Lipoamido-PEG8-acid

Product Name: Lipoamido-PEG8-acid
CAS No.: 1334172-70-1
Chemical Name: Lipoamido-PEG8-acid
Synonyms: LA-PEG8-COOH;Lipoamido-PEG8-acid;LIPOAMIDO-PEG8-COOH;Lipoamido-dPEG8-acid;Lipoamido-dPEG(R)8-acid;(R)-Lipoamido-peg8-acid;(R)-Lipoamido-PEG8-CH2CH2COOH;Lipoamido-dPEG??-acid (QBD-10807);Lipoamido-dPEG^?₈-acid;4,7,10,13,16,19,22,25-Octaoxa-28-azatritriacontanoic acid, 33-(3R)-1,2-dithiolan-3-yl-29-oxo-
CBNumber: CB43062520
Molecular Formula: C27H51NO11S2
Formula Weight: 629.82
MOL File: 1334172-70-1.mol

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Lipoamido-PEG8-acid Property

Boiling point:: 748.3±60.0 °C(Predicted)
Density: 1.166±0.06 g/cm3(Predicted)
storage temp.: -20°C
form: solid or viscous liquid
pka: 4.28±0.10(Predicted)
InChIKey: ZIKXLXWMWZSKAA-UHFFFAOYSA-N
SMILES: OC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCC1CCSS1)=O)=O

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Safety

WGK Germany: WGK 3
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: QBD10807
Product name: Lipoamido-dPEG®8-acid
Packaging: 100MG
Price: $386
Updated: 2026/03/19

Sigma-Aldrich

Product number: QBD10807
Product name: Lipoamido-dPEG®8-acid
Packaging: 1000MG
Price: $1860
Updated: 2026/03/19

TRC

Product number: L468713
Product name: Lipoamido-PEG8-acid
Packaging: 1mg
Price: $45
Updated: 2021/12/16

dPEG

Product number: 10807
Product name: Lipoamido-dPEG®₈-acid
Packaging: 100mg
Price: $250
Updated: 2021/12/16

Iris Biotech GmbH

Product number: PEG3510
Product name: Lipoamide-dPEG™(8)-COOH
Packaging: 100mg
Price: $513
Updated: 2021/12/16

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Lipoamido-PEG8-acid Chemical Properties,Usage,Production

Description

Lipoamido-PEG8-acid contains a lipoic acid group and a carboxylic acid moiety. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Lipoic acid contains two sulfur atoms (at C6 and C8) connected by a disulfide bond and is thus considered to be oxidized although either sulfur atom can exist in higher oxidation states. The hydrophilic PEG linker increases the water solubility of the compound.

Uses

Lipoamido-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

reaction suitability

reaction type: Pegylations
reagent type: chemical modification reagent
reagent type: cross-linking reagent
reactivity: gold reactive

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Lipoamido-PEG8-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Lipoamido-PEG8-acid Suppliers

China 38 India 1 United Kingdom 1 United States 4 Global 44

Chengdu Pukang Biotechnology Co., Ltd

Tel: 15680681408 18217049878
Fax: 086-28-82550468
Email: cassie.gao@pu-kang.com
Country: China
ProdList: 468
Advantage: 58

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883
Fax: 0731-82251112
Email: sales@huatengsci.com
Country: China
ProdList: 5873
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
Country: China
ProdList: 1245
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 86249
Advantage: 60

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28772
Advantage: 58

Alpha Biopharmaceuticals Co., Ltd

Tel: 0411-39042497
Fax: 0411-39042693
Email: sales@alphabiopharm.com
Country: China
ProdList: 1951
Advantage: 58

Jiangsu aikang biomedical research and development co., LTD

Tel: 025-58859352 17714375163
Email: qzhang@aikonchem.com
Country: China
ProdList: 15525
Advantage: 58

Henan Alpha Chemical Co., Ltd.

Tel: 0371-55055611 18137792234
Email: 3957071458@qq.com
Country: China
ProdList: 9897
Advantage: 58

1334172-70-1, Lipoamido-PEG8-acidRelated Search:

Lipoamido-PEG8-azide Lipoamide-PEG8-Mal Lipoamido-PEG8-alcohol Lipoamido-dPEG(R)12-acid

Lipoamido-PEG8-acid

LA-PEG8-COOH

LIPOAMIDO-PEG8-COOH

Lipoamido-dPEG(R)8-acid

(R)-Lipoamido-PEG8-CH2CH2COOH

4,7,10,13,16,19,22,25-Octaoxa-28-azatritriacontanoic acid, 33-(3R)-1,2-dithiolan-3-yl-29-oxo-

Lipoamido-dPEG8-acid

(R)-Lipoamido-peg8-acid

(R)-Lipoamido-PEG8-CH2CH2COOH/4,7,10,13,16,19,22,25-Octaoxa-28-azatritriacontanoic acid, 33-(3R)-1,2-dithiolan-3-yl-29-oxo-

Lipoamido-dPEG<sup>?</sup><sub>8</sub>-acid

Lipoamido-dPEG??-acid (QBD-10807)

1334172-70-1

C27H51NO11S2

peg