Q203

Product Name: Q203
CAS No.: 1334719-95-7
Chemical Name: Q203
Synonyms: IAP6;Q203;IAP-6;IAP 6;CS-2499;Telacebec;Q203（IAP6）;Q203 (Q-203;Telacebec (Q203);Q203, 10 mM in DMSO
CBNumber: CB43060627
Molecular Formula: C29H28ClF3N4O2
Formula Weight: 557.01
MOL File: 1334719-95-7.mol

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Q203 Property

Density: 1.34±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 16 mg/ml; DMSO: 14 mg/ml; Ethanol: Slightly soluble
form: A solid
pka: 12.29±0.46(Predicted)
color: White to off-white
InChIKey: OJICYBSWSZGRFB-UHFFFAOYSA-N
SMILES: C12=NC(CC)=C(C(NCC3=CC=C(N4CCC(C5=CC=C(OC(F)(F)F)C=C5)CC4)C=C3)=O)N1C=C(Cl)C=C2

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 37323
Product name: Q203
Purity: ≥98%
Packaging: 1mg
Price: $55
Updated: 2026/04/30

Cayman Chemical

Product number: 37323
Product name: Q203
Purity: ≥98%
Packaging: 5mg
Price: $262
Updated: 2026/04/30

Cayman Chemical

Product number: 37323
Product name: Q203
Purity: ≥98%
Packaging: 10mg
Price: $495
Updated: 2026/04/30

Cayman Chemical

Product number: 37323
Product name: Q203
Purity: ≥98%
Packaging: 25mg
Price: $894
Updated: 2026/04/30

ChemScene

Product number: CS-6412
Product name: Q203
Purity: 99.59%
Packaging: 1mg
Price: $132
Updated: 2021/12/16

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Q203 Chemical Properties,Usage,Production

Uses

Telacebec (Q203) is a midazopyridine amide compound. Telacebec is active against Mycobacterium tuberculosis H37Rv with an MIC50 of 2.7 nM in culture broth medium.

in vivo

Telacebec (Q203) is efficacious in a mouse model of tuberculosis at a dose less than 1 mg per kg body weight. Telacebec displays pharmacokinetic and safety profiles compatible with once-daily dosing. Telacebec has a bioavailability of 90% and a terminal half-life of 23.4 h. The volume of distribution is moderate (5.27 l per kg body weight), and the systemic clearance is low (4.03 mL/min per kg). After 4 weeks of treatment, reductions of 90%, 99% and 99.9% in M. tuberculosis H37Rv bacterial load is observed in the groups treated with Telacebec at 0.4, 2 and 10 mg per kg body weight, respectively^[1].

References

[1] Pethe K, et al. Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis. Nat Med. 2013 Sep;19(9):1157-60. DOI:10.1038/nm.3262

Q203 Preparation Products And Raw materials

Raw materials

Preparation Products

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Q203 Suppliers

China 93 United States 7 Global 100

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9550
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

Tel: 21-57721279 18121011378
Fax: QQ：14057904
Email: sales@shydchem.com.cn
Country: China
ProdList: 998
Advantage: 56

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4827
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 89689
Advantage: 60

Shanghai Changyan Chem & Tech Co., Ltd.

Tel: 18930833303 18930833303
Fax: +86 (21) 2024-2659
Email: sales@changyanchem.cn
Country: China
ProdList: 5001
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 7999
Advantage: 62

Shanghai Rechem science Co., Ltd.

Tel: 021-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2989
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 18101056239
Email: 3193328036@qq.com
Country: China
ProdList: 29661
Advantage: 68

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

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View Lastest Price from Q203 manufacturers

Career Henan Chemical Co

Product: Q203 1334719-95-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98-100%
Supply Ability: 1000kg
Release date: 2018-08-20

1334719-95-7, Q203Related Search:

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1334719-95-7