ChemicalBook > CAS DataBase List > TANNIC ACID

TANNIC ACID

Product Name: TANNIC ACID
CAS No.: 5424-20-4
Chemical Name: TANNIC ACID
Synonyms: TANNIN;TANNINUM;FEMA 3042;GERBSAURE;DIGALLIC ACID;CHINESE TANNIN;Tannic acid, β;CHINESE GALLOTANNIN;TANNIC ACID, 25 G+100 ML H2O;PENTA (M-DIGALLOYL) GLUCOSEN F
CBNumber: CB4305277
Molecular Formula: C76H52O46
Formula Weight: 1701.21
MOL File: 5424-20-4.mol

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TANNIC ACID Property

Melting point:: 218 °C(lit.)
Density: 2.12±0.1 g/cm3(Predicted)
Flash point:: 198 °C
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO:10.0(Max Conc. mg/mL);5.88(Max Conc. mM)
PBS (pH:7.2):0.3(Max Conc. mg/mL);0.176(Max Conc. mM)
form: Solid
pka: 6.00±0.50(Predicted)
color: Off-white to light brown

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Safety

Safety Statements: 24/25
WGK Germany: 2
RTECS: WW5075000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 21421
Product name: Gallotannin
Purity: ≥98%
Packaging: 5g
Price: $19
Updated: 2023/01/06

Cayman Chemical

Product number: 21421
Product name: Gallotannin
Purity: ≥98%
Packaging: 10g
Price: $30
Updated: 2023/01/06

Cayman Chemical

Product number: 21421
Product name: Gallotannin
Purity: ≥98%
Packaging: 25g
Price: $52
Updated: 2023/01/06

Ambeed

Product number: A274873
Product name: Gallotannin
Purity: 96+%
Packaging: 5g
Price: $5
Updated: 2021/12/16

Arctom

Product number: AS062938
Product name: Gallotannin
Purity: ≥96%
Packaging: 5g
Price: $5
Updated: 2021/12/16

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TANNIC ACID Chemical Properties,Usage,Production

Description

Gallotannin is a polyphenol of gallic acid that has been found in various plants and has antioxidant, anti-inflammatory, antiviral, and antiproliferative biological activities. Gallotannin (1 μM) inhibits the intracellular production of reactive oxygen species (ROS) and DNA damage induced by phorbol 12-myristate 13-acetate (TPA; ) in human polymorphonuclear neutrophils (PMNs). It also decreases TPA-induced nitric oxide release by 90% from primary rat hepatocytes when used at a concentration of 0.5 mM. Gallotannin inhibits hepatitis C virus (HCV) entry into Huh7.5 human hepatoma cells (IC₅₀ = 5.8 μM) and inhibits the proliferation of MDA-MB-231 and MCF-7 human breast cancer cells (IC₅₀s = 2.5 and 4 μM, respectively). In a rat model of middle cerebral artery occlusion (MCAO), it increases superoxide dismutase (SOD1) protein levels and decreases the amount of proteins modified by malondialdehyde (MDA) in ischemic brain tissue when administered at a dose of 10 mg/kg.

Uses

Chinese gallotannin is a non-specific promiscuous α-amylase inhibitor with a Ki of 0.82 μg/mL for human salivary α-amylase. Chinese gallotannin can be used for the research of diabetes[1].

Definition

Any of several yellow organic compounds found in vegetable sources such as bark of trees, oak galls, and tea. They are used in tanning animal skins to make leather and as mordants in dyeing. Tannic acid (a type of tannin) is a white solid heterocyclic organic acid extracted from oak galls and used for making dyes and inks.

Definition

tannin: One of a group of complexorganic chemicals (see depsides) commonlyfound in leaves, unripe fruits,and the bark of trees. Their functionis uncertain though the unpleasanttaste may discourage grazing animals.Some tannins have commercialuses, notably in the production ofleather and ink.

References

[1] Szabó K, et al. Gallotannins are non-specific inhibitors of α-amylase: Aggregates are the active species taking part in inhibition. Chem Biol Drug Des. 2021 Feb;97(2):349-357. DOI:10.1111/cbdd.13787

TANNIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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5424-20-4, TANNIC ACIDRelated Search:

Citric acid Hydrogen fluoride Glycerol Oxalic acid dihydrate Malic acid Phytic acid PETROLEUM ETHER Tannic acid

TANNIC ACID, 25 G+100 ML H2O

TANNIN

GERBSAURE

FEMA 3042

CHINESE GALLOTANNIN

CHINESE TANNIN

DIGALLIC ACID

beta-D-glucose pentakis[3,4-dihydroxy-5-[(3,4,5-trihydroxybenzoyl)oxy]benzoate]

β-D-Glucopyranose pentakis[3,4-dihydroxy-5-[(3,4,5-trihydroxybenzoyl)oxy]benzoate]

β-D-Glucopyranose, 1,2,3,4,6-pentakis[3,4-dihydroxy-5-[(3,4,5-trihydroxybenzoyl)oxy]benzoate]

PENTA (M-DIGALLOYL) GLUCOSEN F

TANNINUM

Gallotannin[Pentadigalloylglucose

(2S,3R,4S,5R,6R)-6-(((3,4-Dihydroxy-5-((3,4,5-trihydroxybenzoyl)oxy)benzoyl)oxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetrakis(3,4-dihydroxy-5-((3,4,5-trihydroxybenzoyl)oxy)benzoate)

[2,3-dihydroxy-5-[[(2R,3R,4S,5R,6S)-3,4,5,6-tetrakis[[3,4-dihydroxy-5-(3,4,5-trihydroxybenzoyl)oxybenzoyl]oxy]oxan-2-yl]methoxycarbonyl]phenyl] 3,4,5-trihydroxybenzoate

Tannic acid, β

5424-20-4

C14H10O9

Chiral Building Blocks

Asymmetric Synthesis

Carboxylic Acids

Organic Building Blocks