FEMA 2778 Property

Boiling point:

252 °C(lit.)

Density 

0.89 g/mL at 25 °C(lit.)

FEMA 

2778 | NERYL ISOVALERATE

refractive index 

n20/D 1.458(lit.)

Flash point:

>230 °F

solubility 

Insoluble in water, soluble in alcohol and oils.

color 

Colourless or pale straw-coloured liquid.

Odor

at 100.00 %. sweaty floral rose bergamot citrus fruity

Odor Type

floral

JECFA Number

76

LogP

5.51

EPA Substance Registry System

Neryl isovalerate (3915-83-1)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

2

RTECS 

RG5927710

Toxicity

Both the acute oral LD₅₀ value in rats and the acute dermal LD₅₀ value in rabbits exceeded 5 g/kg (Moreno, 1976).

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

FEMA 2778 Chemical Properties,Usage,Production

Description

Neryl isovalerate has a strong, rich, fruity odor reminiscent of bergamot, clary sage, and petitgrain. It has a bitter taste. Below 10 ppm, the flavor is berry-like, somewhat similar to black currant and apple. May be prepared by esterification of nerol with isovaleric acid.

Chemical Properties

Neryl isovalerate has a strong, rich, fruity odor reminiscent of bergamot, clary sage and petitgrain. It has a bitter flavor. At concentrations below 10 ppm, the flavor is berry-like, somewhat similar to black currant and apple

Occurrence

Has apparently not been reported to occur in nature.

Uses

FEMA 2778 finds a little use in Rose variations, in Oriental bases, and in Oakmoss blends, where it introduces very attractive sweetness and rich-herbaceous notes. As a modifier in heavy florals it may be used sparingly, but it is not often found in a perfume laboratory.

Preparation

By esterification of nerol with isovaleric acid

Aroma threshold values

At 1.0%: sour, sweaty with floral rosy undernotes, and a bergamot citrus nuance and fruity notes of blueberry, cranberry, apple and grape.

Taste threshold values

Taste characteristics at 5 to 20 ppm: fruity, rich floral and slightly citrus-like with berry, waxy nuances of blueberry, fruity notes of apple, grape, peach and apricot