

3-nitro-N-acrylphenylamine

N-(3-nitrophenyl)prop-2-enamide

2-Propenamide, N-(3-nitrophenyl)-

3-nitro-N-acrylphenylamine ISO 9001：2015 REACH

Alflutinib Impurity 12

17090-15-2