ChemicalBook > CAS DataBase List > (1S,3R,5S)-2-tert-Butyl 3-ethyl 2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate

(1S,3R,5S)-2-tert-Butyl 3-ethyl 2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate

Product Name
(1S,3R,5S)-2-tert-Butyl 3-ethyl 2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate
CAS No.
871727-40-1
Chemical Name
(1S,3R,5S)-2-tert-Butyl 3-ethyl 2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate
Synonyms
Saxagliptin Impurity 48;ethyl (1s,3r,5s)-2-boc-2-azabicyclo[3.1.0]hexane-3-carboxylate;(1S,3R,5S)-2-tert-Butyl 3-ethyl 2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate;2-(tert-butyl) 3-ethyl (1s,3r,5s)-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate;O2-tert-butyl O3-ethyl (1S,3R,5S)-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate;2-Azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid, 2-(1,1-dimethylethyl)3-ethyl ester, (1S,3R,5S)-
CBNumber
CB43052264
Molecular Formula
C13H21NO4
Formula Weight
255.31
MOL File
871727-40-1.mol
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(1S,3R,5S)-2-tert-Butyl 3-ethyl 2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate Property

Boiling point:
321.7±25.0 °C(Predicted)
Density 
1.161±0.06 g/cm3(Predicted)
storage temp. 
Store at room temperature
pka
-2.71±0.40(Predicted)
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

H320Causes eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC
Product number
A795380
Product name
(1S,3R,5S)-2-Azabicyclo[3.1.0]hexane-2,3-dicarboxylicAcid2-(1,1-Dimethylethyl)3-ethylEster
Packaging
5mg
Price
$85
Updated
2021/12/16
Activate Scientific
Product number
AS58046
Product name
Ethyl (1s,3r,5s)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylate
Purity
95+% ee
Packaging
25mg
Price
$170
Updated
2021/12/16
Activate Scientific
Product number
AS58046
Product name
Ethyl (1s,3r,5s)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylate
Purity
95+% ee
Packaging
100mg
Price
$355
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0065783
Product name
(1S,3R,5S)-2-TERT-BUTYL-3-ETHYL 2-AZABICYCLO[3.1.0]HEXANE-2,3-DICARBOXYLATE
Purity
95.00%
Packaging
5MG
Price
$505.37
Updated
2021/12/16
Activate Scientific
Product number
AS58046
Product name
Ethyl (1s,3r,5s)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylate
Purity
95+% ee
Packaging
250mg
Price
$671
Updated
2021/12/16
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(1S,3R,5S)-2-tert-Butyl 3-ethyl 2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate Chemical Properties,Usage,Production

Uses

(1S,3R,5S)-2-Azabicyclo[3.1.0]hexane-2,3-dicarboxylic Acid 2-(1,1-Dimethylethyl) 3-ethyl Ester is a compound used in the preparation of DPP-IV inhibitor saxagliptin.

(1S,3R,5S)-2-tert-Butyl 3-ethyl 2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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(1S,3R,5S)-2-tert-Butyl 3-ethyl 2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate Suppliers

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871727-40-1, (1S,3R,5S)-2-tert-Butyl 3-ethyl 2-azabicyclo[3.1.0]hexane-2,3-dicarboxylateRelated Search:

2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1S,3R,5S)- Saxagliptin Impurity 6 3H-Cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-3-one, 6-aMino-1,1a,4,6a,7,7a-hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-, (1aS,4S,6aR,7aS)- Saxagliptin Impurity 32 1H-Cyclopropa[4,5]pyrrolo[1,2-a]pyrazine-3,6-dione, hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-, (1aS,4S,6aR,7aS)- (1R,3R,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide 2,2,2-trifluoroacetate Saxagliptin Impurity 8 (N-Formyl Saxagliptin) Saxagliptin Impurity 3 ((1S, 3R, 5R, 2'R)-Saxagliptin) Saxagliptin Impurity 34 Saxagliptin Impurity 22 (1R,3S,5R)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXAMIDE 2,2,2-TRIFLUOROACETIC ACID Saxagliptin Impurity 5 (Epoxy saxaglliptin) Saxagliptin Impurity 29 Saxagliptin Impurity 31 Saxagliptin Impurity 24 Saxagliptin Impurity 4 (Deoxy Saxagliptin) Saxagliptin Impurity 33 [15N,2H2]-Saxagliptin Hydrochloride

  • ethyl (1s,3r,5s)-2-boc-2-azabicyclo[3.1.0]hexane-3-carboxylate
  • 2-Azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid, 2-(1,1-dimethylethyl)3-ethyl ester, (1S,3R,5S)-
  • Saxagliptin Impurity 48
  • O2-tert-butyl O3-ethyl (1S,3R,5S)-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate
  • (1S,3R,5S)-2-tert-Butyl 3-ethyl 2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate
  • 2-(tert-butyl) 3-ethyl (1s,3r,5s)-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate
  • 871727-40-1