ChemicalBook > CAS DataBase List > 1,2,3,4-TETRAHYDRO-6-QUINOLINECARBOXYLIC ACID

1,2,3,4-TETRAHYDRO-6-QUINOLINECARBOXYLIC ACID

Product Name: 1,2,3,4-TETRAHYDRO-6-QUINOLINECARBOXYLIC ACID
CAS No.: 5382-49-0
Chemical Name: 1,2,3,4-TETRAHYDRO-6-QUINOLINECARBOXYLIC ACID
Synonyms: 1,2,3,4-Tetrahydroquinoline-6-carboxylic acid;6-Carboxy-1,2,3,4-tetrahydroquinoline;Tetrahydroquinoline-6-carboxylic acid;1,2,3,4-Tetrahydro-6-quinolinecarboxylic;1,2,3,4-Tetrahydro-6-quinolinecarboxylicAci;1,2,3,4-TETRAHYDRO-6-QUINOLINECARBOXYLIC ACID;6-Quinolinecarboxylic acid, 1,2,3,4-tetrahydro-;1,2,3,4-Tetrahydroquinoline-6-carboxylic acid 95+%
CBNumber: CB4307206
Molecular Formula: C10H11NO2
Formula Weight: 177.2
MOL File: 5382-49-0.mol

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1,2,3,4-TETRAHYDRO-6-QUINOLINECARBOXYLIC ACID Property

Melting point:: 168 °C
Boiling point:: 382.6±31.0 °C(Predicted)
Density: 1.223±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 4.96±0.20(Predicted)
Appearance: Off-white to yellow Solid

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Safety

Hazard Codes: Xi,T
Risk Statements: 25
Safety Statements: 45
Hazard Note: Irritant
HS Code: 2933499090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: T890288
Product name: 1,2,3,4-Tetrahydro-6-quinolinecarboxylicAcid
Packaging: 100mg
Price: $65
Updated: 2021/12/16

Ark Pharm

Product number: P000556011
Product name: 1,2,3,4-Tetrahydroquinoline-6-carboxylic acid
Purity: 95+%
Packaging: 1g
Price: $118
Updated: 2021/12/16

Ark Pharm

Product number: P000556011
Product name: 1,2,3,4-Tetrahydroquinoline-6-carboxylic acid
Purity: 95+%
Packaging: 100mg
Price: $32
Updated: 2021/12/16

Ark Pharm

Product number: P000556011
Product name: 1,2,3,4-Tetrahydroquinoline-6-carboxylic acid
Purity: 95+%
Packaging: 250mg
Price: $47
Updated: 2021/12/16

Ark Pharm

Product number: P000556011
Product name: 1,2,3,4-Tetrahydroquinoline-6-carboxylic acid
Purity: 95+%
Packaging: 5g
Price: $428
Updated: 2021/12/16

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1,2,3,4-TETRAHYDRO-6-QUINOLINECARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis Reference(s)

The Journal of Organic Chemistry, 39, p. 2044, 1974 DOI: 10.1021/jo00928a014

Synthesis

851202-94-3

5382-49-0

GENERAL STEPS: 1-Acetyl-1,2,3,4-tetrahydroquinoline-6-carbonitrile (50 mmol) was dissolved in 8 M hydrochloric acid (150 mL) and the reaction was carried out at reflux for 18 hours. Upon completion of the reaction, the mixture was cooled and the pH was adjusted with sodium hydroxide solution to about 3. The precipitated 1,2,3,4-tetrahydroquinoline-6-carboxylic acid was separated by filtration, washed with water and dried. Yield: 61%.1H NMR (D6-DMSO) δ: 1.79 (m, 2H), 2.68 (m, 2H), 3.23 (m, 2H), 5.45 (br, 1H), 6.48 (d, 1H), 7.45-7.50 (m, 2H).

References

[1] Patent: WO2005/39572, 2005, A1. Location in patent: Page/Page column 31-32

1,2,3,4-TETRAHYDRO-6-QUINOLINECARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1,2,3,4-TETRAHYDRO-6-QUINOLINECARBOXYLIC ACID manufacturers

Career Henan Chemical Co

Product: 1,2,3,4-TETRAHYDRO-6-QUINOLINECARBOXYLIC ACID 5382-49-0
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg-1000kg
Release date: 2019-12-30

5382-49-0, 1,2,3,4-TETRAHYDRO-6-QUINOLINECARBOXYLIC ACIDRelated Search:

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1,2,3,4-TETRAHYDRO-6-QUINOLINECARBOXYLIC ACID

Tetrahydroquinoline-6-carboxylic acid

6-Carboxy-1,2,3,4-tetrahydroquinoline

1,2,3,4-Tetrahydroquinoline-6-carboxylic acid

1,2,3,4-Tetrahydroquinoline-6-carboxylic acid 95+%

6-Quinolinecarboxylic acid, 1,2,3,4-tetrahydro-

1,2,3,4-Tetrahydro-6-quinolinecarboxylic

1,2,3,4-Tetrahydro-6-quinolinecarboxylicAci

5382-49-0